Results 1 to 10 of about 97,972 (258)
Nuclear pore complex proteins are involved in centromere distribution [PDF]
iScienceSummary: The subnuclear distribution of centromeres is cooperatively regulated by condensin II and the linker of nucleoskeleton and cytoskeleton (LINC) complex.
Nanami Ito +6 more
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Partial Disassembly of the Nuclear Pore Complex Proteins during Semi-Closed Mitosis in Dictyostelium discoideum [PDF]
Cells, 2022 Dictyostelium cells undergo a semi-closed mitosis, during which the nuclear envelope (NE) persists; however, free diffusion between the cytoplasm and the nucleus takes place.
Kristina Mitic +3 more
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Dynamics and diverse functions of nuclear pore complex proteins. [PDF]
Nucleus, 2012 Nuclear pore complexes (NPCs) are best known for their central role in controlling the molecular trafficking between the cytoplasm and the nucleus. NPCs are assembled from about 30 different proteins and a growing body of evidence suggests that these nucleoporins are not only acting in the context of NPCs, but also in the nucleoplasm and cytoplasm.
Chatel G, Fahrenkrog B.
europepmc +5 more sources
Direct Visualization of Single Nuclear Pore Complex Proteins Using Genetically-Encoded Probes for DNA-PAINT. [PDF]
Angew Chem Int Ed Engl, 2019 Schlichthaerle T +10 more
europepmc +2 more sources
Acta Neuropathologica Communications, 2021 Nuclear pore complex injury has recently emerged as an early and significant contributor to familial and sporadic ALS disease pathogenesis. However, the molecular events leading to this pathological phenomenon characterized by the reduction of specific ...
Alyssa N. Coyne, Jeffrey D. Rothstein
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Nucleocytoplasmic Trafficking Perturbation Induced by Picornaviruses
Viruses, 2021 Picornaviruses are positive-stranded RNA viruses. Even though replication and translation of their genome take place in the cytoplasm, these viruses evolved different strategies to disturb nucleocytoplasmic trafficking of host proteins and RNA. The major
Belén Lizcano-Perret, Thomas Michiels
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Nature Communications, 2021 The involvement of nuclear pore proteins in cellular mechanosensing and metastasis is unclear. Here the authors identify that nuclear pore protein NUP210 promotes metastasis through the interaction with mechanotransducer LINC complex protein and ...
Ruhul Amin +17 more
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Nuclear Pore Complex Proteins in Alzheimer Disease [PDF]
Journal of Neuropathology and Experimental Neurology, 2006 Ultrastructural studies of neurofibrillary tangles in Alzheimer disease (AD) have demonstrated a close relationship between nuclear pores and the cytoplasmic paired helical filaments comprising the tangles, as well as nuclear irregularity in many tangle-bearing neurons; nuclear pore aggregation has been observed in nearby neurons.
Lynette G, Sheffield +3 more
openaire +2 more sources
The Nuclear Pore Complex Is a Key Target of Viral Proteases to Promote Viral Replication
Viruses, 2021 Various viruses alter nuclear pore complex (NPC) integrity to access the nuclear content favoring their replication. Alteration of the nuclear pore complex has been observed not only in viruses that replicate in the nucleus but also in viruses with a ...
Luis Adrián De Jesús-González +7 more
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A complex of nuclear pore proteins required for pore function. [PDF]
The Journal of cell biology, 1991 A family of proteins bearing novel N-acetylglucosamine residues has previously been found to be required to form functional nuclear pores. To begin to determine which of the proteins in this family are essential for pore function, antisera were raised to each of three members of the family, p62, p58, and p54.
D R, Finlay +4 more
openaire +2 more sources