Results 111 to 120 of about 6,849 (214)

Coarse-grained Theory and Simulation of Assemblies of Intrinsically-disordered Nucleoporins [PDF]

open access: yes, 2019
Selective import and export through the nuclear envelope in the eukaryotic cell is solely regulated by the transporter known as Nuclear Pore Complex (NPC).
Gu, Chad
core   +1 more source

Nucleoporin 107, 62 and 153 mediate Kcnq1ot1 imprinted domain regulation in extraembryonic endoderm stem cells

open access: yesNature Communications, 2018
Genomic imprinting restricts transcription to predominantly one parental allele. Here the authors perform a screen for epigenetic factors involved in paternal allelic silencing at the Kcnq1ot1 imprinted domain in mouse extraembryonic endoderm stem cells ...
Saqib S. Sachani   +6 more
doaj   +1 more source

Mitotic Phosphorylation of Nucleoporins: Dismantling NPCs and Beyond [PDF]

open access: yesDevelopmental Cell, 2011
Recently reporting in Cell, Laurell et al. (2011) demonstrate that the hyperphosphorylation of vertebrate Nup98 by distinct mitotic kinases contributes to its release from nuclear pores, drives nuclear envelope permeabilization, and may provide a molecular switch coordinating nuclear envelope breakdown and spindle formation.
openaire   +2 more sources

Deguelin represses both the expression of nucleophosmin and some nucleoporins: Nup88 and Nup214 in Jurkat cells

open access: yes, 2008
Since the first report about cytoplasmic nucleophosmin (NPM) in acute myelogenous leukemia with a normal karyotype was announced, the shuttling activity of NPM and its proper subcellular localization have drawn many attentions.
Wu, Q, Shu, W, Cui, G, Chen, Y, Li, R
core   +1 more source

NDC1 : a crucial membrane-integral nucleoporin of metazoan nuclear pore complexes [PDF]

open access: yes, 2006
POM121 and gp210 were, until this point, the only known membrane-integral nucleoporins (Nups) of vertebrates and, thus, the only candidate anchors for nuclear pore complexes (NPCs) within the nuclear membrane. In an accompanying study (Stavru et al.), we
Gorlich, D.   +19 more
core   +1 more source

Functional Genomics Evidence Unearths New Moonlighting Roles of Outer Ring Coat Nucleoporins

open access: yes, 2014
Data supplements for the manuscript "Functional Genomics Evidence Unearths New Moonlighting Roles of Outer Ring Coat Nucleoporins" by Katerina R. Katsani, Manuel Irimia, Christos Karapiperis, Zacharias G. Scouras, Benjamin J.
Christos Ouzounis (479064)
core   +1 more source

Newly found Tetrahymena nucleoporins, Nup214, Nup153 and Pom121/Pom82, differentiate nuclear pore complexes of functionally distinct nuclei

open access: yes, 2018
The nuclear pore complex (NPC) is the sole gateway for molecular transport between the nucleus and the cytoplasm in eukaryotes. The NPC is composed of approximately 30 different kinds of protein components called nucleoporins. The functional structure of
Yasushi Hiraoka   +2 more
core   +1 more source

A. Impact of VP1u on NEBD.

open access: yes, 2013
Quantifications of the PI fluorescences with the mean values and the 95% confidence intervals (bars) after addition of 300 genome-containing wt AAV2 particles and 300 mutant AAV2 per permeabilized HeLa cell.
Harald Wodrich (7272)   +10 more
core   +1 more source

Inner ring, outer ring, and central channel nucleoporins localize to the base of motile cilia.

open access: yes, 2019
(A) RPE-1 cells were stained with antibodies to the channel nucleoporin Nup62 (gray). (B-E) Epithelial cells isolated from rat trachea were stained with antibodies against (b) the channel nucleoporin Nup62, (C) the inner ring nucleoporin Nup98, or the ...
Daisuke Takao (115457)   +2 more
core   +1 more source

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