Characterization of a nontypeable Haemophilus influenzae thermonuclease. [PDF]
PLoS ONE, 2018 Nontypeable Haemophilus influenzae (NTHi) has been shown to form biofilms, comprised of extracellular DNA (eDNA), in the middle ear and bronchus during clinical infections.
Christine Cho +5 more
doaj +1 more source
Tumor suppressor CYLD acts as a negative regulator for non-typeable Haemophilus influenza-induced inflammation in the middle ear and lung of mice. [PDF]
PLoS ONE, 2007 Non-typeable Haemophilus influenza (NTHi) is an important human pathogen causing respiratory tract infections in both adults and children. NTHi infections are characterized by inflammation, which is mainly mediated by nuclear transcription factor kappaB (
Jae Hyang Lim +9 more
doaj +1 more source
Correlation of NTHi-specific antibody binding with oxidative burst assay. [PDF]
, 2016 Spearman’s correlation of NTHi-specific (A) total IgG binding with IgG specific oxidative burst assay (OBA) and (B) total IgA binding with IgA specific OBA in serum with rho and p value presented.
Stephanie Leung (3368846) +11 more
core +1 more source
The roles of phosphocholine expressed on NTHi bacteria and host CRP in acute otitis media [PDF]
, 2023 Otitis Media (OM) is inflammation of the middle ear (ME). Non-typeable Haemophilus influenzae (NTHi) is one of the leading otopathogens causing OM. Phosphocholine (PCho) on the NTHi lipopolysaccharide influences host-pathogen interaction.
Bharj, Gurpreet
core +1 more source
Distribution of sequenced NTHi isolates. [PDF]
, 2015 Neighbor joining dendogram of NTHi strains used in this study. The tree is rooted with Eschericia coli MG1655 and is based on sequence comparisons of the concatenated adk, pgi, recA, infB and 16s rRNA gene sequences, with bootstrap values of greater than
Daniel J. Morton (296237) +3 more
core +1 more source
The role of TLR2 and bacterial lipoprotein in enhancing airway inflammation and immunity
Frontiers in Immunology, 2011 Non-typeable Haemophilus influenzae (NTHI) colonizes the lower respiratory tract of patients with chronic obstructive pulmonary disease (COPD) and also causes exacerbations of the disease.
Amit A Lugade +3 more
doaj +1 more source
Pediatric Investigation, 2023 Importance In remote communities of the Northern Territory, Australia, children experience high rates of otitis media (OM), commonly caused by non‐typeable Haemophilus influenzae (NTHi).
Sophia Bowman‐Derrick +12 more
doaj +1 more source
Developing an Intranasal Colonization Model for NTHi in Mice
The FASEB Journal, 2018 Nontypeable Haeomphilius influenzae (NTHi) is a Gram‐negative pathogenic bacterium that can live as a commensal in the nasopharynx or can be the cause of Acute Otitis Media (AOM). Although there are currently no approved vaccines in the US to protect against NTHi, several NTHi recombinant ...
Meghan O'Neil +7 more
openaire +1 more source
Inflammatory milieu is altered in NTHi+ve COPD BAL. [PDF]
, 2016 (A) GM-CSF (B) IL-6, (C) IL-8 and (D) IL-1β in BAL derived from two lung lobes were analysed by Luminex multiplex assay and the average concentration from both lobes is presented.
Stephanie Leung (3368846) +11 more
core +1 more source
Exploring microorganism-host interactions: Emerging organoid models and analytical approaches. [PDF]
mLifeAbstract Microorganisms play a vital role in human health through their interactions with the body. Studies of host–microbe mechanisms and interactions are crucial for advancing health management. Recently, the organoid‐based models have provided new platforms in this field.
Shi Y +6 more
europepmc +2 more sources