Nuclear pore complex proteins are involved in centromere distribution [PDF]
iScienceSummary: The subnuclear distribution of centromeres is cooperatively regulated by condensin II and the linker of nucleoskeleton and cytoskeleton (LINC) complex.
Nanami Ito +6 more
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Partial Disassembly of the Nuclear Pore Complex Proteins during Semi-Closed Mitosis in Dictyostelium discoideum [PDF]
Cells, 2022 Dictyostelium cells undergo a semi-closed mitosis, during which the nuclear envelope (NE) persists; however, free diffusion between the cytoplasm and the nucleus takes place.
Kristina Mitic +3 more
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Direct Visualization of Single Nuclear Pore Complex Proteins Using Genetically-Encoded Probes for DNA-PAINT [PDF]
Angew Chem Int Ed Engl, 2019 The nuclear pore complex (NPC) is one of the largest and most complex protein assemblies in the cell and, among other functions, serves as the gatekeeper of nucleocytoplasmic transport.
Auer, A. +10 more
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The NAE Pathway: Autobahn to the Nucleus for Cell Surface Receptors [PDF]
Cells, 2019 Various growth factors and full-length cell surface receptors such as EGFR are translocated from the cell surface to the nucleoplasm, baffling cell biologists to the mechanisms and functions of this process. Elevated levels of nuclear EGFR correlate with
Poonam Shah +3 more
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Higher nucleoporin-Importinβ affinity at the nuclear basket increases nucleocytoplasmic import. [PDF]
PLoS ONE, 2013 Several in vitro studies have shown the presence of an affinity gradient in nuclear pore complex proteins for the import receptor Importinβ, at least partially contributing to nucleocytoplasmic transport, while others have historically argued against the
Mohammad Azimi, Mohammad R K Mofrad
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DNA origami scaffold for studying intrinsically disordered proteins of the nuclear pore complex [PDF]
Nature Communications, 2018 FG-Nups are disordered proteins in the nuclear pore complex (NPC) where they selectively control nuclear transport. Here authors build NPC-mimics based on DNA origami rings which attach a certain numbers of Nups to analyse those nanopores by cryoEM and ...
Philip Ketterer +9 more
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A new family of yeast nuclear pore complex proteins. [PDF]
The Journal of cell biology, 1992 We have identified a novel family of yeast nuclear pore complex proteins. Three individual members of this family, NUP49, NUP100, and NUP116, have been isolated and then characterized by a combination of molecular genetics and immunolocalization. Employing immunoelectron and immunofluorescence microscopy on yeast cells, we found that the binding of a ...
Susan R. Wente +2 more
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Detecting Selective Protein Binding Inside Plasmonic Nanopores: Toward a Mimic of the Nuclear Pore Complex [PDF]
Frontiers in Chemistry, 2018 Biosensors based on plasmonic nanostructures offer label-free and real-time monitoring of biomolecular interactions. However, so do many other surface sensitive techniques with equal or better resolution in terms of surface coverage.
Bita Malekian +8 more
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Journal of VirologyUnrelated pathogens, including viruses and bacteria, use a common short linear motif (SLiM) to interact with cellular kinases of the RSK (p90 S6 ribosomal kinase) family.
Belén Lizcano-Perret +6 more
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eLife, 2018 Nuclear pore complexes (NPCs) lined with intrinsically disordered FG-domains act as selective gatekeepers for molecular transport between the nucleus and the cytoplasm in eukaryotic cells.
Adithya N Ananth +8 more
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