Results 41 to 50 of about 8,068,483 (291)

Structural and functional characterization of the p62 complex, a subcomplex of the nuclear pore complex [PDF]

, 2008
The nuclear pore complex (NPC) is a highly conserved eukaryotic protein complex, which perforates the nuclear envelope and regulates nucleocytoplasmic transport of cargos between the cytoplasm and nucleus.
Schwarz-Herion, Kyrill
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Assembly of nuclear pore complexes mediated by major vault protein [PDF]

Journal of Cell Science, 2009
During interphase growth of eukaryotic cells, nuclear pore complexes (NPCs) are continuously incorporated into the intact nuclear envelope (NE) by mechanisms that are largely unknown. De novo formation of NPCs involves local fusion events between the inner and outer nuclear membrane, formation of a transcisternal membranous channel of defined diameter ...
Friederike, Vollmar, Christian, Hacker, René-Peiman, Zahedi, Albert, Sickmann, Andrea, Ewald, Ulrich, Scheer, Marie-Christine, Dabauvalle   +6 more
openaire   +2 more sources

Dynamic insertion of membrane proteins at the endoplasmic reticulum [PDF]

, 2005
Most eukaryotic membrane proteins are cotranslationally integrated into the endoplasmic reticulum membrane by the Sec61 translocation complex. They are targeted to the translocon by hydrophobic signal sequences which induce the translocation of either ...
Higy, Marie
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Functional mammalian spliceosomal complex E contains SMN complex proteins in addition to U1 and U2 snRNPs [PDF]

, 2011
Copyright @ 2011 The Authors. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0), which permits unrestricted non-commercial use ...
E. M. Makarov (7607225), Evgeny M. Makarov, Andrew Bottrill, O. V. Makarova (7607222), Makarov, EM, Bottrill, A, N. Owen (7618997), Owen, N, Olga V. Makarova, Makarova, OV, A. Bottrill (7622258), Nicholas Owen   +11 more
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Internal iamin structures within G1 nuclei of human dermal fibroblasts [PDF]

, 1993
The nuclear lamina is a mesh-like network of fibres subjacent to the inner nuclear membrane that is believed to be involved in the specific spatial reorganisation of chromatin after mitosis.
Kill, IR, Hutchison, CJ, O’Farrell, M, Bridger, JM   +3 more
core   +6 more sources

The NAE Pathway: Autobahn to the Nucleus for Cell Surface Receptors

Cells, 2019
Various growth factors and full-length cell surface receptors such as EGFR are translocated from the cell surface to the nucleoplasm, baffling cell biologists to the mechanisms and functions of this process. Elevated levels of nuclear EGFR correlate with
Poonam Shah, Alexandre Chaumet, Stephen J. Royle, Frederic A. Bard   +3 more
doaj   +1 more source

NUP-1 is a large coiled-coil nucleoskeletal protein in Trypanosomes with lamin-like functions [PDF]

, 2012
A unifying feature of eukaryotic nuclear organization is genome segregation into transcriptionally active euchromatin and transcriptionally repressed heterochromatin.
Wan, Yakun, Kelly N DuBois, J. David Barry, Rout, Michael P., Alsford, S., Holden, Jennifer M., DuBois, K.N., Rout Michael P., Rout, Michael P, Jean-Mathieu Bart (176093), Field, Mark C, DuBois, Kelly N., Alsford Sam, Aitchison, J.D., Buisson, J., Mathieu Bart, Barry, J. David, Navarro Miguel, Horn David, Field, Mark C., Field Mark C., Misteli, T., Ratushny, Alexander V., Swiderski, Michal, Horn, David, Rout, M.P., Mark C. Field (129657), David Horn (24969), Jennifer M. Holden, Bastin Philippe, DuBois, Kelly N, Alexander V. Ratushny (102304), Barry, J.D., Barry, J David, Holden Jennifer M., Miguel Navarro, Michal Swiderski (176090), John D. Aitchison (102330), Bart, J., Johanna Buisson, J David Barry, John D. Aitchison, Holden, Jennifer M, Bastin, Philippe, DuBois Kelly N., Navarro, M., Barry J. David, Philippe Bastin (25974), Michael P. Rout (25373), Aitchison John D., Jennifer M Holden, Ratushny, A.V., Kelly N. Dubois, Buisson Johanna, Field, M.C., Alsford, Sam, Philippe Bastin, Swiderski, M., Wan, Y., Ratushny, Alexander V, Bastin, P., Kelly N. DuBois (176072), Horn, D., Michael P Rout, Aitchison, John D, Jean-Mathieu Bart, Buisson, Johanna, Bart, Jean-Mathieu, Sam Alsford (24967), Yakun Wan, David Horn, Mark C. Field, J. David Barry (60385), Navarro, Miguel, Aitchison, John D., Jennifer M. Holden (176080), Miguel Navarro (176103), Sam Alsford, Bart Jean-Mathieu, Ratushny Alexander V., Michael P. Rout, Yakun Wan (176097), Wan Yakun, Horn, David; id_orcid, Holden, J.M., Swiderski Michal, John D Aitchison, Mark C Field, Johanna Buisson (176084), Michal Swiderski, Er V. Ratushny, Alexander V Ratushny   +91 more
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The HSV1 Tail-Anchored Membrane Protein pUL34 Contains a Basic Motif That Supports Active Transport to the Inner Nuclear Membrane Prior to Formation of the Nuclear Egress Complex

Viruses, 2021
Herpes simplex virus type 1 nucleocapsids are released from the host nucleus by a budding process through the nuclear envelope called nuclear egress. Two viral proteins, the integral membrane proteins pUL34 and pUL31, form the nuclear egress complex at ...
Christina Funk, Débora Marques da Silveira e Santos, Melanie Ott, Verena Raschbichler, Susanne M. Bailer   +4 more
doaj   +1 more source

The nuclear pore complex protein ALADIN is mislocalized in triple A syndrome [PDF]

Proceedings of the National Academy of Sciences, 2003
Triple A syndrome is a human autosomal recessive disorder characterized by an unusual array of tissue-specific defects. Triple A syndrome arises from mutations in a WD-repeat protein of unknown function called ALADIN (also termed Adracalin or AAAS).
Janet M, Cronshaw, Michael J, Matunis
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Reduction of dimensionality in Karyopherinβ1 mediated transport on FG domains [PDF]

, 2014
Many molecular transport processes in living cells proceed by facilitated diffusion in two dimensions instead of three, but how this process works remains poorly understood.
Schleicher, Kai D.
core   +1 more source