Results 71 to 80 of about 15,068 (213)
Reduced SMC-specific Nrp1 expression in Nrp1SMKO.
, 2015 (A) qPCR analysis on the whole adult colon: means±SD, n = 3 ...
Maiko Yamaji (689767) +3 more
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Role of SoxE transcription factors in development and disease
Developmental Dynamics, EarlyView.Abstract Sox8, Sox9, and Sox10 arose by multiple rounds of genome duplications from a single SoxE gene in ancestral vertebrates. In this review, we will briefly discuss the molecular structure and function of SoxE transcription factors and their evolutionary origin. We will then discuss their expression, function, and developmental disorders.
Merin Lawrence, Gerhard Schlosser
wiley +1 more source
Image_7_STAT6 Upregulates NRP1 Expression in Endothelial Cells and Promotes Angiogenesis.tif
, 2022 The role of signal transducer and activator of transcription 6 (STAT6) in tumor growth has been widely recognized. However, its effects on the regulation of angiogenesis remain unclear.
Guanghui Ren (4229440) +3 more
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Elucidation of Potential NRP1 Interactors using BioID Technology [PDF]
Background: Neuropilin 1 (NRP1) is a transmembrane glycoprotein involved in diverse physiological processes, including angiogenesis, axonal guidance, immune regulation, cell adhesion, and recently, facilitation of SARS-CoV-2 entry and infectivity.
Coney, George
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Genetic status of KRAS modulates the role of Neuropilin-1 in tumorigenesis
Scientific Reports, 2017 Neuropilin-1 (NRP1), a non–tyrosine kinase receptor, is overexpressed in many cancers including pancreatic and lung cancers. Inhibition of NRP1 expression, however, has differing pro-tumor vs. anti-tumor effects, depending on the cancer types.
Sneha Vivekanandhan +6 more
doaj +1 more source
Mixed lineage kinase 3 mediates SARS‐CoV‐2‐induced kidney injury via the Hsp70‐IL‐17A axis
Interdisciplinary Medicine, EarlyView.Kidney samples from patients infected with severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) showed upregulated expression and activity of Mixed Lineage Kinase (MLK3). Based on the mechanistic studies, we identified MLK3 as a critical player in promoting SARS‐CoV‐2‐induced kidney injury.
Sandeep Kumar +18 more
wiley +1 more source
Overexpression of shRNA-resistant NRP1 and NRP2 rescues phenotype induced by NRP1 and NRP2 shRNA.
, 2013 Mixture of retrovirus expressing the indicated constructs was injected into dentate gyrus. Quantification of total dendritic length (A) and branch number (B) of newborn DGCs at 14 DPI.
Jae Ho Sohn (420043) +6 more
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iScience, 2019 Summary: The transmembrane protein neuropilin-1 (NRP1) promotes vascular endothelial growth factor (VEGF) and extracellular matrix signaling in endothelial cells (ECs).
Theo Issitt +8 more
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Journal of Applied Toxicology, EarlyView.ABSTRACT Monocrotaline (MCT), a plant‐derived pyrrolizidine alkaloid, is well known for its hepatotoxic effects. However, full elucidation of the mechanisms underlying MCT‐induced hepatotoxicity, as well as the development of reliable biomarkers for early detection and monitoring, requires an integrated evaluation of biochemical, molecular, and ...
Ali Şenol +4 more
wiley +1 more source
Gene expression profiles of Nrp1- and Nrp1+ Tfh cells.
, 2013 Nrp1- and Nrp1+ Tfh cells were sorted from 5 distinct tonsils and analyzed for gene expression as described in Materials and Methods. Gene expression (normalized to ACTB) of a selection of relevant transcription factors (A), cytokines and chemokines (B),
Julien Rossignol (221371) +7 more
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