Functional insights of nucleocytoplasmic transport in plants [PDF]
Frontiers in Plant Science, 2014 Plant nucleocytoplasmic transport beyond the nuclear envelope is important not only for basic cellular functions but also for growth, development, hormonal signalling, and responses to environmental stimuli.
Kentaro eTamura, Ikuko eHara-Nishimura
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Quantitative Nucleocytoplasmic Transport Assays in Cellular Models of Neurodegeneration
Bio-Protocol, 2020 Nucleocytoplasmic transport deficits are suggested to play a role in neurodegenerative disorders, including amyotrophic lateral sclerosis (ALS). Given the importance and complexity of this process, understanding when these aberrations occur and which ...
Joni Vanneste +4 more
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Spatiotemporal dynamics of nucleocytoplasmic transport [PDF]
Physical Review ResearchNucleocytoplasmic transport is essential for cellular function, presenting a canonical example of rapid molecular sorting inside cells. It consists of a coordinated interplay between import/export of molecules in/out the cell nucleus.
S. Alex Rautu +2 more
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Time-resolved biophysical approaches to nucleocytoplasmic transport [PDF]
Computational and Structural Biotechnology Journal, 2017 Molecules are continuously shuttling across the nuclear envelope barrier that separates the nucleus from the cytoplasm. Instead of being just a barrier to diffusion, the nuclear envelope is rather a complex filter that provides eukaryotes with an ...
Francesco Cardarelli
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Functional networks of nucleocytoplasmic transport-related genes differentiate ischemic and dilated cardiomyopathies. A new therapeutic opportunity. [PDF]
PLoS ONE, 2014 Heart failure provokes alterations in the expression of nucleocytoplasmic transport-related genes. To elucidate the nucleocytoplasmic transport-linked functional network underlying the two major causes of heart failure, ischemic cardiomyopathy (ICM) and ...
María Micaela Molina-Navarro +6 more
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Efficiency, selectivity, and robustness of nucleocytoplasmic transport. [PDF]
PLoS Computational Biology, 2007 All materials enter or exit the cell nucleus through nuclear pore complexes (NPCs), efficient transport devices that combine high selectivity and throughput. NPC-associated proteins containing phenylalanine-glycine repeats (FG nups) have large, flexible,
Anton Zilman +4 more
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Traffic jam at the nuclear pore: All roads lead to nucleocytoplasmic transport defects in ALS/FTD
Neurobiology of Disease, 2020 Amyotrophic lateral sclerosis (ALS) is a fatal late-onset neurodegenerative disease that specifically affects the function and survival of spinal and cortical motor neurons.
Claudia Fallini +3 more
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The Role of Nucleocytoplasmic Transport Defects in Amyotrophic Lateral Sclerosis. [PDF]
Int J Mol Sci, 2021 There is ample evidence that nucleocytoplasmic-transport deficits could play an important role in the pathology of amyotrophic lateral sclerosis (ALS).
Vanneste J, Van Den Bosch L.
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The bioenergetics of nucleocytoplasmic transport. [PDF]
J Cell BiolHow nucleocytoplasmic transport (NCT) rates change due to cellular physiology-mediated fluctuations in GTP availability remains unclear. In this issue, Scott et al.
Luxton GWG.
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Eukaryotic Ribosome assembly and Nucleocytoplasmic Transport. [PDF]
Methods Mol Biol, 2022 The process of eukaryotic ribosome assembly stretches across the nucleolus, the nucleoplasm and the cytoplasm, and therefore relies on efficient nucleocytoplasmic transport. In yeast, the import machinery delivers ~140,000 ribosomal proteins every minute
Oborská-Oplová M +3 more
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