Results 111 to 120 of about 6,849 (214)
Coarse-grained Theory and Simulation of Assemblies of Intrinsically-disordered Nucleoporins [PDF]
Selective import and export through the nuclear envelope in the eukaryotic cell is solely regulated by the transporter known as Nuclear Pore Complex (NPC).
Gu, Chad
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Genomic imprinting restricts transcription to predominantly one parental allele. Here the authors perform a screen for epigenetic factors involved in paternal allelic silencing at the Kcnq1ot1 imprinted domain in mouse extraembryonic endoderm stem cells ...
Saqib S. Sachani +6 more
doaj +1 more source
Mitotic Phosphorylation of Nucleoporins: Dismantling NPCs and Beyond [PDF]
Recently reporting in Cell, Laurell et al. (2011) demonstrate that the hyperphosphorylation of vertebrate Nup98 by distinct mitotic kinases contributes to its release from nuclear pores, drives nuclear envelope permeabilization, and may provide a molecular switch coordinating nuclear envelope breakdown and spindle formation.
openaire +2 more sources
Since the first report about cytoplasmic nucleophosmin (NPM) in acute myelogenous leukemia with a normal karyotype was announced, the shuttling activity of NPM and its proper subcellular localization have drawn many attentions.
Wu, Q, Shu, W, Cui, G, Chen, Y, Li, R
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Nucleoporin-Related Leukemia: Nucleoporin rearrangements and their impact on nucleocytoplasmic transport and the proteome [PDF]
Doctorat en ...
openaire
NDC1 : a crucial membrane-integral nucleoporin of metazoan nuclear pore complexes [PDF]
POM121 and gp210 were, until this point, the only known membrane-integral nucleoporins (Nups) of vertebrates and, thus, the only candidate anchors for nuclear pore complexes (NPCs) within the nuclear membrane. In an accompanying study (Stavru et al.), we
Gorlich, D. +19 more
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Functional Genomics Evidence Unearths New Moonlighting Roles of Outer Ring Coat Nucleoporins
Data supplements for the manuscript "Functional Genomics Evidence Unearths New Moonlighting Roles of Outer Ring Coat Nucleoporins" by Katerina R. Katsani, Manuel Irimia, Christos Karapiperis, Zacharias G. Scouras, Benjamin J.
Christos Ouzounis (479064)
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The nuclear pore complex (NPC) is the sole gateway for molecular transport between the nucleus and the cytoplasm in eukaryotes. The NPC is composed of approximately 30 different kinds of protein components called nucleoporins. The functional structure of
Yasushi Hiraoka +2 more
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Quantifications of the PI fluorescences with the mean values and the 95% confidence intervals (bars) after addition of 300 genome-containing wt AAV2 particles and 300 mutant AAV2 per permeabilized HeLa cell.
Harald Wodrich (7272) +10 more
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Inner ring, outer ring, and central channel nucleoporins localize to the base of motile cilia.
(A) RPE-1 cells were stained with antibodies to the channel nucleoporin Nup62 (gray). (B-E) Epithelial cells isolated from rat trachea were stained with antibodies against (b) the channel nucleoporin Nup62, (C) the inner ring nucleoporin Nup98, or the ...
Daisuke Takao (115457) +2 more
core +1 more source

