Results 21 to 30 of about 8,068,483 (291)

Differential Mitotic Phosphorylation of Proteins of the Nuclear Pore Complex [PDF]

Journal of Biological Chemistry, 1995
During each cell cycle, the nucleus of higher eukaryotes undergoes a dramatic assembly and disassembly. These events can be faithfully reproduced in vitro using cell-free extracts derived from Xenopus eggs. Such extracts contain three major N-acetylglucosaminylated proteins, p200, p97, and p60.
C, Macaulay, E, Meier, D J, Forbes
openaire   +2 more sources

An Endoribonuclease Functionally Linked to Perinuclear mRNP Quality Control Associates with the Nuclear Pore Complexes [PDF]

, 2009
Nuclear mRNA export is a crucial step in eukaryotic gene expression, which is in yeast coupled to cotranscriptional messenger ribonucleoprotein particle ( mRNP) assembly and surveillance.
Attila Rácz, Skružný Michal, Julan Weng, Racz, Attila, Ed Hurt, Rácz Attila, Weng Julan, David Tollervey, Schneider, Claudia, Hurt, Ed, Skruzny, Michal, Hurt Ed, Claudia Schneider, Schneider Claudia, Weng, Julan, Tollervey, David, Michal Skruzný, Tollervey David   +17 more
core   +1 more source

Detecting Selective Protein Binding Inside Plasmonic Nanopores: Toward a Mimic of the Nuclear Pore Complex

Frontiers in Chemistry, 2018
Biosensors based on plasmonic nanostructures offer label-free and real-time monitoring of biomolecular interactions. However, so do many other surface sensitive techniques with equal or better resolution in terms of surface coverage.
Bita Malekian, Rafael L. Schoch, Timothy Robson, Gustav Ferrand -Drake del Castillo, Kunli Xiong, Gustav Emilsson, Larisa E. Kapinos, Roderick Y. H. Lim, Andreas Dahlin   +8 more
doaj   +1 more source

Cohesiveness tunes assembly and morphology of FG nucleoporin domain meshworks – Implications for nuclear pore permeability [PDF]

, 2013
Nuclear pore complexes control the exchange of macromolecules between the cytoplasm and the nucleus. A selective permeability barrier that arises from a supramolecular assembly of intrinsically unfolded nucleoporin domains rich in phenylalanine-glycine ...
Frey, S., Labokha, Aksana A., Eisele, Nico B., Frey, Steffen, Görlich, D., Richter, Ralf P., Eisele, N., Richter, R., Steffen Frey, Dirk Görlich, Richter , R., Labokha, A., Ralf P. Richter, Aksana A. Labokha, Görlich, Dirk, Nico B. Eisele, Goerlich, D.   +16 more
core   +1 more source

Protein Transport by the Nuclear Pore Complex: Simple Biophysics of a Complex Biomachine [PDF]

Biophysical Journal, 2017
In eukaryotic cells, transport of molecules between the nucleus and the cytoplasm is facilitated by highly selective and efficient biomachines known as nuclear pore complexes (NPCs). The structural details of NPCs vary across species, with many of their constituent proteins exhibiting relatively low sequence conservation; yet the NPC as a whole retains
Tijana, Jovanovic-Talisman, Anton, Zilman   +1 more
openaire   +2 more sources

NDC1 : a crucial membrane-integral nucleoporin of metazoan nuclear pore complexes [PDF]

, 2006
POM121 and gp210 were, until this point, the only known membrane-integral nucleoporins (Nups) of vertebrates and, thus, the only candidate anchors for nuclear pore complexes (NPCs) within the nuclear membrane. In an accompanying study (Stavru et al.), we
Gorlich, D., Hülsmann, Bastian, Anne Spang, Cordes, V., Stavru, F., Hartmann, E., Dirk Görlich, Spang, Anne, Cordes, Volker, C., Volker C. Cordes, Hülsmann, B., Hulsmann, B. B., Bastian B. Hülsmann, Cordes, V. C., Hartmann, Enno, Fabrizia Stavru, Görlich, Dirk, Stavru, Fabrizia, Enno Hartmann, Spang, A., Cordes, Volker,   +20 more
core   +1 more source

splitSMLM, a spectral demixing method for high-precision multi-color localization microscopy applied to nuclear pore complexes

Communications Biology, 2022
The development of an image splitter based multi-colour single-molecule localization microscopy method (splitSMLM) in combination with a spectral demixing algorithm improves localization accuracy as exemplified by three-colour imaging of nuclear pore ...
Leonid Andronov, Rachel Genthial, Didier Hentsch, Bruno P. Klaholz   +3 more
doaj   +1 more source

The nuclear pore complex : its role in chromatin structure and RNA export [PDF]

, 2015
Epigenetic regulation of gene expression is a relatively new and rapidly developing research field. It studies the mechanisms of regulation of gene expression, which although heritable, occur independently of changes in the DNA sequence and certainly aid
Hristova, Emilia
core   +1 more source

NucEnvDB: A Database of Nuclear Envelope Proteins and Their Interactions

Membranes, 2023
The nuclear envelope (NE) is a double-membrane system surrounding the nucleus of eukaryotic cells. A large number of proteins are localized in the NE, performing a wide variety of functions, from the bidirectional exchange of molecules between the ...
Fotis A. Baltoumas, Dimitrios Sofras, Avgi E. Apostolakou, Zoi I. Litou, Vassiliki A. Iconomidou   +4 more
doaj   +1 more source

Kap-Centric control of nuclear pores based on promiscuous binding to FG nucleoporins [PDF]

, 2014
Nuclear pore complexes (NPCs) are remarkable molecular machines that perforate the nuclear envelope (NE) in eukaryotic cells and mediate the rapid bidirectional traffic of hundreds of proteins, ribonucleoproteins, and metabolites across the nuclear ...
Wagner, Raphael S.
core   +1 more source