Polarization increases nuclear stiffness in macrophages despite reduction in lamin A/C levels. [PDF]
Elpers MA +10 more
europepmc +1 more source
Integration of nuclear mechanosensing with integrin-extracellular matrix adhesions. [PDF]
Sandria S, King MC.
europepmc +1 more source
High-resolution nuclear cell biology by cryo-electron tomography. [PDF]
Kechagia Z, Medalia O.
europepmc +1 more source
Variable A-type lamin expression in Merkel cell carcinoma cell lines and its association with nuclear integrity. [PDF]
Stiekema M +6 more
europepmc +1 more source
B-type lamins maintain transcriptional homeostasis by spatially controlling chromatin-speckle proximity. [PDF]
Shin GS +12 more
europepmc +1 more source
A-type lamins anchor emerin at the inner nuclear membrane via two independent binding sites. [PDF]
Odell J, Nedza K, Lammerding J.
europepmc +1 more source
Nuclear dysfunction in aging and neurodegeneration. [PDF]
Aday A +7 more
europepmc +1 more source
The p.R249W Mutation in <i>LMNA</i>-Related Congenital Muscular Dystrophy Causes Nuclear Deformities and an Enrichment in Lamin A/C at the Ends of the Nucleus. [PDF]
Harvey C, Zhu Z, Han I, Cao K.
europepmc +1 more source
Nuclear Lamins: Their Structure, Assembly, and Interactions
Nuclear lamins are intermediate filament-type proteins that are the major building blocks of the nuclear lamina, a fibrous proteinaceous meshwork underlying the inner nuclear membrane. Lamins can also be localized in the nuclear interior, in a diffuse or spotted pattern.
Nico Stuurman, Ueli Aebi
exaly +5 more sources
Nuclear Lamins: Thin Filaments With Major Functions
The nuclear lamina is a nuclear peripheral meshwork that is mainly composed of nuclear lamins, although a small fraction of lamins also localizes throughout the nucleoplasm. Lamins are classified as type V intermediate filament (IF) proteins. Mutations in lamin genes cause at least 15 distinct human diseases, collectively termed laminopathies ...
Yosef Gruenbaum, Ohad Medalia
exaly +5 more sources

