Results 21 to 30 of about 420,473 (212)
Consequence prediction in nuclear transport explosion accident using long short-term memory network
Fushe yanjiu yu fushe gongyi xuebao, 2023 During the transportation of components related to nuclear materials, accidental chemical explosions may occur, resulting in the release of radionuclides.
RUAN Lingpan +5 more
doaj +1 more source
Active Nuclear Import of Membrane Proteins Revisited
Cells, 2015 It is poorly understood how membrane proteins destined for the inner nuclear membrane pass the crowded environment of the Nuclear Pore Complex (NPC). For the Saccharomyces cerevisiae proteins Src1/Heh1 and Heh2, a transport mechanism was proposed where ...
Justyna K. Laba +5 more
doaj +1 more source
Frontiers in Immunology, 2023 The Th17+ arrangement is critical for orchestrating both innate and acquired immune responses. In this context, the serum and glucocorticoid regulated kinase 1 (SGK1) exerts a key role in the governance of IL-23R-dependent Th17+ maturation, through the ...
Carolina Brescia +19 more
doaj +1 more source
Viral Appropriation: Laying Claim to Host Nuclear Transport Machinery
Cells, 2019 Protein nuclear transport is an integral process to many cellular pathways and often plays a critical role during viral infection. To overcome the barrier presented by the nuclear membrane and gain access to the nucleus, virally encoded proteins have ...
Tanner M. Tessier +3 more
doaj +1 more source
Structural determinants of nuclear export signal orientation in binding to exportin CRM1
eLife, 2015 The Chromosome Region of Maintenance 1 (CRM1) protein mediates nuclear export of hundreds of proteins through recognition of their nuclear export signals (NESs), which are highly variable in sequence and structure.
Ho Yee Joyce Fung +3 more
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Nuclear Import of Hepatitis B Virus Capsids and Genome
Viruses, 2017 Hepatitis B virus (HBV) is an enveloped pararetrovirus with a DNA genome, which is found in an up to 36 nm-measuring capsid. Replication of the genome occurs via an RNA intermediate, which is synthesized in the nucleus.
Lara Gallucci, Michael Kann
doaj +1 more source
Arabidopsis FHY1 and FHY1-LIKE Are Not Required for Phytochrome A Signal Transduction in the Nucleus
Plant Communications, 2020 Photoreceptors of the phytochrome family control a multitude of responses in plants. Phytochrome A (phyA) is essential for far-red light perception, which is important for germination and seedling establishment in strong canopy shade.
Chiara Menon +2 more
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Variation in the nuclear effects of infection by different human rhinovirus serotypes.
Frontiers in Microbiology, 2015 Human rhinovirus (HRV) is a positive sense RNA virus, which, despite replicating in the cytoplasm, has a significant impact on nuclear transport and nuclear localisation of host proteins.
Erin Joanne Walker +3 more
doaj +1 more source
Differential Behaviours and Preferential Bindings of Influenza Nucleoproteins on Importins-α
Viruses, 2020 Influenza viruses are negative single-stranded RNA viruses with nuclear transcription and replication. They enter the nucleus by using the cellular importin-α/-β nuclear import machinery.
Amélie Donchet +4 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Primary cutaneous anaplastic large cell lymphoma (pcALCL) is a rare pediatric CD30‐positive T‐cell lymphoproliferative disorder with an excellent prognosis, but its genomic drivers are poorly defined. We report three children with skin‐limited disease demonstrating striking molecular heterogeneity, including NPM::ALK, NUP214::FRK, and a novel ...
Shoshana Greenberger +7 more
wiley +1 more source