Results 51 to 60 of about 4,073 (199)
Western Blot analysis of inflammasome components after stimulation with NTHi. [PDF]
, 2013 A+B show caspase-1 (A) and NLRP3 (B) expression over a period of 6 h after stimulation with NTHi 106 cfu/ml in murine macrophages. NLRP3 was detected in murine macrophages after stimulation with inactivated NTHi as well (C).
Peter Kujath (427192) +6 more
core +1 more source
CYLD inhibits NTHi-induced activation of ERK. [PDF]
, 2014 (A–B) Cells transfected with (A) CYLD WT or (B) siCYLD were stimulated with NTHi for 30 min, and cell lysates were analyzed by immunoblotting with the indicated antibodies (upper panel).
Kensei Komatsu (659352) +8 more
core +1 more source
Characterization of NTHi infection. [PDF]
, 2013 The profile of infection was assessed in mice that only received NTHi (i.e. not OVA), by performing a time-course of bacterial recovery from BALF and lung homogenates (A), and airway inflammation represented by BALF neutrophils, lymphocytes and ...
Peter G. Gibson (88654) +7 more
core +1 more source
Frontiers in Cellular and Infection Microbiology, 2023 Non-typeable Haemophilus influenzae (NTHi) is a Gram-negative human pathogen that causes a wide range of airway diseases. NTHi has a plethora of mechanisms to colonize while evading the host immune system for the establishment of infection. We previously
Yu-Ching Su +11 more
doaj +1 more source
Selective Capture of Anti‐N‐glucosylated NTHi Adhesin Peptide Antibodies by a Multivalent Dextran Conjugate [PDF]
ChemBioChem, 2021 AbstractTentacle‐like polymers decorated with several copies of peptide antigens can be interesting tools for increasing the ability to capture circulating antibodies in patient sera, using cooperative effects for stronger avidity. We previously showed that antibodies from multiple sclerosis (MS) patient sera preferentially recognize hyperglucosylated ...
Mazzoleni, Antonio +9 more
openaire +4 more sources
The impact of Ecrg4 over-expression on ME inflammation after NTHi infection in vivo. [PDF]
, 2013 Panel A: RT-PCR shows the relative Ecrg4 gene expression in ME mucosal tissue 4 days after AD injection into the ME in vivo and 48 hrs post-infection.
Allen F. Ryan (405683) +6 more
core +1 more source
Frontiers in Immunology, 2019 Non-typeable Haemophilus influenzae (NTHi) causes persistent respiratory infections in patients with chronic obstructive pulmonary disease (COPD), probably linked to its capacity to invade and reside within pneumocytes.
Belén García-Fojeda +14 more
doaj +1 more source
Epithelial immune activation and intracellular invasion by non-typeable Haemophilus influenzae
Frontiers in Cellular and Infection Microbiology, 2023 Type-2 low asthma affects 30-50% of people with severe asthma and includes a phenotype characterized by sputum neutrophilia and resistance to corticosteroids. Airways inflammation in type-2 low asthma or COPD is potentially driven by persistent bacterial
Mary A. Brown +6 more
doaj +1 more source
MiR-328 is down-regulated after NTHi infection. [PDF]
, 2015 (A) NTHi clearance from the lungs. Mice were inoculated i.t. with 5x105 CFU of NTHi. Bacterial load as assessed by bacterial colony counts from lung homogenates. (B) Total cells in BAL fluid following NTHi challenge.
Gerard E. Kaiko (221965) +10 more
core +1 more source
BMC Infectious Diseases, 2020 Background The widespread administration of the Haemophilus influenzae type b vaccine has led to the predominance of non-typable H. influenzae (NTHi). However, the occurrence of invasive NTHi infection based on gynecologic diseases is still rare.
Yoshito Nishimura +11 more
doaj +1 more source