Results 81 to 90 of about 4,073 (199)

Epidemiology and antimicrobial susceptibility of non-typeable Haemophilus influenzae in otitis media in Taiwanese children

Journal of Microbiology, Immunology and Infection, 2019
Background: Concerns about non-typeable Haemophilus influenzae (NTHi) in otitis media (OM) have grown after the introduction of pneumococcal conjugate vaccine (PCV). We aim to better understand the clinical role of NTHi in pediatric OM.
Ying-Chun Cho, Nan-Chang Chiu, Fu-Yuan Huang, Daniel Tsung-Ning Huang, Lung Chang, Ching-Ying Huang, Yen-Hsin Kung, Kuo-Sheng Lee, Hsin Chi   +8 more
doaj   +1 more source

Effects of repeated infections with non-typeable Haemophilus influenzae on lung in vitamin D deficient and smoking mice

Respiratory Research, 2022
Background In chronic obstructive pulmonary disease (COPD), exacerbations cause acute inflammatory flare-ups and increase the risk for hospitalization and mortality.
Jef Serré, Ajime Tom Tanjeko, Carolien Mathyssen, Tobias Heigl, Annelore Sacreas, Dana Paulina Cook, Erik Verbeken, Karen Maes, Jan Verhaegen, Charles Pilette, Jeroen Vanoirbeek, Conny Gysemans, Chantal Mathieu, Bart Vanaudenaerde, Wim Janssens, Ghislaine Gayan-Ramirez   +15 more
doaj   +1 more source

The Burden of Respiratory Syncytial Virus in Children With Acute Otitis Media: A Systematic Review and Meta‐Analysis

Influenza and Other Respiratory Viruses, Volume 20, Issue 2, February 2026.
ABSTRACT Background Acute otitis media (AOM) affects over 709 million individuals globally each year, more than half of whom are children < 5 years. Respiratory syncytial virus (RSV) is a leading viral cause of pediatric respiratory illness. We aimed to estimate the burden of RSV in children < 5 years with AOM Methods We performed a systematic review ...
Sebastien Kenmoe, Marshall Dozier, Jingyi Liang, Ruth Jenkins, Harish Nair   +4 more
wiley   +1 more source

[Nontypeable Haemophilus influenzae (NTHi) epidemiology].

Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases, 2011
While most systemic pediatric Haemophilus influenzae infections are caused by the type b strain (Hib), nontypeable H. influenzae: (NTHi) has been considered a respiratory tract pathogen common in local infection such as acute otitis media, acute pneumonia, secondary chronic respiratory disease and other otorhinolaryngologic infections.
Keisuke, Sunakawa, Yuriko, Takeuchi, Satoshi, Iwata   +2 more
openaire   +1 more source

SuperSILAC Quantitative Proteome Profiling of Murine Middle Ear Epithelial Cell Remodeling with NTHi

PLOS ONE, 2016
Chronic Otitis Media with effusion (COME) develops after sustained inflammation and is characterized by secretory middle ear epithelial metaplasia and effusion, most frequently mucoid. Non-typeable Haemophilus influenzae (NTHi), the most common acute Otitis Media (OM) pathogen, is postulated to promote middle ear epithelial remodeling in the ...
Stéphanie Val, Katelyn Burgett, Kristy J Brown, Diego Preciado   +3 more
openaire   +4 more sources

Strain-dependent effects of Nontypeable Haemophilus influenzae (NTHi) on human macrophage function [PDF]

, 2019
Nontypeable Haemophilus influenzae (NTHi) is a heterogeneous respiratory tract pathogen implicated in opportunistic infections and exacerbations of chronic respiratory diseases, such as COPD and asthma. In these diseases, airway macrophages have impaired
Jodie Ackland, Karl Staples, Christodoulides, Myron, Wilkinson, Tom, Myron Christodoulides, Tom Wilkinson, David Cleary, Cleary, David; id_orcid, Ackland, Jodie, Cleary, David, Staples, Karl   +10 more
core   +1 more source

Considerations for the Use of Brain Endurance Training in Elite Sport: A Narrative Review

Scandinavian Journal of Medicine &Science in Sports, Volume 36, Issue 2, February 2026.
ABSTRACT Brain endurance training (BET) has been proposed as a method to enhance resistance to mental fatigue (MF) and mitigate the negative effects of MF on performance. The use of BET has been associated with improvements in endurance performance, cognitive function, skill performance, and reduced perception of effort under conditions of MF in ...
Sam D. Joseph, Suzanna Russell, Paul J. Tofari, Shona L. Halson, Rich D. Johnston, Ryan G. Timmins, Nick B. Murray, Stuart J. Cormack   +7 more
wiley   +1 more source

3D Reconstruction of the Human Airway Mucosa In Vitro as an Experimental Model to Study NTHi Infections

PLOS ONE, 2016
We have established an in vitro 3D system which recapitulates the human tracheo-bronchial mucosa comprehensive of the pseudostratified epithelium and the underlying stromal tissue. In particular, we reported that the mature model, entirely constituted of primary cells of human origin, develops key markers proper of the native tissue such as the ...
MARRAZZO, PASQUALE, Maccari, Silvia, Taddei, Annarita, Bevan, Luke, Telford, John, Soriani, Marco, Pezzicoli, Alfredo   +6 more
openaire   +4 more sources

TLR-TRAF6-dependent synergistic MUC5AC induction by NTHi and PMA is mediated by PKCθ. [PDF]

, 2013
(A) Rottlerin, a specific PKC™/θ inhibitor, blocked the synergistic induction of MUC5AC transcription by NTHi and PMA in human epithelial cells, as assessed by MUC5AC-dependent promoter Luciferase assay.
Hirofumi Jono (35203), Jian-Dong Li (35211), Jae Hyang Lim (35202), Haidong Xu (35210)   +3 more
core   +1 more source

Dietary flavanols preserve upper‐ and lower‐limb endothelial function during sitting in high‐ and low‐fit young healthy males

The Journal of Physiology, Volume 604, Issue 1, Page 145-171, 1 January 2026.
Abstract figure legend Schematic indicating the design of an acute randomised, counterbalanced, double‐blinded, cross‐over, placebo‐controlled human study in which 20 high‐fit males and 20 low‐fit males consumed either a low‐flavanol (5.6 mg) or a high‐flavanol (695 mg) cocoa drink prior to a 2 h uninterrupted sitting bout.
Alessio Daniele, Samuel J. E. Lucas, Catarina Rendeiro   +2 more
wiley   +1 more source