Results 21 to 30 of about 14,540 (195)

SCARB1 downregulation in adrenal insufficiency with Allgrove syndrome

open access: yesOrphanet Journal of Rare Diseases, 2023
Background Allgrove disease is a rare genetic syndrome characterized by adrenal insufficiency, alacrimia, achalasia and complex neurological involvement.
Giacomo Bitetto   +9 more
doaj   +1 more source

Nucleocytoplasmic transport: taking an inventory [PDF]

open access: yesCellular and Molecular Life Sciences (CMLS), 2003
ISSN:1420 ...
Fried, Howard, Kutay, Ulrike
openaire   +3 more sources

Functional networks of nucleocytoplasmic transport-related genes differentiate ischemic and dilated cardiomyopathies. A new therapeutic opportunity. [PDF]

open access: yesPLoS ONE, 2014
Heart failure provokes alterations in the expression of nucleocytoplasmic transport-related genes. To elucidate the nucleocytoplasmic transport-linked functional network underlying the two major causes of heart failure, ischemic cardiomyopathy (ICM) and ...
María Micaela Molina-Navarro   +6 more
doaj   +1 more source

Nucleocytoplasmic transport: A thermodynamic mechanism [PDF]

open access: yesHFSP Journal, 2009
in press at HFSP Journal, vol 3 16 text pages, 1 table, 4 figures, plus Supplementary Material ...
Kopito, R. B., Elbaum, M.
openaire   +3 more sources

Role of Nucleoporins and Transport Receptors in Cell Differentiation

open access: yesFrontiers in Physiology, 2020
Bidirectional molecular movements between the nucleus and cytoplasm take place through nuclear pore complexes (NPCs) embedded in the nuclear membrane.
Asmat Ullah Khan   +3 more
doaj   +1 more source

Organization and regulation of nucleocytoplasmic transport [PDF]

open access: yesMolecular Biology, 2010
Separation of DNA replication and transcription, which occur in the nucleus, from protein synthesis, which occurs in the cytoplasm, allows a more precise regulation of these processes. Selective exchange of macromolecules between the two compartments is mediated by proteins of the nuclear pore complex (NPC).
Chumakov, S. P., Prassolov, V. S.
openaire   +3 more sources

Nucleocytoplasmic transport in apoptosis [PDF]

open access: yesCell Death & Differentiation, 2005
The apoptotic demolition of the nucleus is accomplished by diverse proapoptotic factors, most of which are activated in the cytoplasm and gain access to the nucleoplasm during the cell death process. The nucleus is also the main target for genotoxic insult, a potent apoptotic trigger.
openaire   +3 more sources

Nuclear Exportin 1 (XPO1) Binds to the Nuclear Localization/Export Signal of the Turnip Mosaic Virus NIb to Promote Viral Infection

open access: yesFrontiers in Microbiology, 2022
The nuclear localization signal (NLS) and nuclear export signal (NES) are key signatures of proteins for controlling nuclear import and export. The NIb protein of turnip mosaic virus (TuMV) is an RNA-dependent RNA polymerase (RdRP) that is absolutely ...
Mingzhen Zhang   +11 more
doaj   +1 more source

Respiratory virus modulation of host nucleocytoplasmic transport; target for therapeutic intervention?

open access: yesFrontiers in Microbiology, 2015
The respiratory diseases caused by Rhinovirus, Respiratory Syncytial Virus and Influenza virus represent a large social and financial burden on healthcare worldwide.
Leon eCaly   +2 more
doaj   +1 more source

Role of molecular charge in nucleocytoplasmic transport. [PDF]

open access: yesPLoS ONE, 2014
Transport of genetic materials and proteins between the nucleus and cytoplasm of eukaryotic cells is mediated by nuclear pore complexes (NPCs). A selective barrier formed by phenylalanine-glycine (FG) nucleoporins (Nups) with net positive charges in the ...
Alexander Goryaynov, Weidong Yang
doaj   +1 more source

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