Results 21 to 30 of about 14,540 (195)
SCARB1 downregulation in adrenal insufficiency with Allgrove syndrome
Background Allgrove disease is a rare genetic syndrome characterized by adrenal insufficiency, alacrimia, achalasia and complex neurological involvement.
Giacomo Bitetto +9 more
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Nucleocytoplasmic transport: taking an inventory [PDF]
ISSN:1420 ...
Fried, Howard, Kutay, Ulrike
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Functional networks of nucleocytoplasmic transport-related genes differentiate ischemic and dilated cardiomyopathies. A new therapeutic opportunity. [PDF]
Heart failure provokes alterations in the expression of nucleocytoplasmic transport-related genes. To elucidate the nucleocytoplasmic transport-linked functional network underlying the two major causes of heart failure, ischemic cardiomyopathy (ICM) and ...
María Micaela Molina-Navarro +6 more
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Nucleocytoplasmic transport: A thermodynamic mechanism [PDF]
in press at HFSP Journal, vol 3 16 text pages, 1 table, 4 figures, plus Supplementary Material ...
Kopito, R. B., Elbaum, M.
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Role of Nucleoporins and Transport Receptors in Cell Differentiation
Bidirectional molecular movements between the nucleus and cytoplasm take place through nuclear pore complexes (NPCs) embedded in the nuclear membrane.
Asmat Ullah Khan +3 more
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Organization and regulation of nucleocytoplasmic transport [PDF]
Separation of DNA replication and transcription, which occur in the nucleus, from protein synthesis, which occurs in the cytoplasm, allows a more precise regulation of these processes. Selective exchange of macromolecules between the two compartments is mediated by proteins of the nuclear pore complex (NPC).
Chumakov, S. P., Prassolov, V. S.
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Nucleocytoplasmic transport in apoptosis [PDF]
The apoptotic demolition of the nucleus is accomplished by diverse proapoptotic factors, most of which are activated in the cytoplasm and gain access to the nucleoplasm during the cell death process. The nucleus is also the main target for genotoxic insult, a potent apoptotic trigger.
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The nuclear localization signal (NLS) and nuclear export signal (NES) are key signatures of proteins for controlling nuclear import and export. The NIb protein of turnip mosaic virus (TuMV) is an RNA-dependent RNA polymerase (RdRP) that is absolutely ...
Mingzhen Zhang +11 more
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The respiratory diseases caused by Rhinovirus, Respiratory Syncytial Virus and Influenza virus represent a large social and financial burden on healthcare worldwide.
Leon eCaly +2 more
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Role of molecular charge in nucleocytoplasmic transport. [PDF]
Transport of genetic materials and proteins between the nucleus and cytoplasm of eukaryotic cells is mediated by nuclear pore complexes (NPCs). A selective barrier formed by phenylalanine-glycine (FG) nucleoporins (Nups) with net positive charges in the ...
Alexander Goryaynov, Weidong Yang
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