Results 11 to 20 of about 1,042,939 (323)
Nuclear Transport of Yeast Proteasomes [PDF]
Biomolecules, 2014 Proteasomes are conserved protease complexes enriched in the nuclei of dividing yeast cells, a major site for protein degradation. If yeast cells do not proliferate and transit to quiescence, metabolic changes result in the dissociation of proteasomes ...
Cordula Enenkel
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Classical Nuclear Motion in Quantum Transport [PDF]
Physical Review Letters, 2006 An ab initio quantum-classical mixed scheme for the time evolution of electrode-device-electrode systems is introduced to study nuclear dynamics in quantum transport. Two model systems are discussed to illustrate the method. Our results provide the first
Carl-Olof Almbladh +4 more
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Nuclear transport: what a kary-on! [PDF]
Structure, 1999 Compartmentalisation in eukaryotic cells presents special problems in macromolecular transport. Here we use the recently determined X-ray structures of a number of components of the nuclear transport machinery as a framework to review current understanding of this fundamental biological process.
S.J. Gamblin, Stephen J. Smerdon
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Cell, 2002 Nuclear Transport Edited by Karsten Weiss New York: Springer Verlag (2001). $104.75Nucleocytoplasmic transport plays a pivotal role in eukaryotic cell function and is relevant to many areas of cell biology. As such, it is somewhat surprising that books on this subject are in short supply. Nuclear Transport, edited by Karsten Weis, is a welcome addition.
Amnon Harel, Douglass J. Forbes
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Non-transport roles of nuclear import receptors: In need of the right balance
Frontiers in Cell and Developmental Biology, 2022 Nuclear import receptors ensure the recognition and transport of proteins across the nuclear envelope into the nucleus. In addition, as diverse processes as mitosis, post-translational modifications at mitotic exit, ciliogenesis, and phase separation ...
Michela Damizia +4 more
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The Nuclear Transport Protein Importin-5: A Promising Target in Oncology and Virology
CHIMIA, 2021 Cellular homeostasis importantly relies on the correct nucleoplasmic distribution of a large number of RNA molecules and proteins, which are shuttled by specialized transport receptors.
Rémi Patouret
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Herpes simplex virus ICP27 protein directly interacts with the nuclear pore complex through NUP62, inhibiting host nucleocytoplasmic transport pathways [PDF]
, 2012 The herpes simplex virus ICP27 protein is important for the expression and nuclear export of viral mRNAs. Although several binding sites have been mapped along the ICP27 sequence for various RNA and protein partners including the transport receptor TAP ...
Arnold +83 more
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The Nuclear Pore Complex and Nuclear Transport [PDF]
Cold Spring Harbor Perspectives in Biology, 2010 Internal membrane bound structures sequester all genetic material in eukaryotic cells. The most prominent of these structures is the nucleus, which is bounded by a double membrane termed the nuclear envelope (NE). Though this NE separates the nucleoplasm and genetic material within the nucleus from the surrounding cytoplasm, it is studded throughout ...
Susan R. Wente, Michael P. Rout
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Structural determinants of nuclear export signal orientation in binding to exportin CRM1
eLife, 2015 The Chromosome Region of Maintenance 1 (CRM1) protein mediates nuclear export of hundreds of proteins through recognition of their nuclear export signals (NESs), which are highly variable in sequence and structure.
Ho Yee Joyce Fung +3 more
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Nuclear Transporter IPO13 Is Central to Efficient Neuronal Differentiation
Cells, 2022 Molecular transport between the nucleus and cytoplasm of the cell is mediated by the importin superfamily of transport receptors, of which the bidirectional transporter Importin 13 (IPO13) is a unique member, with a critical role in early embryonic ...
Katarzyna A. Gajewska +2 more
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