Results 51 to 60 of about 6,848 (195)

Total and NTHi-specific IgG1 are decreased in BAL from NTHi+ve patients.

, 2016
Total (A) serum IgG1, (B) serum IgG2 (C) serum IgG3 was analysed by MSD multiplex assay. Total (D) IgG1, (E) IgG2 and (F) IgG3 in BAL derived from two lung lobes were analysed by MSD multiplex assay and the average concentration from both lobes is ...
Stephanie Leung (3368846), Tom M. A. Wilkinson (702971), Kristoffer Ostridge (3368855), Stuart C. Clarke (415927), Andrew Gorringe (3368852), Andrew C. Tuck (3368843), Thierry G. Pascal (3368849), Karl J. Staples (457228), Stephen Taylor (81177), Steve Thomas (11698), Karen Cox (67096), Lindsay Welch (3368858)   +11 more
core   +1 more source

Resveratrol suppresses NTHi-induced inflammation via up-regulation of the negative regulator MyD88 short

Scientific Reports, 2016
Upper respiratory tract inflammatory diseases such as asthma and chronic obstructive pulmonary diseases (COPD) affect more than one-half billion people globally and are characterized by chronic inflammation that is often exacerbated by respiratory ...
Carla S. Andrews, S. Matsuyama, Byung-Cheol Lee, Jian-Dong Li   +3 more
semanticscholar   +1 more source

The roles of phosphocholine expressed on NTHi bacteria and host CRP in acute otitis media

, 2023
Otitis Media (OM) is inflammation of the middle ear (ME). Non-typeable Haemophilus influenzae (NTHi) is one of the leading otopathogens causing OM. Phosphocholine (PCho) on the NTHi lipopolysaccharide influences host-pathogen interaction.
Bharj, Gurpreet
core   +1 more source

Modulation of Haemophilus influenzae interaction with hydrophobic molecules by the VacJ/MlaA lipoprotein impacts strongly on its interplay with the airways

Scientific Reports, 2018
Airway infection by nontypeable Haemophilus influenzae (NTHi) associates to chronic obstructive pulmonary disease (COPD) exacerbation and asthma neutrophilic airway inflammation.
Ariadna Fernández-Calvet, Irene Rodríguez-Arce, Goizeder Almagro, Javier Moleres, Begoña Euba, Lucía Caballero, Sara Martí, José Ramos-Vivas, Toby Leigh Bartholomew, Xabier Morales, Carlos Ortíz-de-Solórzano, José Enrique Yuste, José Antonio Bengoechea, Raquel Conde-Álvarez, Junkal Garmendia   +14 more
doaj   +1 more source

Invasive non-typeable Haemophilus influenzae infection due to endometritis associated with adenomyosis

BMC Infectious Diseases, 2020
Background The widespread administration of the Haemophilus influenzae type b vaccine has led to the predominance of non-typable H. influenzae (NTHi). However, the occurrence of invasive NTHi infection based on gynecologic diseases is still rare.
Yoshito Nishimura, Hideharu Hagiya, Kaoru Kawano, Yuya Yokota, Kosuke Oka, Koji Iio, Kou Hasegawa, Mikako Obika, Tomoko Haruma, Sawako Ono, Hisashi Masuyama, Fumio Otsuka   +11 more
doaj   +1 more source

Adaptive (72 hour) cytokine production to NTHi.

, 2014
a) In vitro cytokine production by HC (open circles) and CSLD (filled circles) PBMC following 72 hour challenge with NTHi. Delta concentration (NTHi challenge minus nil challenge) with median and IQR.
John W. Upham (136259), Belinda J. Hales (356792), Anne B. Chang (441913), Susan J. Pizzutto (613119), Stephanie T. Yerkovich (107950), Wayne R. Thomas (299396)   +5 more
core   +1 more source

Curcumin Inhibits NTHi-Induced MUC5AC Mucin Overproduction in Otitis Media via Upregulation of MAPK Phosphatase MKP-1

International Journal of Inflammation, 2017
Otitis media (OM), characterized by the presence of mucus overproduction and excess inflammation in the middle ear, is the most common childhood infection.
Anuhya S. Konduru, S. Matsuyama, Byung-Cheol Lee, Kensei Komatsu, Jian-Dong Li   +4 more
semanticscholar   +1 more source

NTHi infection induces neutrophilic inflammation in AAD.

, 2013
The effect of NTHi infection on BALF neutrophil numbers in AAD was determined (on day 16) and compared to groups with AAD without infection or infection alone without AAD.
Peter G. Gibson (88654), Jodie L. Simpson (342568), Ama-Tawiah Essilfie (313146), Paul S. Foster (157707), Julie A. Preston (150469), Philip M. Hansbro (157715), Margaret L. Dunkley (342569), Jay C. Horvat (157694)   +7 more
core   +1 more source

Rhinovirus attenuates non-typeable Hemophilus influenzae-stimulated IL-8 responses via TLR2-dependent degradation of IRAK-1. [PDF]

PLoS Pathogens, 2012
Bacterial infections following rhinovirus (RV), a common cold virus, are well documented, but pathogenic mechanisms are poorly understood. We developed animal and cell culture models to examine the effects of RV on subsequent infection with non-typeable ...
Benjamin L Unger, Andrea N Faris, Shyamala Ganesan, Adam T Comstock, Marc B Hershenson, Umadevi S Sajjan   +5 more
doaj   +1 more source

Phase I, randomized, observer-blind, placebo-controlled studies to evaluate the safety, reactogenicity and immunogenicity of an investigational non-typeable Haemophilus influenzae (NTHi) protein vaccine in adults.

Vaccine, 2016
BACKGROUND Non-typeable Haemophilus influenzae (NTHi) is a major cause of various respiratory diseases. The development of an effective vaccine against NTHi mandates new approaches beyond conjugated vaccines as this opportunistic bacterium is non ...
G. Leroux-Roels, P. van Damme, W. Haazen, S. Shakib, Magalie Caubet, E. Aris, J. Devaster, M. Peeters   +7 more
semanticscholar   +1 more source