Results 91 to 100 of about 5,346 (178)

Simple biophysics underpins collective conformations of the intrinsically disordered proteins of the Nuclear Pore Complex

eLife, 2016
Nuclear Pore Complexes (NPCs) are key cellular transporter that control nucleocytoplasmic transport in eukaryotic cells, but its transport mechanism is still not understood.
Andrei Vovk, Chad Gu, Michael G Opferman, Larisa E Kapinos, Roderick YH Lim, Rob D Coalson, David Jasnow, Anton Zilman   +7 more
doaj   +1 more source

NUP155 and NDC1 interaction in NSCLC: a promising target for tumor progression

Frontiers in Pharmacology
BackgroundNUP155 was reported to involve breast invasive carcinoma and hepatocellular carcinoma. We hypothesized that NUP155 and NDC1impacted the progression of NSCLC.MethodsThe dataset was analyzed to find differentially expressed genes.
Kai-Min Li, Li-Fei Meng, Zhi-Hao Yang, Wen-Tao Hu   +3 more
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Nucleoporin 153 links nuclear pore complex to chromatin architecture by mediating CTCF and cohesin binding

Nature Communications, 2020
The nuclear pore complex components, nucleoporins, have been proposed to mediate spatial and temporal organization of chromatin. Here, the authors show that Nucleoporin 153 interacts with CTCF and cohesin, and mediates their binding across cis-regulatory
Shinichi Kadota, Jianhong Ou, Yuming Shi, Jeannie T. Lee, Jiayu Sun, Eda Yildirim   +5 more
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Nucleoporin 107, 62 and 153 mediate Kcnq1ot1 imprinted domain regulation in extraembryonic endoderm stem cells

Nature Communications, 2018
Genomic imprinting restricts transcription to predominantly one parental allele. Here the authors perform a screen for epigenetic factors involved in paternal allelic silencing at the Kcnq1ot1 imprinted domain in mouse extraembryonic endoderm stem cells ...
Saqib S. Sachani, Lauren S. Landschoot, Liyue Zhang, Carlee R. White, William A. MacDonald, Michael C. Golding, Mellissa R. W. Mann   +6 more
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Mitotic Phosphorylation of Nucleoporins: Dismantling NPCs and Beyond [PDF]

Developmental Cell, 2011
Recently reporting in Cell, Laurell et al. (2011) demonstrate that the hyperphosphorylation of vertebrate Nup98 by distinct mitotic kinases contributes to its release from nuclear pores, drives nuclear envelope permeabilization, and may provide a molecular switch coordinating nuclear envelope breakdown and spindle formation.
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Newly found Tetrahymena nucleoporins, Nup214, Nup153 and Pom121/Pom82, differentiate nuclear pore complexes of functionally distinct nuclei

Communicative & Integrative Biology, 2018
The nuclear pore complex (NPC) is the sole gateway for molecular transport between the nucleus and the cytoplasm in eukaryotes. The NPC is composed of approximately 30 different kinds of protein components called nucleoporins. The functional structure of
Masaaki Iwamoto, Yasushi Hiraoka, Tokuko Haraguchi   +2 more
doaj   +1 more source

Nucleoporin-Related Leukemia: Nucleoporin rearrangements and their impact on nucleocytoplasmic transport and the proteome [PDF]

, 2020
Doctorat en ...
openaire  

Nucleoporin [PDF]

, 2020
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A nucleoporin that facilitates meiotic kinetochore reorganization [PDF]

Cell Cycle, 2016
Hui-Ju, Yang, Tokuko, Haraguchi, Yasushi, Hiraoka   +2 more
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Corrigendum: Protein Subdomain Enrichment of NUP155 Variants Identify a Novel Predicted Pathogenic Hotspot

Frontiers in Cardiovascular Medicine, 2020
Riley J. Leonard, Riley J. Leonard, Claudia C. Preston, Melanie E. Gucwa, Melanie E. Gucwa, Yohannes Afeworki, Arielle S. Selya, Randolph S. Faustino, Randolph S. Faustino   +8 more
doaj   +1 more source