Results 41 to 50 of about 709,714 (368)
Identification of a novel nuclear localization signal sequence in Chlamydia trachomatis-secreted hypothetical protein CT311. [PDF]
PLoS ONE, 2013 We previously reported that Chlamydia trachomatis hypothetical protein CT311 was secreted out of chlamydial inclusion and into host cell cytosol. We now found that CT311 further entered host cell nucleus at the late stage of infection and continued to ...
Lei Lei +3 more
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Nuclear Effectors in Plant Pathogenic Fungi
Mycobiology, 2022 The nuclear import of proteins is a fundamental process in the eukaryotes including plant. It has become evident that such basic process is exploited by nuclear effectors that contain nuclear localization signal (NLS) and are secreted into host cells by ...
Surajit De Mandal, Junhyun Jeon
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Analysis of conserved binding proteins for nuclear localization sequences [PDF]
Journal of Cell Science, 1993 ABSTRACT Correct targeting of nuclear proteins is mediated by nuclear localization sequences (NLS) which permit specific binding to the nucleus and subsequent translocation across the nuclear envelope via the nuclear pore complex. It is proposed that nuclear import is facilitated by NLS-receptors which reside in the cytoplasm and at the ...
M.A. Bossie +4 more
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Frontiers in Microbiology, 2021 Interferon exerts its antiviral activity by stimulating the expression of antiviral proteins. These interferon stimulate genes (ISGs) often target a group of viruses with unique molecular mechanisms.
Keli Chai +10 more
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Specific nuclear localizing sequence directs two myosin isoforms to the cell nucleus in calmodulin-sensitive manner. [PDF]
PLoS ONE, 2012 BACKGROUND: Nuclear myosin I (NM1) was the first molecular motor identified in the cell nucleus. Together with nuclear actin, they participate in crucial nuclear events such as transcription, chromatin movements, and chromatin remodeling.
Rastislav Dzijak +6 more
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Multiple Nuclear Localization Sequences Allow Modulation of 5‐Lipoxygenase Nuclear Import [PDF]
Traffic, 2004 The nuclear import of proteins typically requires the presence of a nuclear localization sequence (NLS). Some proteins have more than one NLS, but the significance of having multiple NLSs is unclear. The enzyme 5‐lipoxygenase (5‐LO) has three NLSs that, unlike the tight cluster of basic residues of the classical SV40 large T antigen NLS, contain ...
Luo, Ming +3 more
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Nuclear dynamics: Formation of bodies and trafficking in plant nuclei
Frontiers in Plant Science, 2022 The existence of the nucleus distinguishes prokaryotes and eukaryotes. Apart from containing most of the genetic material, the nucleus possesses several nuclear bodies composed of protein and RNA molecules.
Eduardo Muñoz-Díaz +3 more
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Stepwise synthesis of RNA conjugates carrying peptide sequences for RNA interference studies [PDF]
, 2009 Oligoribonucleotide conjugates carrying nuclear localization peptide sequences at the 3?-end were prepared stepwise on a single support. The siRNA duplex carrying the nuclear localization peptide sequence at the 3?-end of the passenger strand has similar
Aviñó, Anna +4 more
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Frontiers in Plant Science, 2014 Recent ultrastructural studies revealed that a structure similar to the vertebrate nuclear lamina exists in the nuclei of higher plants. However, plant genomes lack genes for lamins and intermediate-type filament proteins, and this suggests that plant ...
Yuta eKimura +3 more
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Human Gene Therapy, 1999 Polylysine (pLy) has been used successfully as a DNA carrier in receptor-mediated gene transfer, enhancement of transfection having been proposed to be in part through efficient nuclear targeting stemming from the resemblance of pLy to the nuclear localization sequence (NLS) from simian virus SV40 large tumor antigen (T-ag).
Chan, Chee Kai, Jans, David A
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