Results 11 to 20 of about 15,740 (146)

The bioenergetics of nucleocytoplasmic transport. [PDF]

J Cell Biol
How nucleocytoplasmic transport (NCT) rates change due to cellular physiology-mediated fluctuations in GTP availability remains unclear. In this issue, Scott et al.
Luxton GWG.
europepmc   +6 more sources

Functional insights of nucleocytoplasmic transport in plants [PDF]

Frontiers in Plant Science, 2014
Plant nucleocytoplasmic transport beyond the nuclear envelope is important not only for basic cellular functions but also for growth, development, hormonal signaling, and responses to environmental stimuli. Key components of this transport system include
Kentaro Tamura, Ikuko Hara-Nishimura, Tamura Kentaro   +2 more
exaly   +2 more sources

Eukaryotic Ribosome assembly and Nucleocytoplasmic Transport. [PDF]

Methods Mol Biol, 2022
The process of eukaryotic ribosome assembly stretches across the nucleolus, the nucleoplasm and the cytoplasm, and therefore relies on efficient nucleocytoplasmic transport. In yeast, the import machinery delivers ~140,000 ribosomal proteins every minute
Oborská-Oplová M, Fischer U, Altvater M, Panse VG.   +3 more
europepmc   +2 more sources

Understanding the role of mechanics in nucleocytoplasmic transport. [PDF]

APL Bioeng, 2022
Cell nuclei are submitted to mechanical forces, which in turn affect nuclear and cell functions. Recent evidence shows that a crucial mechanically regulated nuclear function is nucleocytoplasmic transport, mediated by nuclear pore complexes (NPCs ...
Andreu I, Granero-Moya I, Garcia-Manyes S, Roca-Cusachs P.   +3 more
europepmc   +3 more sources

The Role of Nucleocytoplasmic Transport Defects in Amyotrophic Lateral Sclerosis. [PDF]

Int J Mol Sci, 2021
There is ample evidence that nucleocytoplasmic-transport deficits could play an important role in the pathology of amyotrophic lateral sclerosis (ALS).
Vanneste J, Van Den Bosch L.
europepmc   +2 more sources

Nucleocytoplasmic transport in apoptosis [PDF]

Cell Death & Differentiation, 2005
The apoptotic demolition of the nucleus is accomplished by diverse proapoptotic factors, most of which are activated in the cytoplasm and gain access to the nucleoplasm during the cell death process.
E Ferrando-May, Ferrando-May, Elisa
core   +4 more sources

Epigenetic Small Molecules Rescue Nucleocytoplasmic Transport and DNA Damage Phenotypes in C9ORF72 ALS/FTD. [PDF]

Brain Sci, 2021
Amyotrophic lateral sclerosis (ALS) is a progressive and fatal neurodegenerative disease with available treatments only marginally slowing progression or improving survival.
Ramic M, Andrade NS, Rybin MJ, Esanov R, Wahlestedt C, Benatar M, Zeier Z.   +6 more
europepmc   +2 more sources

Nucleocytoplasmic transport: Driving and directing transport [PDF]

Current Biology, 1998
Nucleocytoplasmic transport involves assembly and movement across the nuclear envelope of cargo-receptor complexes that interact with the small GTPase Ran.
Cole, C. N., Hammell, C. M.
core   +3 more sources

Nucleocytoplasmic transport senses mechanical forces independently of cell density in cell monolayers. [PDF]

J Cell Sci
Cells sense and respond to mechanical forces through mechanotransduction, which regulates processes in health and disease. In single adhesive cells, mechanotransduction involves the transmission of force from the extracellular matrix to the cell nucleus,
Granero-Moya I, Venturini V, Belthier G, Groenen B, Molina-Jordán M, González-Martín M, Trepat X, van Rheenen J, Andreu I, Roca-Cusachs P.   +9 more
europepmc   +2 more sources

RBM20 phosphorylation and its role in nucleocytoplasmic transport and cardiac pathogenesis. [PDF]

FASEB J, 2022
Arginine-serine (RS) domain(s) in splicing factors are critical for protein-protein interaction in pre-mRNA splicing. Phosphorylation of RS domain is important for splicing control and nucleocytoplasmic transport in the cell. RNA-binding motif 20 (RBM20)
Zhang Y, Wang C, Sun M, Jin Y, Braz CU, Khatib H, Hacker TA, Liss M, Gotthardt M, Granzier H, Ge Y, Guo W.   +11 more
europepmc   +2 more sources