Results 31 to 40 of about 3,896,158 (300)
G3: Genes, Genomes, Genetics, 2016 Protein transport between the nucleus and cytoplasm of eukaryotic cells is tightly regulated, providing a mechanism for controlling intracellular localization of proteins, and regulating gene expression. In this study, we have investigated the importance
Kenneth D. Belanger +4 more
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Molecular determinants of large cargo transport into the nucleus
eLife, 2020 Nucleocytoplasmic transport is tightly regulated by the nuclear pore complex (NPC). Among the thousands of molecules that cross the NPC, even very large (>15 nm) cargoes such as pathogens, mRNAs and pre-ribosomes can pass the NPC intact.
Giulia Paci +4 more
doaj +1 more source
Signaling to Nuclear Transport [PDF]
Developmental Cell, 2008 In a recent issue of Molecular Cell, Yoon et al. provide evidence for the control of nucleocytoplasmic transport by protein kinase signaling pathways through phosphorylation of RanBP3, an accessory factor in the Ran GTPase system. This mechanism may coordinate nucleocytoplasmic transport with other mitogenic effects of these pathways.
openaire +5 more sources
Cohesiveness tunes assembly and morphology of FG nucleoporin domain meshworks – Implications for nuclear pore permeability [PDF]
, 2013 Nuclear pore complexes control the exchange of macromolecules between the cytoplasm and the nucleus. A selective permeability barrier that arises from a supramolecular assembly of intrinsically unfolded nucleoporin domains rich in phenylalanine-glycine ...
Frey, S. +16 more
core +1 more source
Consequence prediction in nuclear transport explosion accident using long short-term memory network
Fushe yanjiu yu fushe gongyi xuebao, 2023 During the transportation of components related to nuclear materials, accidental chemical explosions may occur, resulting in the release of radionuclides.
RUAN Lingpan +5 more
doaj +1 more source
Kap-Centric control of nuclear pores based on promiscuous binding to FG nucleoporins [PDF]
, 2014 Nuclear pore complexes (NPCs) are remarkable molecular machines that perforate the nuclear envelope (NE) in eukaryotic cells and mediate the rapid bidirectional traffic of hundreds of proteins, ribonucleoproteins, and metabolites across the nuclear ...
Wagner, Raphael S.
core +1 more source
Transport outlook 2009: Globalisation, crisis and transport [PDF]
, 2009 This second ITF Transport Outlook continues building towards a full-fledged Transport Outlook, building upon the first Outlook (JTRC, 20081). The 2008 Outlook investigated the relation between expected GDP evolution and the demand for road transport ...
International Transport Forum, OECD
core +1 more source
Meeting society's transport needs under tight budgets [PDF]
, 2011 In the aftermath of the 2008 financial crisis, both the private and public sectors face stringent constraints in funding for transport infrastructure investment and transport services.
International Transport Forum, OECD
core +1 more source
The Tau of Nuclear-Cytoplasmic Transport [PDF]
Neuron, 2018 Aggregation of microtubule-associated protein tau is the hallmark of tauopathies, including Alzheimer's disease. Eftekharzadeh et al. (2018) demonstrate that pathogenic tau alters nucleocytoplasmic transport by interacting with components of the nuclear pore complex, revealing a perturbation shared by multiple neurodegenerative diseases.
Evan, Lester, Roy, Parker
openaire +2 more sources
Reduction of dimensionality in Karyopherinβ1 mediated transport on FG domains [PDF]
, 2014 Many molecular transport processes in living cells proceed by facilitated diffusion in two dimensions instead of three, but how this process works remains poorly understood.
Schleicher, Kai D.
core +1 more source