Molecular pathology of phyllodes tumours of the breast—much more than MED12
Phyllodes tumours can develop from fibroadenomas bearing MED12 variants by the development of pTERT alterations (“MED12 pathway”) or de novo (“MED12 independent pathway”). Grade progression is associated with increasing genetic complexity including cancer driver gene aberrations. Molecular alterations can be useful in assigning grade and distinguishing
Jia‐Min B Pang +3 more
wiley +1 more source
Effect of RAS Pathway Gene Mutations on Survival in Myelodysplastic Syndrome: A Systematic Review and Meta-Analysis. [PDF]
Eslalakawi Y +9 more
europepmc +1 more source
ABSTRACT Aims To systematically summarise evidence related to the use of non‐sterile gloves when preparing and administering intravenous antimicrobials. Design Scoping review. Methods A rigorous scoping review was undertaken following Arksey and O'Malley's (2005) framework and the modified Preferred Reporting Items for Systematic Reviews and Meta ...
Natasya Raja Azlan +10 more
wiley +1 more source
Exploring the toxicological impact of N-nitrosodimethylamine (NDMA) exposure on bladder urothelial carcinoma (BLCA) through network toxicology, machine learning, and multi-dimensional bioinformatics analysis. [PDF]
Shi Z +6 more
europepmc +1 more source
Survival impact of second primary cutaneous and non‐cutaneous melanoma in melanoma survivors
In this US population‐based cohort study, melanoma survivors diagnosed with regional/distant‐stage SPCM or SPNCM had worse survival compared to those with a single melanoma. Abstract Background Melanoma survivors have a high risk of developing second primary neoplasms, both cutaneous melanoma (SPCM) and non‐cutaneous melanoma (SPNCM), but little is ...
Jingjing Xie +3 more
wiley +1 more source
Ras-Related Mutants Identified in Young-Onset Colorectal Cancer Display Divergent Phenotypes and Retain Their Pro-Angiogenic Effects. [PDF]
David APL +5 more
europepmc +1 more source
Biomarkers in Colorectal Cancer: Clinically Relevant Diagnostic and Prognostic Molecular Features, and the Future of Precision Medicine. [PDF]
Whitmer R +4 more
europepmc +1 more source
Do Women Legislators Legislate Differently Than Men on Gun‐Related Policy? A Suggestive Yes
ABSTRACT Polls show that men are less likely to support gun restrictions than women, but do voter preferences translate into elite behavior? To answer this question, we use a novel dataset of hand‐coded state firearm legislation across six politically diverse states (California, Florida, Iowa, Illinois, Michigan, Texas) to construct an 11‐year panel ...
Patrick Cunha Silva +2 more
wiley +1 more source

