Frontiers in Microbiology, 2023 BackgroundNeutrophilic asthma is poorly responsive to corticosteroids, and the mechanism underlying its pathogenesis remains unclear. Non-typeable Haemophilus influenzae (NTHi) is the most common bacterium found in induced sputum from patients with ...
Ying Zhang +4 more
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Opposing roles of PAK2 and PAK4 in synergistic induction of MUC5AC mucin by bacterium NTHi and EGF
Biochemical and Biophysical Research Communications, 2007 Hirofumi Kai, Huang Yuxian, Chen Yan
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Molecular surveillance of true nontypeable Haemophilus influenzae: an evaluation of PCR screening assays. [PDF]
PLoS ONE, 2012 BACKGROUND: Unambiguous identification of nontypeable Haemophilus influenzae (NTHi) is not possible by conventional microbiology. Molecular characterisation of phenotypically defined NTHi isolates suggests that up to 40% are Haemophilus haemolyticus (Hh);
Michael J Binks +8 more
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mSphere, 2020 Nontypeable Haemophilus influenzae (NTHI) colonizes the human nasopharynx, but when the host immune response is dysregulated by upper respiratory tract (URT) virus infection, NTHI can gain access to more distal airway sites and cause disease.
Elaine M. Mokrzan +3 more
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The role of NTHi colonization and infection in the pathogenesis of neutrophilic asthma
Respiratory Research, 2020 Asthma is a complex heterogeneous disease. The neutrophilic subtypes of asthma are described as persistent, more severe and corticosteroid-resistant, with higher hospitalization and mortality rates, which seriously affect the lives of asthmatic patients.
Jing Zhang +11 more
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The Role of Non-Typeable Haemophilus influenzae Biofilms in Chronic Obstructive Pulmonary Disease
Frontiers in Cellular and Infection Microbiology, 2021 Non-typeable Haemophilus influenzae (NTHi) is an ubiquitous commensal-turned-pathogen that colonises the respiratory mucosa in airways diseases including Chronic Obstructive Pulmonary Disease (COPD).
Jake R. Weeks +9 more
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Nocturnal Cerebral Oxygenation in Low-Altitude Residents With Pulmonary Vascular Disease Staying Overnight at High Altitude. Data From a Randomized, Controlled, Crossover Trial. [PDF]
Pulm CircABSTRACT Whether hypoxia during popular high‐altitude travel negatively affects cerebral oxygenation in vulnerable patients with pulmonary vascular disease (PVD) is unknown. We studied overnight cerebral tissue oxygen saturation (CTO) and desaturation index (cODI) in PVD‐patients at 2500 m and effects of supplemental oxygen therapy (SOT).
Kränzle C +15 more
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Intranasal immunization with nontypeable Haemophilus influenzae outer membrane vesicles induces cross-protective immunity in mice. [PDF]
PLoS ONE, 2012 Haemophilus influenzae is a Gram-negative human-restricted bacterium that can act as a commensal and a pathogen of the respiratory tract. Especially nontypeable H.
Sandro Roier +8 more
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, 2022 A: Functions of lactate dehydrogenases in NTHi strains. bd = bd-oxidase, TR = terminal reductase, MQ/MQH2 –menaquinone/menaquinol B: Model of carbon sources used by NTHi strains during infection of human epithelial cells.
Ama-Tawiah Essilfie (313146) +9 more
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Nontypeable Haemophilus influenzae invasion and persistence in the human respiratory tract
Frontiers in Cellular and Infection Microbiology, 2011 Nontypeable Haemophilus influenzae (NTHI) is an opportunistic bacterial pathogen of the human respiratory tract and is a leading cause of respiratory infections in children and adults.
Cara eClementi, Timothy eMurphy
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