Results 61 to 70 of about 4,073 (199)

Modulation of Haemophilus influenzae interaction with hydrophobic molecules by the VacJ/MlaA lipoprotein impacts strongly on its interplay with the airways

open access: yesScientific Reports, 2018
Airway infection by nontypeable Haemophilus influenzae (NTHi) associates to chronic obstructive pulmonary disease (COPD) exacerbation and asthma neutrophilic airway inflammation.
Ariadna Fernández-Calvet   +14 more
doaj   +1 more source

NTHi infection suppressed key features of Th2-driven eosinophilic AAD. [PDF]

open access: yes, 2013
Groups of mice were infected during (d0 NTHi+OVA) or 10 days after (d10 NTHi+OVA) OVA sensitization (A), and AAD was analyzed (on day 16). The effects of infection on IL-5, IL-13, and IFN-γ (B) release from MLN T cells stimulated with OVA, BALF total ...
Peter G. Gibson (88654)   +7 more
core   +1 more source

Research on the Mechanism of Natural Products Acting on Chronic Obstructive Pulmonary Disease

open access: yesFood Science &Nutrition, Volume 14, Issue 7, July 2026.
This figure illustrates that approximately 80 natural compounds exert therapeutic effects against chronic obstructive pulmonary disease by targeting pathological mechanisms such as airway inflammation, oxidative stress, airway remodeling, mucus hypersecretion, emphysema, protease–antiprotease imbalance, apoptosis, and autophagy.
Shuna Wei, Xiaoju Liu
wiley   +1 more source

Rhinovirus attenuates non-typeable Hemophilus influenzae-stimulated IL-8 responses via TLR2-dependent degradation of IRAK-1. [PDF]

open access: yesPLoS Pathogens, 2012
Bacterial infections following rhinovirus (RV), a common cold virus, are well documented, but pathogenic mechanisms are poorly understood. We developed animal and cell culture models to examine the effects of RV on subsequent infection with non-typeable ...
Benjamin L Unger   +5 more
doaj   +1 more source

Nocturnal Cerebral Oxygenation in Low‐Altitude Residents With Pulmonary Vascular Disease Staying Overnight at High Altitude. Data From a Randomized, Controlled, Crossover Trial

open access: yesPulmonary Circulation, Volume 16, Issue 3, July 2026.
ABSTRACT Whether hypoxia during popular high‐altitude travel negatively affects cerebral oxygenation in vulnerable patients with pulmonary vascular disease (PVD) is unknown. We studied overnight cerebral tissue oxygen saturation (CTO) and desaturation index (cODI) in PVD‐patients at 2500 m and effects of supplemental oxygen therapy (SOT).
Carolin Kränzle   +15 more
wiley   +1 more source

Haemophilin-producing strains of Haemophilus haemolyticus protect respiratory epithelia from NTHi colonisation and internalisation [PDF]

open access: yes, 2021
Nontypeable Haemophilus influenzae (NTHi) is a significant respiratory tract pathogen responsible for infections that collectively pose a substantial health and socioeconomic burden.
David Gell (14737321)   +3 more
core   +3 more sources

Oropharyngeal Carriage of hpl-Containing Haemophilus haemolyticus Predicts Lower Prevalence and Density of NTHi Colonisation in Healthy Adults

open access: yesPathogens, 2021
Nontypeable Haemophilus influenzae (NTHi) is a major respiratory pathogen that initiates infection by colonising the upper airways. Strategies that interfere with this interaction may therefore have a clinically significant impact on the ability of NTHi ...
Brianna Atto   +3 more
doaj   +1 more source

Cerebral oxygenation and skeletal muscle responses to time trial, maximal oxygen uptake and time to exhaustion exercise

open access: yesExperimental Physiology, Volume 111, Issue 7, Page 3267-3279, 1 July 2026.
Abstract This study investigated cerebral and neuromuscular responses to three exercise models: time trial (TT), maximal oxygen uptake (V̇O2max${{\dot{V}}_{{{{\mathrm{O}}}_2}{\mathrm{max}}}}$) and time to exhaustion (TTE). Fourteen participants completed the tests in the following order: V̇O2max${{\dot{V}}_{{{{\mathrm{O}}}_2}{\mathrm{max}}}}$, TT and ...
Caroline V. Robertson   +3 more
wiley   +1 more source

PMA synergistically enhances TLR-dependent MUC5AC induction by NTHi via TRAF6. [PDF]

open access: yes, 2013
(A) PMA synergistically enhanced NTHi-induced polyubiquitination of TRAF6 in human epithelial cells. Cells were transfected with TRAF6, and were treated with NTHi and PMA as indicated.
Hirofumi Jono (35203)   +3 more
core   +1 more source

Detection of Diagnostic Antibodies in Immune‐Mediated Diseases: A Focus on Antigens and Technologies

open access: yesChemBioChem, Volume 27, Issue 9, 14 May 2026.
This review explores autoantibody detection in immune‐mediated diseases, highlighting autoantigens including post‐translational modifications. We compared enzyme‐linked immunosorbent assay and indirect immunofluorescence with automated chemiluminescence platforms.
Silvia Bracci   +5 more
wiley   +1 more source

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