Functional insights of nucleocytoplasmic transport in plants
Frontiers in Plant Science, 2014 Plant nucleocytoplasmic transport beyond the nuclear envelope is important not only for basic cellular functions but also for growth, development, hormonal signalling, and responses to environmental stimuli.
Kentaro eTamura, Ikuko eHara-Nishimura
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Functional networks of nucleocytoplasmic transport-related genes differentiate ischemic and dilated cardiomyopathies. A new therapeutic opportunity. [PDF]
PLoS ONE, 2014 Heart failure provokes alterations in the expression of nucleocytoplasmic transport-related genes. To elucidate the nucleocytoplasmic transport-linked functional network underlying the two major causes of heart failure, ischemic cardiomyopathy (ICM) and ...
María Micaela Molina-Navarro +6 more
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Evolutionarily Conserved Sequence Features Regulate the Formation of the FG Network at the Center of the Nuclear Pore Complex. [PDF]
, 2015 The nuclear pore complex (NPC) is the portal for bidirectional transportation of cargos between the nucleus and the cytoplasm. While most of the structural elements of the NPC, i.e.
Lee, BL +3 more
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Role of Nucleoporins and Transport Receptors in Cell Differentiation
Frontiers in Physiology, 2020 Bidirectional molecular movements between the nucleus and cytoplasm take place through nuclear pore complexes (NPCs) embedded in the nuclear membrane.
Asmat Ullah Khan +3 more
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Exo70-Mediated Recruitment of Nucleoporin Nup62 at the Leading Edge of Migrating Cells is Required for Cell Migration [PDF]
, 2009 Nucleoporin Nup62 localizes at the central channel of the nuclear pore complex and is essential for nucleocytoplasmic transport. Through its FG-repeat domain, Nup62 regulates nuclear pore permeability and binds nuclear transport receptors.
Bayliss +61 more
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GAP activity, but not subcellular targeting, is required for Arabidopsis RanGAP cellular and developmental functions [PDF]
, 2015 The Ran GTPase activating protein (RanGAP) is important to Ran signaling involved in nucleocytoplasmic transport, spindle organization, and postmitotic nuclear assembly.
Boruc, Joanna +6 more
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Impaired Nuclear Export of Polyglutamine-Expanded Androgen Receptor in Spinal and Bulbar Muscular Atrophy. [PDF]
, 2019 Spinal and bulbar muscular atrophy (SBMA) is a neuromuscular disease caused by polyglutamine (polyQ) expansion in the androgen receptor (AR). Prior studies have highlighted the importance of AR nuclear localization in SBMA pathogenesis; therefore, in ...
Arnold, Frederick J. +2 more
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Frontiers in Microbiology, 2022 The nuclear localization signal (NLS) and nuclear export signal (NES) are key signatures of proteins for controlling nuclear import and export. The NIb protein of turnip mosaic virus (TuMV) is an RNA-dependent RNA polymerase (RdRP) that is absolutely ...
Mingzhen Zhang +11 more
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Nucleolar Localization of HIV-1 Rev Is Required, Yet Insufficient for Production of Infectious Viral Particles. [PDF]
, 2018 Combination antiretroviral therapy fails in complete suppression of HIV-1 due to drug resistance and persistent latency. Novel therapeutic intervention requires knowledge of intracellular pathways responsible for viral replication, specifically those ...
Arizala, Jerlisa Ann C +5 more
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Nucleocytoplasmic transport: A thermodynamic mechanism [PDF]
HFSP Journal, 2009 in press at HFSP Journal, vol 3 16 text pages, 1 table, 4 figures, plus Supplementary Material ...
Kopito, R. B., Elbaum, M.
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