Results 201 to 210 of about 69,773 (297)

Fruquintinib Plus TAS‐102 With or Without SBRT as Third‐ Or Later‐Line Therapy for Metastatic Colorectal Cancer: Preliminary Results From a Prospective Phase II Trial

open access: yesCancer Medicine, Volume 15, Issue 5, May 2026.
ABSTRACT Both fruquintinib and TAS‐102 monotherapies are guideline‐recommended for third‐line treatment of metastatic colorectal cancer (mCRC). This study aimed to analyze the preliminary outcomes of fruquintinib combined with TAS‐102, with or without stereotactic body radiation therapy (SBRT), as a third‐ or later‐line therapy for mCRC.
Yi Wang   +19 more
wiley   +1 more source

Clinical Characteristics, Gene Mutation Profiles and Prognosis of Patients With Acute Myeloid Leukemia Carrying PHF6 Mutations

open access: yesCancer Medicine, Volume 15, Issue 5, May 2026.
ABSTRACT Background Plant Homeodomain Finger Protein 6 (PHF6) gene mutations are rare in acute myeloid leukemia (AML), with unclear mechanisms and uncertain prognostic value. They may compromise risk stratification and treatment decisions. This study analyzed clinical features and survival outcomes in PHF6‐mutated AML patients, evaluating the impact of
Dongmei Wang   +6 more
wiley   +1 more source

Melanoma: Pathogenesis and Targeted Therapy. [PDF]

open access: yesMedComm (2020)
Fu Y   +5 more
europepmc   +1 more source

Pulmonary Cryptococcal Infection Complicating Gefitinib Therapy in a Patient With EGFR L858R‐Positive Lung Adenocarcinoma: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT In patients with EGFR‐mutant lung adenocarcinoma receiving gefitinib or other EGFR‐TKIs, the development of new pulmonary nodules should not be hastily attributed to disease progression; secondary pulmonary cryptococcosis should be considered in the differential diagnosis.
Yun Wang   +7 more
wiley   +1 more source

AXL is a novel ERK5/KLF4 target in MEK inhibitor-treated melanoma. [PDF]

open access: yesNeoplasia
Paudel R   +5 more
europepmc   +1 more source

Analysis of PLEKHS1 promoter mutation in preoperative thyroid nodule samples

open access: yesCancer Cytopathology, Volume 134, Issue 5, May 2026.
Abstract Indeterminate thyroid nodules carry a wide range of malignancy prevalence, necessitating incorporation of molecular testing to guide management. Molecular test results help guide prognosis to a certain extent, but additional prognostic factors need to be identified.
Sarah Azad   +11 more
wiley   +1 more source

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