Results 81 to 90 of about 326,922 (335)

Nuclear pore complex-mediated modulation of TCR signaling is required for naïve CD4+ T cell homeostasis. [PDF]

, 2018
Nuclear pore complexes (NPCs) are channels connecting the nucleus with the cytoplasm. We report that loss of the tissue-specific NPC component Nup210 causes a severe deficit of naïve CD4+ T cells.
Borlido, Joana, Bradley, Linda M, Carrette, Florent, D'Angelo, Maximiliano A, Raices, Marcela, Sakuma, Stephen, Tinoco, Roberto   +6 more
core   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

FEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang, Naoki Sunagawa, Toma Kashima, Kiyohiko Igarashi, Akimasa Miyanaga, Shinya Fushinobu   +5 more
wiley   +1 more source

A role for Gle1, a regulator of DEAD-box RNA helicases, at centrosomes and basal bodies. [PDF]

, 2017
Control of organellar assembly and function is critical to eukaryotic homeostasis and survival. Gle1 is a highly conserved regulator of RNA-dependent DEAD-box ATPase proteins, with critical roles in both mRNA export and translation.
Akef, Abdalla, Jao, Li-En, Wente, Susan R   +2 more
core   +1 more source

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

FEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

Nuclear Pore-Like Structures in a Compartmentalized Bacterium.

PLoS ONE, 2017
Planctomycetes are distinguished from other Bacteria by compartmentalization of cells via internal membranes, interpretation of which has been subject to recent debate regarding potential relations to Gram-negative cell structure.
Evgeny Sagulenko, Amanda Nouwens, Richard I Webb, Kathryn Green, Benjamin Yee, Garry Morgan, Andrew Leis, Kuo-Chang Lee, Margaret K Butler, Nicholas Chia, Uyen Thi Phuong Pham, Stinus Lindgreen, Ryan Catchpole, Anthony M Poole, John A Fuerst   +14 more
doaj   +1 more source

Temporal Changes in Nuclear Envelope Permeability during Semi-Closed Mitosis in Dictyostelium Amoebae

Cells, 2023
The Amoebozoan Dictyostelium discoideum exhibits a semi-closed mitosis in which the nuclear membranes remain intact but become permeabilized to allow tubulin and spindle assembly factors to access the nuclear interior.
Kristina Mitic, Irene Meyer, Ralph Gräf, Marianne Grafe   +3 more
doaj   +1 more source

Multi-scale simulation of capillary pores and gel pores in Portland cement paste [PDF]

, 2015
The microstructures of Portland cement paste (water to cement ratio is 0.4, curing time is from 1 day to 28 days) are simulated based on the numerical cement hydration model, HUMOSTRUC3D (van Breugel, 1991; Koenders, 1997; Ye, 2003).
Gao, Peng, Wei, Jiangxiong, Ye, Guang, Yu, Qijun   +3 more
core  

Diffusion of Macromolecules across the Nuclear Pore Complex

, 2007
Nuclear pore complexes (NPCs) are very selective filters that monitor the transport between the cytoplasm and the nucleoplasm. Two models have been suggested for the plug of the NPC. They are (i) it is a reversible hydrogel or (ii) it is a polymer brush.
Alber, Alber, Ananya Debnath, Banik, Ben-Efraim, Bhattacharjee, Bickel, Cardarelli, Cardarelli, Chakrabarti, Chakrabarti, Chatterjee, Das, Doi, Elbaum, Fahrenkrog, Feldherr, Fiserova, Frey, Frey, Grünwald, Görlich, Herrman, Isgro, Isgro, Isgro, Justin Yamada, K.L. Sebastian, Kawakatsu, Keminer, Kim, Koutsioubas, Kowalczyk, Kraikvski, Kraikvski, Kubitscheck, Kustanovich, Landau, Leitenberger, Lim, Lim, Liu, Lowe, Ma, Ma, Maarel, Marcerou, Milner, Moussavi-Baygi, Moussavi-Baygi, Nielsen, Paine, Patel, Peters, Rajaraman, Rajarshi Chakrabarti, Reister, Ribbeck, Rout, Rout, Sebastian, Sebastian, Sebastian, Sprakel, Sprakel, Tabatabaei, Tran, Weise, Xu, Yang, Zilman, Zinn-Justin   +71 more
core   +1 more source

Spatially Resolved Monitoring of Drying of Hierarchical Porous Organic Networks [PDF]

, 2016
Evaporation kinetics of water confined in hierarchal polymeric porous media is studied by low field nuclear magnetic resonance (NMR). Systems synthesized with various degrees of cross-linker density render networks with similar pore sizes but different ...
Acosta, Rodolfo Hector, Gomez, Cesar Gerardo, Mattea, Carlos, Monti, Gustavo Alberto, Silletta, Emilia Victoria, Stapf, Siegfried, Strumia, Miriam Cristina, Velasco, Manuel Isaac   +7 more
core   +1 more source

The Nuclear Pore Complex and Nuclear Transport [PDF]

Cold Spring Harbor Perspectives in Biology, 2010
Internal membrane bound structures sequester all genetic material in eukaryotic cells. The most prominent of these structures is the nucleus, which is bounded by a double membrane termed the nuclear envelope (NE). Though this NE separates the nucleoplasm and genetic material within the nucleus from the surrounding cytoplasm, it is studded throughout ...
Susan R, Wente, Michael P, Rout
openaire   +2 more sources