Results 161 to 170 of about 1,212,320 (287)

Cellular senescence in cancer : from mechanism paradoxes to precision therapeutics

open access: yes
202511 bcchVersion of RecordRGCOthersThis study is supported by the NSFC-RGC Joint Research Scheme (N_CUHK448/23), National Natural Science Foundation of China (NSFC) (2022, No.
Feng, T   +12 more
core   +1 more source

Molecular Editing Reveals a Bilobalide Chemotype that Attenuates Prolyl Endopeptidase (PREP)‐Linked Neuroinflammation

open access: yesAdvanced Science, EarlyView.
Molecular editing of bilobalide uncovers BB56, a PREP‐engaging chemotype with enhanced anti‐inflammatory activity in microglia. Integrated CETSA‐MS, SAR, and pathway analyses link BB56 to attenuation of p38 MAPK/NF‐κB and NLRP3‐associated inflammatory signaling, highlighting bilobalide editing as a strategy for developing neuroinflammation‐modulating ...
Chanin Sillapachaiyaporn   +20 more
wiley   +1 more source

Large-scale semidefinite programming with graphics processing units. [PDF]

open access: yesProc Natl Acad Sci U S A
Han Q   +6 more
europepmc   +1 more source

A supervised learning scheme for computing Hamilton-Jacobi equation via density coupling

open access: yes
202605 bcchVersion of RecordRGCOthersThe research is partially supported by research grants NSF DMS-2307465 and ONR N00014-21-1-2891. The research of the first author is partially supported by the Hong Kong Research Grant Council GRF grant 15302823, NSFC
Cui, J, Liu, S, Zhou, H
core   +1 more source

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

open access: yesAdvanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li   +7 more
wiley   +1 more source

Bound states in doped charge transfer insulators. [PDF]

open access: yesNat Commun
Li P   +5 more
europepmc   +1 more source

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