Results 1 to 10 of about 1,081 (139)

Putting things in place for fertilization: discovering roles for importin proteins in cell fate and spermatogenesis

Asian Journal of Andrology, 2015
Importin proteins were originally characterized for their central role in protein transport through the nuclear pores, the only intracellular entry to the nucleus.
Kate L. Loveland, Andrew T. Major, Romaly Butler, Julia C. Young, David A. Jans, Yoichi Miyamoto   +5 more
doaj   +1 more source

Nucleocytoplasmic transport defect in a North American patient with ALS8 [PDF]

, 2018
Robert D. Guber, Alice B. Schindler, Maher S. Budron, Ke‐lian Chen, Yuebing Li, Kenneth H. Fischbeck, Christopher Grunseich   +6 more
openalex   +1 more source

Strategies for the Viral Exploitation of Nuclear Pore Transport Pathways

Viruses
Viruses frequently exploit the host’s nucleocytoplasmic trafficking machinery to facilitate their replication and evade immune defenses. By encoding specialized proteins and other components, they strategically target host nuclear transport receptors ...
Xin Zhang, Keesiang Lim, Yujia Qiu, Masaharu Hazawa, Richard W. Wong   +4 more
doaj   +1 more source

Single-Molecule Studies of Nucleocytoplasmic Transport: from 1D to 3D [PDF]

, 2011
Weidong Yang
openalex   +1 more source

Aβ-driven nuclear pore complex dysfunction alters activation of necroptosis proteins in a mouse model of Alzheimer’s disease

eLife
The emergence of Aβ pathology is one of the hallmarks of Alzheimer’s disease (AD), but the mechanisms and impact of Aβ in progression of the disease is unclear.
Vibhavari Aysha Bansal, Jia Min Tan, Hui Rong Soon, Norliyana Zainolabidin, Takaomi Saido, Toh Hean Ch'ng   +5 more
doaj   +1 more source

Coupling of Perinuclear Actin Cap and Nuclear Mechanics in Regulating Flow‐Induced Yap Spatiotemporal Nucleocytoplasmic Transport

Advanced Science
Mechanical forces, including flow shear stress, govern fundamental cellular processes by modulating nucleocytoplasmic transport of transcription factors like Yes‐associated Protein (YAP). However, the underlying mechanical mechanism remains elusive.
Tianxiang Ma, Xiao Liu, Haoran Su, Qiusheng Shi, Yuan He, Fan Wu, Chenxing Gao, Kexin Li, Zhuqing Liang, Dongrui Zhang, Xing Zhang, Ke Hu, Shangyu Li, Li Wang, Min Wang, Shuhua Yue, Weili Hong, Xun Chen, Jing Zhang, Lisha Zheng, Xiaoyan Deng, Pu Wang, Yubo Fan   +22 more
doaj   +1 more source

Pre-ribosomal particles from nucleoli to cytoplasm

Nucleus
The analysis of nucleocytoplasmic transport of proteins and messenger RNA has been the focus of advanced microscopic approaches. Recently, it has been possible to identify and visualize individual pre-ribosomal particles on their way through the nuclear ...
Ulrich Kubitscheck, Jan Peter Siebrasse
doaj   +1 more source

Phosphorylation of Serine 399 in LKB1 Protein Short Form by Protein Kinase Cζ Is Required for Its Nucleocytoplasmic Transport and Consequent AMP-activated Protein Kinase (AMPK) Activation [PDF]

, 2013
Huaiping Zhu, Cate Moriasi, Miao Zhang, Yu Zhao, Ming-Hui Zou   +4 more
openalex   +1 more source

Increased nuclear import characterizes aberrant nucleocytoplasmic transport in neurons from patients with spinocerebellar ataxia type 7 [PDF]

Joshua G. Macopson-Jones, Marvin E. Adams, Julien Philippe, Albert R. La Spada   +3 more
openalex   +1 more source

A monoclonal antibody against the nuclear pore complex inhibits nucleocytoplasmic transport of protein and RNA in vivo. [PDF]

, 1988
Carol Featherstone, Martyn K. Darby, Larry Gerace   +2 more
openalex   +1 more source