Developing a nontypeable Haemophilus influenzae (NTHi) vaccine
Vaccine, 2000 There is a current high demand for nontypable Haemophilus influenzae (NTHi) vaccines. Various options for the composition of such vaccines are possible.
Lauren Bakaletz +2 more
exaly +3 more sources
Pathogens, 2021 Nontypeable Haemophilus influenzae (NTHi) is a significant respiratory tract pathogen responsible for infections that collectively pose a substantial health and socioeconomic burden.
B. Atto, D. Kunde, D. Gell, S. Tristram
semanticscholar +3 more sources
NTHi induction of Cxcl2 and middle ear mucosal metaplasia in mice
Laryngoscope, 2013 Chronic otitis media (COM) develops after sustained inflammation and is characterized by secretory middle ear epithelial metaplasia and effusion, most frequently mucoid.
Diego Preciado
exaly +2 more sources
The Lung Immune Response to NontypeableHaemophilus influenzae(Lung Immunity to NTHi)
Journal of Immunology Research, 2015 Haemophilus influenzae is divided into typeable or nontypeable strains based on the presence or absence of a polysaccharide capsule. The typeable strains (such as type b) are an important cause of systemic infection, whilst the nontypeable strains ...
Paul King
exaly +2 more sources
Characterization of a conserved outer-membrane protein in non-typeable Haemophilus influenzae with an unidentified impact on phenotype [PDF]
Microbiology SpectrumNon-typeable Haemophilus influenzae (NTHi) is an opportunistic bacterial pathogen of the human airway and is a cause of significant morbidity and mortality worldwide.
Ashley J. Fraser +5 more
doaj +2 more sources
Pediatric Research, 2009 Nontypeable Haemophilus influenzae (NTHi) causes acute otitis media (AOM) in infants. Breast-feeding protects against AOM and/or nasopharyngeal (NP) colonization; however, the mechanism of protection is incompletely understood.
Timothy Murphy +2 more
exaly +2 more sources
Host-pathogen interaction profiling of nontypeable Haemophilus influenzae and Moraxella catarrhalis coinfection of bronchial epithelial cells [PDF]
mSphereChronic obstructive pulmonary disease (COPD) is a progressive inflammatory lung disease and the third leading cause of death globally. Nontypeable Haemophilus influenzae (NTHi) and Moraxella catarrhalis (Mcat) are common pathogens in individuals with ...
Adonis D’Mello +6 more
doaj +2 more sources
Multi-Component Vaccine Candidates Against Non-Typeable Haemophilus influenzae [PDF]
VaccinesBackground: Haemophilus influenzae (Hi), a Gram-negative bacterium, is divided into two broad categories: encapsulated and non-capsulated isolates, also called non-typeable Hi isolates (NTHi).
Nouria Belkacem +2 more
doaj +2 more sources
Exploiting haem-iron dependence of nontypeable Haemophilus influenzae: an avenue for future therapeutic development [PDF]
Frontiers in Cellular and Infection MicrobiologyNontypeable Haemophilus influenzae (NTHi) is a major respiratory pathogen that imposes a substantial disease burden, globally. Further amplifying the burden of NTHi-associated infections is the rapidly expanding spectrum and prevalence of antibiotic ...
Brianna Atto +4 more
doaj +2 more sources
Chorioamnionitis in the Second Trimester Secondary to Multidrug-Resistant <i>Haemophilus influenzae</i> Infection. [PDF]
Case Rep Infect DisPurpose Nontypeable Haemophilus influenzae (NTHi) is an emerging perinatal pathogen linked to chorioamnionitis, preterm birth, and early pregnancy loss. This case report describes the presentation, microbiologic findings, and management of second‐trimester NTHi‐associated chorioamnionitis, emphasizing diagnostic challenges and antimicrobial ...
Carlson KS, Korthals MB.
europepmc +2 more sources