Results 121 to 130 of about 6,360 (219)
Nature Communications, 2020 The nuclear pore complex components, nucleoporins, have been proposed to mediate spatial and temporal organization of chromatin. Here, the authors show that Nucleoporin 153 interacts with CTCF and cohesin, and mediates their binding across cis-regulatory
Shinichi Kadota +5 more
doaj +1 more source
Molecular architecture of the yeast nuclear pore complex: Localization of Nsp1p subcomplexes [PDF]
, 1998 info:eu-repo/semantics ...
Aebi, U. +11 more
core +1 more source
Bending or Building: Multifaceted Functions of Amphipathic Helices in Basket Nucleoporins.
, 2015 International audienceRecently reporting in Developmental Cell, Mészáros et al. (2015) and Vollmer et al. (2015) extend the inventory of membrane-binding and -bending nuclear pore proteins to peripheral nucleoporins localized at the nuclear ...
Doye, Valérie +3 more
core +1 more source
Nucleoporins and Protein Transport in Drosophila
, 2006 Many biological responses rely on the selective translocation of transcriptional regulators in and out of the nucleus through nuclear pore complexes (NPC). More than one million macromolecules per minute pass through the NPC and an important challenge is
Samakovlis, Christos, +2 more
core
Cse1p-Binding Dynamics Reveal a Binding Pattern for FG-Repeat Nucleoporins on Transport Receptors
, 2007 SummaryNuclear pore proteins with phenylalanine-glycine repeats are vital to the functional transport of molecules across the nuclear pore complex. The current study investigates the binding of these FG-nucleoporins to the Cse1p:Kap60p:RanGTP nuclear ...
Schulten, Klaus, Isgro, Timothy A.
core +1 more source
Nature Communications, 2018 Genomic imprinting restricts transcription to predominantly one parental allele. Here the authors perform a screen for epigenetic factors involved in paternal allelic silencing at the Kcnq1ot1 imprinted domain in mouse extraembryonic endoderm stem cells ...
Saqib S. Sachani +6 more
doaj +1 more source
Mitotic Phosphorylation of Nucleoporins: Dismantling NPCs and Beyond [PDF]
Developmental Cell, 2011 Recently reporting in Cell, Laurell et al. (2011) demonstrate that the hyperphosphorylation of vertebrate Nup98 by distinct mitotic kinases contributes to its release from nuclear pores, drives nuclear envelope permeabilization, and may provide a molecular switch coordinating nuclear envelope breakdown and spindle formation.
openaire +2 more sources
Nucleoporins are evolving rapidly in Saccharomyces yeasts.
, 2018 (A) Results of published high-throughput genetic screens for host factors affecting Ty mobility [51,52,55–57]. Only nucleoporin genes found in these screens are summarized, where disruption of the indicated gene altered Ty3 or Ty1 mobility.
Suzanne B. Sandmeyer (5142641) +3 more
core +1 more source
, 2012 The mechanism for nuclear envelope (NE) assembly is not fully understood. Importin-ß and the small GTPase Ran have been implicated in the spatial regulation of NE assembly process.
Guo, Li +17 more
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eLife, 2013 Nucleocytoplasmic transport is mediated by nuclear pore complexes (NPCs) embedded in the nuclear envelope. About 30 different proteins (nucleoporins, nups) arrange around a central eightfold rotational axis to build the modular NPC. Nup188 and Nup192 are
Kasper R Andersen +8 more
doaj +1 more source