Results 51 to 60 of about 69,773 (297)

Governing information infrastructures and services in telecommunications [PDF]

, 2010
Purpose – Telecommunications comprises a vital component of information infrastructures and services, with a historically strong public interest dimension.
Simpson, S
core   +2 more sources

Extracellular Vesicle‐Transferred ATP‐Citrate Lyase Induces Monocyte Differentiation Toward Tumor‐Associated Macrophages and Fuels Hepatocellular Carcinoma Progression

Advanced Science, EarlyView.
Hepatocellular carcinoma (HCC)‐derived extracellular vesicles (EVs) enrich the metabolic enzyme ATP‐citrate lyase (ACLY). EV‐transferred ACLY enhances palmitate biosynthesis, increases the S‐palmitoylation and stability of multiple immune checkpoint proteins, augments the cellular immunosuppressive activity, and ultimately accelerates the malignant ...
Zhijun Liu, Haihong Lai, Qing Yang, Chaoyue Zhang, Bin Jia, Qiyi Chen, Yuling Deng, Fen Cao, Yuyu You, Zhe Li, Dongming Kuang, Bo Li   +11 more
wiley   +1 more source

miR-6824-3p suppresses hepatitis B virus replication by targeting NRAS to regulate TNF-α secretion in macrophages

Zhongguo shuxue zazhi
[Objective] To investigate the regulatory role of miR-6824-3p in macrophage function and its molecular mechanism in inhibiting hepatitis B virus (HBV) replication, thereby providing experimental evidence to elucidate the immune regulatory mechanisms ...
LIN Simin, CHEN Limin, LI Yujia, LI Shilin   +3 more
doaj   +1 more source

Progress in Strain Engineering of 2D‐Integrated Heterostructures for Ultrasensitive Sensors

Advanced Science, EarlyView.
 . ABSTRACT Two‐dimensional (2D) integrated heterostructures have emerged as a cornerstone in the advancement of next‐generation sensor technologies. These heterostructures, which combine materials with different dimensionalities, have led to significant breakthroughs in sensing performance and device integration.
That Buu Ton, Tuan Sang Tran, Duc Khanh Tran, Van Thanh Dau, Dzung Viet Dao   +4 more
wiley   +1 more source

Impact of NRAS Mutations on the Diagnosis of Follicular Neoplasm of the Thyroid

International Journal of Endocrinology, 2014
Background. Most patients with a preoperative diagnosis of thyroid follicular neoplasm (FN) undergo diagnostic surgery to determine whether the nodule is benign or malignant.
Ja-Seong Bae, Seung Kyu Choi, Sora Jeon, Yourha Kim, Sohee Lee, Youn Soo Lee, Chan Kwon Jung   +6 more
doaj   +1 more source

European Communications at the Crossroads. Report of the CEPS Working Party on electronic communications. CEPS Task Force Reports No. 39, 1 October 2001 [PDF]

, 2001
Community institutions are now busy with the second readings of the proposals for a new regime for regulating the European Communications Industry.
Cave, Martin, Larouche, Pierre.
core  

Differential Prognostic Impact of Prior Cholecystectomy Between Proximal and Distal Colorectal Cancer: A 12‐Year Retrospective Cohort Study of 3487 Consecutive Patients

Annals of Gastroenterological Surgery, EarlyView.
In this retrospective cohort of 3487 patients with CRC, history of CCY was associated with significantly worse prognosis in patients with proximal CRC but not in those with distal CRC. This differential prognostic impact showed a statistically significant interaction between tumor location and history of CCY and remained robust after PSM.
Masashi Tsunematsu, Koichiro Haruki, Kazuhiro Yanamoto, Takuo Takehana, Shunta Ishizaki, Mitsuru Yanagaki, Yoshihiro Shirai, Kenei Furukawa, Shinji Onda, Toru Ikegami   +9 more
wiley   +1 more source

When NRA

, 2020
coverage ...
openaire   +1 more source

Antitumor activity of the ERK inhibitor SCH772984 [corrected] against BRAF mutant, NRAS mutant and wild-type melanoma. [PDF]

, 2014
BackgroundIn melanoma, dysregulation of the MAPK pathway, usually via BRAF(V600) or NRAS(Q61) somatic mutations, leads to constitutive ERK signaling.
Atefi, Mohammad S, Avarappatt, Geetha, Avramis, Earl, Cerniglia, Michael, Comin-Anduix, Begonya, Foulad, David, Graeber, Thomas G, Lassen, Amanda, Lo, Roger S, Ribas, Antoni, Robert, Lidia, Samatar, Ahmed, Tsoi, Jennifer, Wong, Deborah JL   +13 more
core   +1 more source

The first maps of κd - the dust mass absorption coefficient - in nearby galaxies, with DustPedia [PDF]

, 2019
The dust mass absorption coefficient, κd is the conversion function used to infer physical dust masses from observations of dust emission. However, it is notoriously poorly constrained, and it is highly uncertain how it varies, either between or within ...
Baes, Maarten, Bianchi, S, Casasola, V, Cassarà, LP, Clark, CJR, Davies, JI, De Looze, Ilse, De Vis, P, Dobbels, Wouter, Evans, R, Galametz, M, Galliano, F, Jones, AP, Lianou, S, Madden, SC, Mosenkov, AV, Verstocken, Sam, Viaene, Sébastien, Xilouris, EM, Ysard, N   +19 more
core   +1 more source