Results 21 to 30 of about 4,073 (199)

Models of NTHi lactate dehydrogenase functions and NTHi carbon source utilization during tissue cell infection. [PDF]

open access: yes, 2022
A: Functions of lactate dehydrogenases in NTHi strains. bd = bd-oxidase, TR = terminal reductase, MQ/MQH2 –menaquinone/menaquinol B: Model of carbon sources used by NTHi strains during infection of human epithelial cells.
Ama-Tawiah Essilfie (313146)   +9 more
core   +1 more source

Adherence of Nontypeable Haemophilus influenzae to Cells and Substrates of the Airway Is Differentially Regulated by Individual ModA Phasevarions

open access: yesMicrobiology Spectrum, 2023
Adherence of nontypeable Haemophilus influenzae (NTHi) to the host airway is an essential initial step for asymptomatic colonization of the nasopharynx, as well as development of disease.
Preeti Garai   +5 more
doaj   +1 more source

NOD2/RICK-dependent β-defensin 2 regulation is protective for nontypeable Haemophilus influenzae-induced middle ear infection. [PDF]

open access: yesPLoS ONE, 2014
Middle ear infection, otitis media (OM), is clinically important due to the high incidence in children and its impact on the development of language and motor coordination.
Jeong-Im Woo   +5 more
doaj   +1 more source

Nontypeable Haemophilus influenzae Redox Recycling of Protein Thiols Promotes Resistance to Oxidative Killing and Bacterial Survival in Biofilms in a Smoke-Related Infection Model

open access: yesmSphere, 2022
Smoke exposure is a risk factor for community-acquired pneumonia, which is typically caused by host-adapted airway opportunists like nontypeable Haemophilus influenzae (NTHi).
Benjamin C. Hunt   +3 more
doaj   +1 more source

Aerosolization inhalation of non-typeable Haemophilus influenzae outer membrane vesicles contributing to neutrophilic asthma

open access: yesFrontiers in Microbiology, 2023
BackgroundNeutrophilic asthma is poorly responsive to corticosteroids, and the mechanism underlying its pathogenesis remains unclear. Non-typeable Haemophilus influenzae (NTHi) is the most common bacterium found in induced sputum from patients with ...
Ying Zhang   +4 more
doaj   +1 more source

A cascade model of dynamic cerebral autoregulation. [PDF]

open access: yesJ Physiol
Abstract figure legend This study examined a two‐component cascade model linking upstream dynamic cerebral autoregulation (dCA) with downstream microvascular function (MF) to explain how blood pressure oscillations influence cortical oxygenation. Transfer function analysis in the frequency domain was applied to quantify H1(f) (MAP→CBFV; dCA), H2(f ...
Kurazumi T   +8 more
europepmc   +2 more sources

Molecular surveillance of true nontypeable Haemophilus influenzae: an evaluation of PCR screening assays. [PDF]

open access: yesPLoS ONE, 2012
BACKGROUND: Unambiguous identification of nontypeable Haemophilus influenzae (NTHi) is not possible by conventional microbiology. Molecular characterisation of phenotypically defined NTHi isolates suggests that up to 40% are Haemophilus haemolyticus (Hh);
Michael J Binks   +8 more
doaj   +1 more source

Dexamethasone Inhibits Synergistic Induction of PDE4B Expression by Roflumilast and Bacterium NTHi [PDF]

open access: yesInternational Journal of Molecular Sciences, 2018
Phosphodiesterase 4B (PDE4B) plays an important role in inflammation. Recently we have reported that roflumilast as a PDE4-selective inhibitor, synergizes with nontypeable Haemophilus influenzae (NTHi) to up-regulate PDE4B expression in vitro and in vivo.
Byung-Cheol Lee   +3 more
openaire   +2 more sources

The Lung Immune Response to NontypeableHaemophilus influenzae(Lung Immunity to NTHi) [PDF]

open access: yesJournal of Immunology Research, 2015
Haemophilus influenzaeis divided into typeable or nontypeable strains based on the presence or absence of a polysaccharide capsule. The typeable strains (such as type b) are an important cause of systemic infection, whilst the nontypeable strains (designated as NTHi) are predominantly respiratory mucosal pathogens. NTHi is present as part of the normal
Paul T. King, Roleen Sharma
openaire   +4 more sources

Nontypeable Haemophilus influenzae Responds to Virus-Infected Cells with a Significant Increase in Type IV Pilus Expression

open access: yesmSphere, 2020
Nontypeable Haemophilus influenzae (NTHI) colonizes the human nasopharynx, but when the host immune response is dysregulated by upper respiratory tract (URT) virus infection, NTHI can gain access to more distal airway sites and cause disease.
Elaine M. Mokrzan   +3 more
doaj   +1 more source

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