Results 101 to 110 of about 4,073 (199)

β‐Lactamase‐Producing Haemophilus influenzae Pneumonia in a 1‐Month‐Old Infant With Respiratory Syncytial Virus Bronchiolitis

Journal of General and Family Medicine, Volume 27, Issue 3, May 2026.
Kazumasa Zensho, Naoki Nojima, Ryoma Hino, Naohi Isse   +3 more
wiley   +1 more source

Microsatellite Instability in the Tumor Microenvironment: The Role of Inflammation and the Microbiome

Cancer Medicine, Volume 14, Issue 8, April 2025.
The microbiome, an environmental factor, can contribute to DNA damage and affect mutation accumulation. Infections with genotoxin‐producing pathobionts can induce inflammation and oxidative stress through reactive nitrogen and oxygen species, which may influence MSI.
Elizabeth Vargas‐Castellanos, Andrés Rincón‐Riveros   +1 more
wiley   +1 more source

Cytokine secretion in murine macrophages after stimulation with non-viable NTHi. [PDF]

, 2013
Murine macrophages were stimulated with inactivated NTHi for 24 h. IL-1β concentrations were significantly reduced compared to stimulation with viable NTHi (A).
Peter Kujath (427192), Torsten Goldmann (427193), Kristina Rohmann (427190), Jan Rupp (36913), Johannes Rotta detto Loria (427189), Klaus Dalhoff (262716), Daniel Droemann (427191)   +6 more
core   +1 more source

Beyond the Toll‐Like Receptor 4. Structure‐Dependent Lipopolysaccharide Recognition Systems: How far are we?

ChemMedChem, Volume 20, Issue 6, March 15, 2025.
This review goes beyond the famous MD‐2/TLR4‐mediated recognition of LPS, pointing the attention on other immune detection systems and their impact on human physiology and pathology. Understanding these additional pathways is key for the development of pharmacologically active molecules to modulate the immune response and to conceive new strategies to ...
Stefania De Chiara, Luca De Simone Carone, Roberta Cirella, Emanuela Andretta, Alba Silipo, Antonio Molinaro, Marcello Mercogliano, Flaviana Di Lorenzo   +7 more
wiley   +1 more source

MKK3/6-p38 mediates EGFR-dependent inflammation induced by NTHi in middle ear epithelial cells. [PDF]

, 2013
(A) Cells were incubated with NTHi with or without SB203580, and NTHi-induced NF-κB activation was measured by performing luciferase assay. (B) Cells were incubated with NTHi with or without SB203580, and mRNA expression of TNF-α, IL-1β and IL-8 was ...
Xiangbin Xu (338925), Jian-Dong Li (35211), Jae Hyang Lim (35202), Sanjay B. Maggirwar (244853), Jinjiang Pang (338931), Christine A. Fedorchuk (338929), Zhixing K. Pan (338932), Haidong Xu (35210), Rachel R. Steere (338927), Ji-Yun Lee (230138)   +9 more
core   +1 more source

Finite Lattices Generating Not Finitely–Based and Nonstandard Quasivarieties

Journal of Mathematics, Volume 2025, Issue 1, 2025.
There are two well‐known and closely related problems in lattice theory: Which finite lattices generate finitely‐based quasivarieties? and Which finite lattices generate standard quasivarieties? The main goal of the paper is to contribute to both problems.
M. A. Arapbay, A. O. Basheyeva, S. M. Lutsak, Ljubisa Kocinac   +3 more
wiley   +1 more source

RV infection prolongs lung inflammation caused by NTHi and suppresses initial chemokine response. [PDF]

, 2012
Mice were infected with sham or RV followed by NTHi as described in Figure 1. (A and B) Hematoxylin and eosin stained lung sections from Sham/NTHi-infected mice at 1 and 3 days post NTHi infection respectively. (C to E) Hematoxylin and eosin stained lung
Benjamin L. Unger (130418), Andrea N. Faris (130419), Umadevi S. Sajjan (130425), Marc B. Hershenson (130424), Adam T. Comstock (130423), Shyamala Ganesan (130421)   +5 more
core   +1 more source

Species‐level, metagenomic and proteomic analysis of microbe‐immune interactions in severe asthma

Allergy, Volume 79, Issue 11, Page 2966-2980, November 2024.
Paired long‐read metagenomic sequencing and proteomics in sputum and nasal lavage identified a single dominant respiratory pathogen (H. influenzae more than M. catarrhalis and S. pneumoniae) in 23% of severe asthma sputum samples. Nasal and sputum microbiomes were highly discordant. H.
Maisha F. Jabeen, Nicholas D. Sanderson, Mariaenrica Tinè, Gillian Donachie, Clair Barber, Adnan Azim, Laurie C. K. Lau, Thomas Brown, Ian D. Pavord, Anoop Chauhan, Paul Klenerman, Teresa L. Street, Emanuele Marchi, Peter H. Howarth, Timothy S. C. Hinks   +14 more
wiley   +1 more source

Nontypeable Haemophilus influenzae induces COX-2 and PGE2 expression in lung epithelial cells via activation of p38 MAPK and NF-kappa B

Respiratory Research, 2008
Background Nontypeable Haemophilus influenzae (NTHi) is an important respiratory pathogen implicated as an infectious trigger in chronic obstructive pulmonary disease, but its molecular interaction with human lung epithelial cells remains unclear. Herein,
Koga Tomoaki, Lim Jae-Hyang, Wu Zuqun, Zhang Rong, Xu Zhihao, Xu Feng, Li Jian-Dong, Shen Huahao   +7 more
doaj   +1 more source

Activation of Epidermal Growth Factor Receptor Is Required for NTHi-Induced NF-κB-Dependent Inflammation

PLoS ONE, 2011
Inflammation is a hallmark of many serious human diseases. Nontypeable Haemophilus influenzae (NTHi) is an important human pathogen causing respiratory tract infections in both adults and children. NTHi infections are characterized by inflammation, which is mainly mediated by nuclear transcription factor-kappa B (NF-κB)-dependent production of ...
Xiangbin Xu, Rachel R Steere, Christine A Fedorchuk, Jinjiang Pang, Ji-Yun Lee, Jae Hyang Lim, Haidong Xu, Zhixing K Pan, Sanjay B Maggirwar, Jian-Dong Li   +9 more
openaire   +4 more sources