Results 91 to 100 of about 623,335 (318)
PLoS BiologyNuclear export of mRNAs requires loading the mRNP to the transporter Mex67/Mtr2 in the nucleoplasm, controlled access to the pore by the basket-localised TREX-2 complex and mRNA release at the cytoplasmic site by the DEAD-box RNA helicase Dbp5 ...
Bernardo Papini Gabiatti +5 more
doaj +1 more source
Exotic mitotic mechanisms [PDF]
Open Biology, 2012 The emergence of eukaryotes around two billion years ago provided new challenges for the chromosome segregation machineries: the physical separation of multiple large and linear chromosomes from the microtubule-organizing centres by the nuclear envelope.
Hauke Drechsler, Andrew D. McAinsh
doaj +1 more source
Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation
FEBS Letters, EarlyView.Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley +1 more source
The Nuclear Pore Complex: A Target for NS3 Protease of Dengue and Zika Viruses
Viruses, 2020 During flavivirus infection, some viral proteins move to the nucleus and cellular components are relocated from the nucleus to the cytoplasm. Thus, the integrity of the main regulator of the nuclear-cytoplasmic transport, the nuclear pore complex (NPC ...
Luis Adrián De Jesús-González +11 more
doaj +1 more source
Effect of inhomogeneous surface relaxivity, pore geometry and internal field gradient on NMR logging:exact and perturbative theories and numerical investigations [PDF]
arXiv, 2009 Nuclear magnetic resonance is widely used as a probe of pore geometry and fluid composition in well logging. One of the critical assumptions often made is that the diffusion of fluid molecules is sufficiently fast to warrant the condition for direct mapping between the surface-enhanced relaxation rate and the pore geometry.
arxiv
Autophagy in cancer and protein conformational disorders
FEBS Letters, EarlyView.Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley +1 more source
Frontiers in Physiology, 2019 Cell fate is correlated to mechanotransduction, in which forces transmitted by the cytoskeleton filaments alter the nuclear shape, affecting transcription factor import/export, cells transcription activity and chromatin distribution.
F. Donnaloja +3 more
doaj +1 more source
Oxalate-Induced and Cell-Cycle-Dependent Expression of Nuclear Pore Complex Oxalate Binding Protein gp210 [PDF]
, 1999 The effect of oxalate, a constituent of renal stone, on the expression of nuclear pore complex oxalate binding protein (gp210) in Vero monkey kidney cells was examined.
Kannapiran, M, Selvam, R, Vijaya, R
core
FEBS Letters, EarlyView.The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang +2 more
wiley +1 more source
Flashlight Search Medial Axis: A Pixel-Free Pore-Network Extraction Algorithm [PDF]
arXiv, 2023 Pore-network models (PNMs) have become an important tool in the study of fluid flow in porous media over the last few decades, and the accuracy of their results highly depends on the extraction of pore networks. Traditional methods of pore-network extraction are based on pixels and require images with high quality.
arxiv