Results 21 to 30 of about 1,042,939 (323)

Nuclear geometry effect and transport coefficient in semi-inclusive lepton-production of hadrons off nuclei [PDF]

, 2015
Hadron production in semi-inclusive deep-inelastic scattering of leptons from nuclei is an ideal tool to determine and constrain the transport coefficient in cold nuclear matter. The leading-order computations for hadron multiplicity ratios are performed
Duan, Chun-Gui, Liu, Na, Miao, Wen-Dan, Song, Li-Hua   +3 more
core   +3 more sources

The Ebola Virus Interferon Antagonist VP24 Undergoes Active Nucleocytoplasmic Trafficking

Viruses, 2021
Viral interferon (IFN) antagonist proteins mediate evasion of IFN-mediated innate immunity and are often multifunctional, with distinct roles in viral replication.
Angela R. Harrison, Cassandra T. David, Stephen M. Rawlinson, Gregory W. Moseley   +3 more
doaj   +1 more source

Signaling to Nuclear Transport [PDF]

Developmental Cell, 2008
In a recent issue of Molecular Cell, Yoon et al. provide evidence for the control of nucleocytoplasmic transport by protein kinase signaling pathways through phosphorylation of RanBP3, an accessory factor in the Ran GTPase system. This mechanism may coordinate nucleocytoplasmic transport with other mitogenic effects of these pathways.
openaire   +4 more sources

Higher nucleoporin-Importinβ affinity at the nuclear basket increases nucleocytoplasmic import. [PDF]

, 2013
Several in vitro studies have shown the presence of an affinity gradient in nuclear pore complex proteins for the import receptor Importinβ, at least partially contributing to nucleocytoplasmic transport, while others have historically argued against the
Azimi, Mohammad, Mofrad, Mohammad
core   +2 more sources

SnapShot: Nuclear Transport

Cell, 2007
I Kap95 Kap60 adaptor for cNLS proteins Yes Importin-b1 Importin-a adaptor for cNLS proteins, Snurportin adaptor for U snRNPsII Kap95 — Yes Importin-b1 SREBP-2, HIV Rev and TAT, Cyclin BKap104 Nab2, Hrp1 (mRNA-binding proteins)t.s. Transportin or Transportin 2PY-NLS-containing proteins, mRNA-binding proteins, histones, ribosomal proteinsKap123 SRP ...
Susan R. Wente, Elizabeth J. Tran, Timothy A. Bolger   +2 more
openaire   +2 more sources

A system-wide mislocalization of RNA-binding proteins in motor neurons is a new feature of ALS

Neurobiology of Disease, 2021
Amyotrophic lateral sclerosis (ALS) is a motor neuron disease characterized by progressive degeneration of motor neurons. Mislocalization of TAR DNA-binding protein 43 (TDP-43) is an early event in the formation of cytoplasmic TDP-43-positive inclusions ...
Yu-Ju Liu, Hung-Chih Kuo, Yijuang Chern
doaj  

Targeting nuclear transporters in cancer: Diagnostic, prognostic and therapeutic potential [PDF]

, 2016
The Karyopherin superfamily is a major class of soluble transport receptors consisting of both import and export proteins. The trafficking of proteins involved in transcription, cell signalling and cell cycle regulation among other functions across the ...
Aggarwal, Albee, Alnabulsi, Alshareeda, Altan, Angus, Behrens, Bernis, Blower, Brinkmann, Brinkmann, Cansizoglu, Chang, Christiansen, Dahl, Das, Dasso, Depping, Dikovskaya, Forbes, Gluz, Gontan, Gorlich, Gousias, Gousias, Gousias, Grupp, Gruss, Hashimoto, Hintersteiner, Hu, Huang, Huang, Huang, Hutchins, Hügel, Ishizawa, Jensen, Jiang, Kahle, Kau, Kazim, Kim, Kimura, King, Knauer, Kojima, Kosugi, Kudo, Kurisaki, Kutay, Kuusisto, Kuusisto, Lapalombella, Latvia, Lau, Laurila, Li, Liang, Liao, Lin, Lin, Lorenzato, Ma, Marfori, Martens-de Kemp, Melo, Mortezavi, Mosammaparast, Muller, Nevins, Noske, Parikh, Poon, Pumroy, Quan, Quensel, Rensen, Sakai, Scherf, Shen, Shi, Shiraki, Sillje, Smith, Smith, Soderholm, Song, Stawerski, Stella Tsai, Stewart, Tai, Torgerson, Turner, Turner, Wagstaff, Wang, Wang, Wang, Watt, Watt, Watt, Wellmann, Wiese, Winkler, Winnepenninckx, Wu, Yan, Yang, Yao, Yoshitake, Yu, Zender, Zheng, Zhou, Zhu, Zhu, Zienkiewicz   +117 more
core   +1 more source

Respiratory virus modulation of host nucleocytoplasmic transport; target for therapeutic intervention?

Frontiers in Microbiology, 2015
The respiratory diseases caused by Rhinovirus, Respiratory Syncytial Virus and Influenza virus represent a large social and financial burden on healthcare worldwide.
Leon eCaly, Reena eGhildyal, David Andrew Jans   +2 more
doaj   +1 more source

Nuclear Transport: Beginning to Gel? [PDF]

Current Biology, 2012
The massive nuclear pore complex mediates nucleocytoplasmic traffic ranging from a single histone to a viral genome. To date, dissecting mechanism has been more an exercise in prediction than biochemical certainty. A recent study combines recombinant proteins with nuclei reconstituted in vitro to test predictions in a startlingly productive manner.
Douglass J. Forbes, Maureen A. Powers
openaire   +3 more sources

Variation in the nuclear effects of infection by different human rhinovirus serotypes.

Frontiers in Microbiology, 2015
Human rhinovirus (HRV) is a positive sense RNA virus, which, despite replicating in the cytoplasm, has a significant impact on nuclear transport and nuclear localisation of host proteins.
Erin Joanne Walker, Lora M Jensen, Sarah N Croft, Reena eGhildyal   +3 more
doaj   +1 more source