Results 41 to 50 of about 519,246 (298)

Phylogenetic analysis of the SAP30 family of transcriptional regulators reveals functional divergence in the domain that binds the nuclear matrix [PDF]

, 2009
Background: Deacetylation of histones plays a fundamental role in gene silencing, and this is mediated by a corepressor complex containing Sin3 as an essential scaffold protein. In this report we examine the evolution of two proteins in this complex, the
Heinonen, TYK, Lohi, O, Maki, M, Viiri, KM   +3 more
core   +3 more sources

Mutational analysis of the carbohydrate binding activity of the tobacco lectin [PDF]

, 2010
At present the three-dimensional structure of the tobacco lectin, further referred to as Nictaba, and its carbohydrate-binding site are unresolved. In this paper, we propose a three-dimensional model for the Nictaba domain based on the homology between ...
Barre, Annick, Lasanajak, Yi, Proost, Paul, Rouge, Pierre, Schouppe, Dieter, Smith, David F, Van Damme, Els   +6 more
core   +2 more sources

Effect of Nuclear Export Inhibitor Leptomycin B on the Intracellular Localization of HBV Core Protein into Hepatocytes Cell Line Huh-7 and HepG2 Cells

Indonesian Journal of Biotechnology, 2010
Leptomycin B (LMB) was originally discovered as a potent anti-fungal antibiotic from Streptomyces species. The cellular target of LMB has been identified as the nuclear export receptor CRM-1 or exportin-1, which is involved in nuclear trafficking of ...
Aris Haryanto, Nastiti Wijayanti, Michael Kann   +2 more
doaj   +1 more source

Identification of a classical bipartite nuclear localization signal in the Drosophila TEA/ATTS protein scalloped. [PDF]

PLoS ONE, 2011
Drosophila melanogaster wing development has been shown to rely on the activity of a complex of two proteins, Scalloped (Sd) and Vestigial (Vg). Within this complex, Sd is known to provide DNA binding though its TEA/ATTS domain, while Vg modulates this ...
Adam C Magico, John B Bell
doaj   +1 more source

Structural basis of nuclear import of flap endonuclease 1 (FEN1) [PDF]

, 2012
Flap endonuclease 1 (FEN1) is a member of the nuclease family and is structurally conserved from bacteriophages to humans. This protein is involved in multiple DNA-processing pathways, including Okazaki fragment maturation, stalled replication-fork ...
Agnes A. S. Takeda, Andrea C. de Barros, Bertinato, Boštjan Kobe, Catimel, Chelsky, Chen, Chiung-Wen Chang, Colledge, Conti, Cutress, Dingwall, Efthymiadis, Emsley, Fontes, Fontes, Fontes, Görlich, Hodel, Hosfield, Hu, Hwang, Hübner, Knudsen, Kobe, Koike, Koike, Kosugi, Kosugi, Laskowski, Lott, Marcos R. M. Fontes, Marfori, Mase, Miyamoto, Murshudov, Otwinowski, Qiu, Rexach, Sakurai, Studier, Takeda, Teh, Tsutakawa, Wallace, Yang, Zheng   +46 more
core   +2 more sources

Early initiation of a replication origin tethered at the nuclear periphery [PDF]

, 2010
Peer reviewedPublisher ...
Ansari, Brewer, Brickner, Bystricky, Cimbora, Cosgrove, Dimitrova, Donaldson, Ebrahimi, Ferguson, Friedman, Friedman, Friedman, Friedman, Goren, Hediger, Heun, Hiraga, Huberman, Iwase, Kitamura, Knott, Laroche, Li, McCarroll, Nieduszynski, Raghuraman, Shirahige, Straight, Taddei, Vogelauer, Yamashita, Zappulla   +32 more
core   +2 more sources

Deletion of the nuclear localization sequence and C-terminus of parathyroid hormone–related protein decreases osteogenesis and chondrogenesis but increases adipogenesis and myogenesis in murine bone marrow stromal cells

Journal of Tissue Engineering, 2015
The N-terminus of parathyroid hormone–related protein regulates bone marrow stromal cell differentiation. We hypothesized that the nuclear localization sequence and C-terminus are involved.
Blake E Hildreth, Krista M Hernon, Wessel P Dirksen, John Leong, Wachiraphan Supsavhad, Prosper N Boyaka, Thomas J Rosol, Ramiro E Toribio   +7 more
doaj   +1 more source

The Ctf18 RFC-like complex positions yeast telomeres but does not specify their replication time [PDF]

, 2006
Peer ...
Andrulis ED, Anne D Donaldson, Askree SH, Bermudez VP, Boulton SJ, Bowman GD, Bylund GO, Bystricky K, Cosgrove AJ, Dimitrova DS, Donaldson AD, E Douglas Robertson, Ferguson BM, Gartenberg MR, Gilbert DM, Gilbert N, Gotta M, Gottschling DE, Gravel S, Hanna JS, Hayashi A, Hediger F, Heun P, Heun P, Kenna MA, Kim J, Laroche T, Martin SG, Mayer ML, Merkle CJ, Naiki T, Ohta S, Palladino F, Petronczki M, Porter SE, Raghuraman MK, Raghuraman MK, Roy R, Shin-ichiro Hiraga, Skibbens RV, Smolikov S, Stellwagen AE, Stevenson JB, Strahl-Bolsinger S, Straight AF, Suter B, Taddei A, Taddei A, Tanabe H, Tanaka T, Tham WH, Woodfine K   +51 more
core   +2 more sources

Novel localization of formin mDia2: importin β-mediated delivery to and retention at the cytoplasmic side of the nuclear envelope

Biology Open, 2015
The formin family proteins are important regulators of actin polymerization that are involved in many cellular processes. However, little is known about their specific cellular localizations.
Xiaowei Shao, Keiko Kawauchi, G. V. Shivashankar, Alexander D. Bershadsky   +3 more
doaj   +1 more source

The Expression and Localization of N-Myc Downstream-Regulated Gene 1 in Human Trophoblasts [PDF]

, 2013
The protein N-Myc downstream-regulated gene 1 (NDRG1) is implicated in the regulation of cell proliferation, differentiation, and cellular stress response.
A Fotovati, A Karaczyn, B Chen, B Xu, Baosheng Chen, CR Roh, D Pflueger, D Piquemal, DM Byers, DM Nelson, E Alsat, E Shaw, EA Mostaghel, Eric Y. Chuang, EU Jung, HJ Kliman, J Hwang, Jacob C. Larkin, JF Mouillet, JR Hickok, K Hirata, K Kokame, K Ogata, KJ Livak, KT Kim, L Aravind, L Kalaydjieva, LW Donaldson, M Hunter, M Hunter, MA Zoroddu, N van Belzen, NT Le, O Genbacev, P Lachat, RB Donker, RH King, RK Riemer, RP Caruso, S Bandyopadhyay, S Chen, S Sibold, S Smith, S Stein, SJ Choi, SK Kachhap, SK Kurdistani, T Fujii, T Matsugaki, T Mishima, T Okuda, T Sugiki, TM Lin, V Melotte, VM Banz, W Ulrix, WT Schaiff, X Qu, X Xu, Xiao-Hua Shi, Y Sadovsky, Y Sadovsky, Y Song, Y Taketomi, Y Zhou, Yoel Sadovsky, Z Chen, Z Kovacevic   +67 more
core   +4 more sources