Results 101 to 110 of about 15,799 (221)

Genomic-Scale Interaction Involving Complementary Sequences in the Hepatitis C Virus 5′UTR Domain IIa and the RNA-Dependent RNA Polymerase Coding Region Promotes Efficient Virus Replication

Viruses, 2018
The hepatitis C virus (HCV) genome contains structured elements thought to play important regulatory roles in viral RNA translation and replication processes.
Elodie Rance, Jerome E. Tanner, Caroline Alfieri   +2 more
doaj   +1 more source

Hcverso1 and 2: Faldaprevir with deleobuvir (BI 207127) and ribavirin for treatment-naïve patients with chronic hepatitis C virus genotype-1b infection [PDF]

, 2016
he interferon-free combination of once-daily faldaprevir 120 mg, twice-daily deleobuvir 600 mg, and weight-based ribavirin was evaluated in two Phase III studies (HCVerso1, HCVerso2) in hepatitis C virus genotype-1b-infected, treatment-naïve patients ...
Andreone, Pietro, Aslanyan, Stella, Buti, Maria, Calinas, Filipe, Castelli, Francesco, Colombo, Massimo, Deng, Qiqi, Kukolj, George, Mensa, Federico J., Nelson, David R., Olveira, Antonio, Pol, Stanislas, Puoti, Massimo, Roehrle, Michael, Sarrazin, Christoph, Shiffman, Mitchell, Stern, Jerry O., Vinisko, Richard   +17 more
core   +2 more sources

Cloning and Molecular Analysis of Hepatitis C Virus (HCV) 1a NS5B from HCV Isolated in Surakarta Indonesia [PDF]

, 2014
The hepatitis C virus (HCV) NS5B protein is known essential for virus replication and suggested play important role in therapy resistance mechanism. To predict and more understanding the molecular pattern of HCV 1a NS5B we cloned the NS5B gene of HCV 1a ...
Prasetyo, Afiono Agung
core  

A hepatitis C-vírus-bázispolimorfizmus jelentősége a kezelésben [PDF]

, 2015
Absztrakt A krónikus C-vírus hepatitis kezelése az elmúlt huszonöt évben igen jelentős fejlődésen ment keresztül.
Tornai, István
core   +1 more source

Immunogenicity of variable regions of hepatitis C virus proteins: selection and modification of peptide epitopes to assess hepatitis C virus genotypes by ELISA [PDF]

, 1999
The immunogenicity of variable regions of hepatitis C virus (HCV) proteins was studied by ELISA by using 543 synthetic peptides from 120 variable regions and 90 sera from HCV-infected patients.
Berasain, C. (Carmen), Borras-Cuesta, F. (Francisco), Civeira, M.P. (María Pilar), Prieto, J. (Jesús), Riezu-Boj, J.I. (José Ignacio), Rodriguez-Lopez, M. (Marta), Ruiz, M. (Marta)   +6 more
core  

High-resolution hepatitis C virus subtyping using NS5B deep sequencing and phylogeny, an alternative to current methods [PDF]

, 2015
HepatitisCvirus(HCV)is classified into seven major genotypesand67 subtypes. Recent studies haveshownthat inHCVgenotype 1-infected patients, response rates to regimens containingdirect-acting antivirals(DAAs)are subtype dependent.
Allende, Helena, Alvarez-Tejado, Miguel, Belmonte, Irene, Bes, Marta, Blasi, Maria, Briones, Carlos, Buti, Maria, Caballero, Andrea, Campo, Jose Antonio del, Casillas, Rosario, Castells, Lluis, Cubero, Maria, Domingo, Esteban, Esteban, Juan Ignacio, Esteban, Rafael, Forns, Xavier, Garcia-Cehic, Damir, Garcia-Samaniego, Javier, Gomez, Jordi, Gregori, Josep, Guardia, Jaume, Homs, Maria, Lens, Sabela, López-Rodríguez, Rosario, Madejon, Antonio, Moreno-Otero, Ricardo, Muñoz, Jose Manuel, Muñoz-de-Rueda, Paloma, Nieto, Leonardo, Perales, Celia, Perez-del-Pulgar, Sofia, Quer, Josep, Quiles-Pérez, Rosa, Rodríguez-Frias, Francisco, Romero-Gómez, Manuel, Ruiz-Extremera, Angela, Salmerón, Javier, Sanz-Cameno, Paloma, Sauleda, Silvia, Sheldon, Julie, Tabernero, David, Viladomiu, Lluis   +41 more
core   +2 more sources

Consideration of Viral Resistance for Optimization of Direct Antiviral Therapy of Hepatitis C Virus Genotype 1-Infected Patients.

PLoS ONE, 2015
Different highly effective interferon-free treatment options for chronic hepatitis C virus (HCV) infection are currently available. Pre-existence of resistance associated variants (RAVs) to direct antiviral agents (DAAs) reduces sustained virologic ...
Julia Dietz, Simone Susser, Caterina Berkowski, Dany Perner, Stefan Zeuzem, Christoph Sarrazin   +5 more
doaj   +1 more source

Molecular analysis of hepatitis C virus infection in Bulgarian injecting drug users [PDF]

, 2011
Intravenous drug users constitute a group at risk for hepatitis C virus (HCV) infection. Today, no data are available on the molecular epidemiology of HCV in Bulgaria despite the fact that in recent years the incidence of acute hepatitis C infection ...
Bogdanova, V, Cento, V, Ciccozzi, M, Ciotti, M, Pavlov, I, Perno, CF, Presti, AL, Teoharov, P, Zehender, G   +8 more
core   +4 more sources

Signals Involved in Regulation of Hepatitis C Virus RNA Genome Translation and Replication [PDF]

, 2018
Hepatitis C Virus (HCV) preferentially replicates in the human liver and frequently causes chronic infection, often leading to cirrhosis and liver cancer.
Gerresheim, Gesche K., Niepmann, Michael, Rossbach, Oliver, Shalamova, Lyudmila A.   +3 more
core   +1 more source

Comparison of Sanger sequencing for hepatitis C virus genotyping with a commercial line probe assay in a tertiary hospital

BMC Infectious Diseases, 2019
Background The technique most frequently used to genotype HCV is quantitative RT-PCR. This technique is unable to provide an accurate genotype/subtype for many samples; we decided to develop an in-house method with the goal of accurately identifying the ...
Sylvie Goletti, Siméon Zuyten, Léonie Goeminne, Chris Verhofstede, Hector Rodriguez-Villalobos, Monique Bodeus, Peter Stärkel, Yves Horsmans, Benoît Kabamba-Mukadi   +8 more
doaj   +1 more source