Results 91 to 100 of about 13,650 (179)

Neuropilin1-dependent paracrine signaling of cancer cells mediated by miRNA exosomal cargo

Cell Communication and Signaling
Background Neuropilin-1 (NRP1) is a transmembrane protein involved in surface receptor complexes for a variety of extracellular signals. NRP1 expression in human cancers is associated with prominent angiogenesis and advanced progression stage.
Claudia Palazzo, Roberta Mastrantonio, Noemi Gioelli, Erika Testa, Francesco Recco, Donatella Lucchetti, Giulia Villari, Alessio D’Alessio, Alessandro Sgambato, Flavio Mignone, Guido Serini, Maria Teresa Viscomi, Luca Tamagnone   +12 more
doaj   +1 more source

Neuropilin 1 is essential for gastrointestinal smooth muscle contractility and motility in aged mice.

PLoS ONE, 2015
Background and aimsNeuropilin 1 (NRP1) is a non-tyrosine kinase receptor for vascular endothelial growth factor (VEGF) and class 3 semaphorins, playing a role in angiogenesis and neuronal axon guidance, respectively.
Maiko Yamaji, Marwa Mahmoud, Ian M Evans, Ian C Zachary   +3 more
doaj   +1 more source

Neuropilin-1: A Conserved Entry Receptor for SARS-CoV-2 and a Potential Therapeutic Target

Biomedicines
Background/Objectives: Neuropilin-1 (NRP1) is a key co-receptor for SARS-CoV-2, complementing the ACE2 receptor. Several investigations have documented highly conserved sequences in this receptor, supporting the implication of NRP1 as a key mediator in ...
Vivany Maydel Sierra-Sánchez, Citlali Margarita Blancas-Napoles, Aina Daniela Sánchez-Maldonado, Indira Medina, Rodrigo Romero-Nava, Fengyang Huang, Enrique Hong, Asdrúbal Aguilera-Méndez, Sergio Adrian Ocampo-Ortega, Santiago Villafaña   +9 more
doaj   +1 more source

Insilico targeting of virus entry facilitator NRP1 to block SARS-CoV2 entry.

PLoS ONE
The entry and infectivity of a virus are determined by its interaction with the host. SARS-CoV-2, the virus responsible for COVID-19, utilizes the spike (S) protein to attach to and enter host cells.
Nousheen Bibi, Maleeha Shah, Shahzad Khan, Muhammad Shahzad Chohan, Mohammad Amjad Kamal   +4 more
doaj   +1 more source

NRP1 is a Prognostic Factor and Promotes the Growth and Migration of Cells in Intrahepatic Cholangiocarcinoma

Cancer Management and Research, 2020
Yong-Na Wu,1– 4,* Li-Hong He,1,2,5,* Zhong-Tian Bai,1,2,5,* Xun Li1,2,5 1Department of General Surgery, The First Hospital of Lanzhou University, Lanzhou 730000, Gansu Province, People’s Republic of China; 2Key Laboratory of Biological ...
Wu YN, He LH, Bai ZT, Li X
doaj  

NRP1 interacts with endoglin and VEGFR2 to modulate VEGF signaling and endothelial cell sprouting

Communications Biology
Endothelial cells express neuropilin 1 (NRP1), endoglin (ENG) and vascular endothelial growth factor receptor 2 (VEGFR2), which regulate VEGF-A-mediated vascular development and angiogenesis.
Swati Sharma, Marcelo Ehrlich, Manqi Zhang, Gerard C. Blobe, Yoav I. Henis   +4 more
doaj   +1 more source

NRP1 Gene [PDF]

, 2020
openaire   +1 more source

Neuropilin 1 (NRP1) [PDF]

Science-Business eXchange, 2010
openaire   +1 more source

Radiation-induced YAP/TEAD4 binding confers non-small cell lung cancer radioresistance via promoting NRP1 transcription

Cell Death and Disease
Despite the importance of radiation therapy as a non-surgical treatment for non-small cell lung cancer (NSCLC), radiation resistance has always been a concern, due to poor patient response and prognosis.
Mingwei Wang, Junxuan Yi, Hui Gao, Xinfeng Wei, Weiqiang Xu, Mingqi Zhao, Mengdie Zhao, Yannan Shen, Zhicheng Wang, Ning Wu, Wei Wei, Shunzi Jin   +11 more
doaj   +1 more source

Neuropilin 1 (NRP1) [PDF]

Science-Business eXchange, 2009
openaire   +1 more source