Results 211 to 220 of about 78,211 (259)

Kaempferol Attenuates Myocardial Ischemia–Reperfusion Injury by Suppressing Ferroptosis via the KEAP1–Nrf2–GPX4 Axis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Myocardial ischemia/reperfusion (I/R) injury is characterized by cardiomyocyte death, excessive oxidative stress, inflammation, and ferroptosis, which collectively limit the efficacy of reperfusion therapy. In this study, we investigated whether kaempferol (KAE), a natural flavonol with antioxidative and antiinflammatory properties, could ...
Yan‐Bo Zhao, Ling‐Ling Sun, Xiao‐Hua Shen, Min Wang, Mei‐Hui Wang, Lu‐Lu Liu, Kai Zhang   +6 more
wiley   +1 more source

Correction: The role of the KEAP1-NRF2 signaling pathway in form deprivation myopia guinea pigs. [PDF]

BMC Ophthalmol
Gu Z, Meng J, Zhong W, Lan C, Tan Q, Xiang X, Zhou H, Liao X.   +7 more
europepmc   +1 more source

Terazosin Attenuates Neuronal Pyroptosis by Regulating the Mitochondrial ROS/NLRP3 Inflammasome Axis Through Mitophagy in Cerebral Ischemia–Reperfusion Injury

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Cerebral ischemia–reperfusion injury (CI/RI) is a major cause of secondary neuronal damage following ischemic stroke. This study investigated whether terazosin (TZ) exerts neuroprotective effects by regulating mitophagy and the reactive oxygen species (ROS)/NOD‐like receptor protein 3 (NLRP3) inflammasome axis.
Wei Wang, Xin‐Yue Han, Li‐An Huang, Yu‐Sheng Zhang, Heng Meng, An‐Ding Xu   +5 more
wiley   +1 more source

Dioscin regulates oxidative stress and autophagy in uric acid-induced HK-2 cells through the P62-KEAP1-NRF2 signaling pathway. [PDF]

BMC Nephrol
Feng J, Zhang W, Liu R, Xiang T, Wu X.
europepmc   +1 more source

<i>Viola tianshanica</i> Maxim Extract Ameliorates Lipopolysaccharide Induced Acute Lung Injury by Regulating NLRP3 Inflammasome and Nrf2 Signaling Pathway. [PDF]

J Microbiol Biotechnol
Liu Y, Shi Y, Xu L, Wang X.
europepmc   +1 more source

Depressed TFAM promotes acetaminophen-induced hepatotoxicity regulated by DDX3X-PGC1α-NRF2 signaling pathway. [PDF]

Mol Med
Chen S, Cao Y, Fan Z, Xu L, Pan Z, Gao Y, Wei L, Wei Q, Tian Y, Zhang X, Liu M, Ren F.   +11 more
europepmc   +1 more source

The role of the KEAP1-NRF2 signaling pathway in form deprivation myopia guinea pigs. [PDF]

BMC Ophthalmol
Gu Z, Meng J, Zhong W, Lan C, Tan Q, Xiang X, Zhou H, Liao X.   +7 more
europepmc   +1 more source

Study on the Regulatory Effect of Water Extract of <i>Artemisia annua</i> L. on Antioxidant Function of Mutton Sheep via the Keap1/Nrf2 Signaling Pathway. [PDF]

Antioxidants (Basel)
Gang G, Gao R, Li R, Jin X, Xing Y, Yan S, Xu Y, Shi B.   +7 more
europepmc   +1 more source

Therapeutic potentials of cannabidiol: Focus on the Nrf2 signaling pathway

Biomedicine and Pharmacotherapy, 2023
Cannabidiol (CBD), a cannabinoid that does not create psychoactive activities, has been identified as having a multitude of therapeutic benefits. This study delves into the chemical properties, pharmacokinetics, safety and toxicity, pharmacological effects, and most importantly, the association between the therapeutic potential of CBD and the nuclear ...
Marjan Talebi, Seyed Abdulmajid Ayatollahi, Elaheh Ainy   +2 more
exaly   +3 more sources