Results 31 to 40 of about 15,740 (146)
Reversibility in nucleocytoplasmic transport [PDF]
Proceedings of the National Academy of Sciences, 2007 Nucleocytoplasmic exchange of proteins and RNAs is mediated by receptors that usher their cargo through the nuclear pores. Peptide localization signals on each cargo determine the receptors with which it will interact. Those interactions are normally regulated by the small GTPase Ran.
Ronen Benjamine, Kopito, Michael, Elbaum
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Nucleocytoplasmic transport: taking an inventory [PDF]
Cellular and Molecular Life Sciences (CMLS), 2003 ISSN:1420 ...
Fried, Howard, Kutay, Ulrike
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Controlling protein transport by small molecules [PDF]
, 2011 Many proteins are transported from the nucleus to the cytoplasm by the exportin CRM1, which recognizes cargo proteins through a leucine rich nuclear export signal (NES).
Karl Gademann, Gademann, Karl
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Reduction of dimensionality in Karyopherinβ1 mediated transport on FG domains [PDF]
, 2014 Many molecular transport processes in living cells proceed by facilitated diffusion in two dimensions instead of three, but how this process works remains poorly understood.
Schleicher, Kai D.
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Nucleocytoplasmic transport: A thermodynamic mechanism [PDF]
HFSP Journal, 2009 in press at HFSP Journal, vol 3 16 text pages, 1 table, 4 figures, plus Supplementary Material ...
Kopito, R. B., Elbaum, M.
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Organization and regulation of nucleocytoplasmic transport [PDF]
Molecular Biology, 2010 Separation of DNA replication and transcription, which occur in the nucleus, from protein synthesis, which occurs in the cytoplasm, allows a more precise regulation of these processes. Selective exchange of macromolecules between the two compartments is mediated by proteins of the nuclear pore complex (NPC).
Chumakov, S. P., Prassolov, V. S.
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NUCLEOCYTOPLASMIC TRANSPORT: The Soluble Phase [PDF]
Annual Review of Biochemistry, 1998 Active transport between the nucleus and cytoplasm involves primarily three classes of macromolecules: substrates, adaptors, and receptors. Some transport substrates bind directly to an import or an export receptor while others require one or more adaptors to mediate formation of a receptor-substrate complex.
I W, Mattaj, L, Englmeier
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GGGGCC repeat expansion in C9orf72 compromises nucleocytoplasmic transport [PDF]
, 2015 An unbiased genetic screen in Drosophila expressing G4C2-repeat-containing transcripts (repeats that in human cause pathogenesis in C9orf72-related neurological disease) finds genes that encode components of the nuclear pore and nucleocytoplasmic ...
Wong, Philip C +27 more
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Time-resolved biophysical approaches to nucleocytoplasmic transport [PDF]
, 2017 Molecules are continuously shuttling across the nuclear envelope barrier that separates the nucleus from the cytoplasm. Instead of being just a barrier to diffusion, the nuclear envelope is rather a complex filter that provides eukaryotes with an ...
Cardarelli, Francesco +1 more
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Structural and functional insights into nucleocytoplasmic transport [PDF]
, 2008 The cell nucleus is surrounded by a double membrane system, the nuclear envelope (NE), with the outer nuclear membrane being continuous with the endoplasmic reticulum.
Medalia, Ohad +3 more
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