Results 81 to 90 of about 6,848 (195)

Antagonism of miR-328 Increases the Antimicrobial Function of Macrophages and Neutrophils and Rapid Clearance of Non-typeable Haemophilus Influenzae (NTHi) from Infected Lung

PLoS Pathogens, 2015
Pathogenic bacterial infections of the lung are life threatening and underpin chronic lung diseases. Current treatments are often ineffective potentially due to increasing antibiotic resistance and impairment of innate immunity by disease processes and ...
Hock L. Tay, G. Kaiko, M. Plank, Jing-Jing Li, S. Maltby, A. Essilfie, A. Jarnicki, Ming Yang, J. Mattes, P. Hansbro, P. Foster   +10 more
semanticscholar   +1 more source

Detection of Diagnostic Antibodies in Immune‐Mediated Diseases: A Focus on Antigens and Technologies

ChemBioChem, Volume 27, Issue 9, 14 May 2026.
This review explores autoantibody detection in immune‐mediated diseases, highlighting autoantigens including post‐translational modifications. We compared enzyme‐linked immunosorbent assay and indirect immunofluorescence with automated chemiluminescence platforms.
Silvia Bracci, Feliciana Real‐Fernandez, Federico Pratesi, Francesca Nuti, Paolo Rovero, Anna Maria Papini   +5 more
wiley   +1 more source

CYLD inhibits NTHi-induced activation of ERK.

, 2014
(A–B) Cells transfected with (A) CYLD WT or (B) siCYLD were stimulated with NTHi for 30 min, and cell lysates were analyzed by immunoblotting with the indicated antibodies (upper panel).
Kensei Komatsu (659352), Yuxian Huang (381470), Jian-Dong Li (35211), Wenhong Zhang (207387), Masanori Miyata (659353), Jing Wu (54032), Haidong Xu (35210), Wenzhuo Y. Wang (659351), Ji-Yun Lee (230138)   +8 more
core   +1 more source

Effects of repeated infections with non-typeable Haemophilus influenzae on lung in vitamin D deficient and smoking mice

Respiratory Research, 2022
Background In chronic obstructive pulmonary disease (COPD), exacerbations cause acute inflammatory flare-ups and increase the risk for hospitalization and mortality.
Jef Serré, Ajime Tom Tanjeko, Carolien Mathyssen, Tobias Heigl, Annelore Sacreas, Dana Paulina Cook, Erik Verbeken, Karen Maes, Jan Verhaegen, Charles Pilette, Jeroen Vanoirbeek, Conny Gysemans, Chantal Mathieu, Bart Vanaudenaerde, Wim Janssens, Ghislaine Gayan-Ramirez   +15 more
doaj   +1 more source

Epidemiology and antimicrobial susceptibility of non-typeable Haemophilus influenzae in otitis media in Taiwanese children

Journal of Microbiology, Immunology and Infection, 2019
Background: Concerns about non-typeable Haemophilus influenzae (NTHi) in otitis media (OM) have grown after the introduction of pneumococcal conjugate vaccine (PCV). We aim to better understand the clinical role of NTHi in pediatric OM.
Ying-Chun Cho, Nan-Chang Chiu, Fu-Yuan Huang, Daniel Tsung-Ning Huang, Lung Chang, Ching-Ying Huang, Yen-Hsin Kung, Kuo-Sheng Lee, Hsin Chi   +8 more
doaj   +1 more source

Incidence of Cefotaxime‐Resistant Haemophilus influenzae Is Linked to Regional Consumption of Oral Aminopenicillins and Parenteral Third‐Generation Cephalosporins in Norway

APMIS, Volume 134, Issue 4, April 2026.
ABSTRACT The emergence of cefotaxime‐resistant Haemophilus influenzae (CRHI) in Norway during the 2000s coincided with increased use of oral aminopenicillins and parenteral third‐generation cephalosporins. This study examined associations between beta‐lactam consumption and CRHI incidence. Surveillance data on antibiotic usage across Norwegian regions (
Dagfinn Skaare, Gunnar Skov Simonsen
wiley   +1 more source

The impact of Ecrg4 over-expression on ME inflammation after NTHi infection in vivo.

, 2013
Panel A: RT-PCR shows the relative Ecrg4 gene expression in ME mucosal tissue 4 days after AD injection into the ME in vivo and 48 hrs post-infection.
Allen F. Ryan (405683), Brian P. Eliceiri (344173), Arwa Kurabi (344167), Xitong Dang (344164), Kwang Pak (405682), Andrew Baird (344174), Raul Coimbra (344171)   +6 more
core   +1 more source

Extracellular DNA and Type IV Pilus Expression Regulate the Structure and Kinetics of Biofilm Formation by Nontypeable Haemophilus influenzae

mBio, 2017
Biofilms formed in the middle ear by nontypeable Haemophilus influenzae (NTHI) are central to the chronicity, recurrence, and refractive nature of otitis media (OM).
Jayajit Das, Elaine Mokrzan, Vinal Lakhani, Lucia Rosas, Joseph A. Jurcisek, William C. Ray, Lauren O. Bakaletz   +6 more
doaj   +1 more source

Exploring microorganism–host interactions: Emerging organoid models and analytical approaches

mLife, Volume 5, Issue 1, Page 17-34, February 2026.
Abstract Microorganisms play a vital role in human health through their interactions with the body. Studies of host–microbe mechanisms and interactions are crucial for advancing health management. Recently, the organoid‐based models have provided new platforms in this field.
Yue Shi, Min Xu, Yanhong Huang, Jing Qu, Shumin Liao, Yingzi Liu, Liang Li   +6 more
wiley   +1 more source

Molecular characterization of multidrug-resistant non-typeable Haemophilus influenzae with high-level resistance to cefuroxime, levofloxacin, and trimethoprim-sulfamethoxazole

BMC Microbiology, 2023
Background Non-typeable Haemophilus influenzae (NTHi) has become the major cause of invasive H. influenzae diseases in the post-H. influenzae type b vaccine era. The emergence of multidrug-resistant (MDR) NTHi is a growing public health problem.
Pei-Yi Su, Wei-Hung Cheng, Cheng-Hsun Ho
doaj   +1 more source