Results 71 to 80 of about 758,562 (308)

The current state and future prospects of the fundamental research on pediatric otorhinolaryngology: an analysis of application and funding data of the National Natural Science Foundation of China from 2009 to 2019

open access: yesAnnals of Translational Medicine, 2020
Background This study aimed to summarize the current situation and deficiencies of the fundamental research on pediatric otolaryngology-head and neck science.
Yihong Liu, Xiaobin Zhang
semanticscholar   +1 more source

A cascade model of information processing and encoding for retinal prosthesis

open access: yesNeural Regeneration Research, 2016
Retinal prosthesis offers a potential treatment for individuals suffering from photoreceptor degeneration diseases. Establishing biological retinal models and simulating how the biological retina convert incoming light signal into spike trains that can ...
Zhi-jun Pei   +4 more
doaj   +1 more source

Kalman Filtering for Discrete Stochastic Systems with Multiplicative Noises and Random Two-Step Sensor Delays

open access: yes, 2015
This work was supported in part by the National Natural Science Foundation of China (NSFC) under Grants 11271103 and 11301118.
Dongyan Chen   +3 more
semanticscholar   +1 more source

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

open access: yesMolecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh   +5 more
wiley   +1 more source

Biodegradable chitin conduit tubulation combined with bone marrow mesenchymal stem cell transplantation for treatment of spinal cord injury by reducing glial scar and cavity formation

open access: yesNeural Regeneration Research, 2015
We examined the restorative effect of modified biodegradable chitin conduits in combination with bone marrow mesenchymal stem cell transplantation after right spinal cord hemisection injury.
Feng Xue   +6 more
doaj   +1 more source

Establishment and optimization of the two‐step induction system for generating primordial germ cell‐like cells from chicken embryonic stem cells

open access: yesFEBS Open Bio, EarlyView.
This study optimizes a two‐step induction system to generate PGCLCs from chicken ESCs. The induced cells express germline markers and migrate to gonads in ovo, offering a novel approach for avian genetic resource conservation. Primordial germ cells (PGCs) are the progenitor cells of sperm and eggs.
Zeyu Li   +10 more
wiley   +1 more source

Expression pattern of neuregulin-1 type III during the development of the peripheral nervous system

open access: yesNeural Regeneration Research, 2015
Neuregulin-1 type III is a key regulator in Schwann cell proliferation, committing to a myelinating fate and regulating myelin sheath thickness.
Liang-liang Huang   +3 more
doaj   +1 more source

Loss of Stat3 in Prx1+ Progenitors Impairs Molar Root Development

open access: yesAdvanced Biology, EarlyView.
Stat3 critically regulates mandibular first molar and alveolar bone morphogenesis. Conditional ablation of Stat3 disrupts the osteogenic capacity of Prx1+ mesenchymal progenitors, as evidenced across in vivo and in vitro models. Abstract Signal Transducer and Activator of Transcription 3 (Stat3) acts as a central transcriptional modulator coordinating ...
Xin Feng   +10 more
wiley   +1 more source

Constraint-induced movement therapy promotes motor function recovery and downregulates phosphorylated extracellular regulated protein kinase expression in ischemic brain tissue of rats

open access: yesNeural Regeneration Research, 2015
Motor function impairment is a common outcome of stroke. Constraint-induced movement therapy (CIMT) involving intensive use of the impaired limb while restraining the unaffected limb is widely used to overcome the effects of ′learned non-use′ and improve
Bei Zhang   +6 more
doaj   +1 more source

A Family of Binary Sequences with 4-Valued Optimal Out-of-Phase Correlation and Large Linear Span [PDF]

open access: yesIEICE Transactions on Fundamentals of Electronics, Communications and Computer Sciences, 2006
In this paper, a new family (r) of 2n binary sequences of period 2n-1 is proposed, where n≡2 mod 4 and gcd (r, 2n/2-1)=1. The presented family takes 4-valued out-of-phase auto- and cross-correlation values -1, ±2n/2-1, and 2n/2+1-1, and its correlation distribution is determined.
Lei Hu, Xiangyong Zeng, Wenfeng Jiang
openaire   +2 more sources

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