Results 91 to 100 of about 6,360 (219)
Nucleoporin Nup62 maintains centrosome homeostasis [PDF]
Cell Cycle, 2013 Centrosomes are comprised of 2 orthogonally arranged centrioles surrounded by the pericentriolar material (PCM), which serves as the main microtubule organizing center of the animal cell. More importantly, centrosomes also control spindle polarity and orientation during mitosis.
Hashizume, Chieko +5 more
openaire +2 more sources
HIV Nuclear Entry: Clearing the Fog
Viruses, 2010 HIV-1 and other lentiviruses have the unusual capability of infecting nondividing cells, but the mechanism by which they cross an intact nuclear membrane is mysterious.
Vaibhav B. Shah, Christopher Aiken
doaj +1 more source
The FASEB Journal, Volume 40, Issue 9, 15 May 2026.Cell wall stress in yeast triggers transcriptional reprogramming through the CWI pathway. This study identifies Sus1, a subunit of SAGA and TREX‐2, as a key regulator in this process. Sus1 associates with stress‐responsive genes, promoting pre‐initiation complex assembly, chromatin remodeling, and RNA Pol II progression independently of H2B ...
Mónica Pavón‐Vergés +4 more
wiley +1 more source
NUP214 (nucleoporin 214kDa) [PDF]
Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2011 Review on NUP214 (nucleoporin 214kDa), with data on DNA, on the protein encoded, and where the gene is implicated.
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Annulate Lamellae Play Only a Minor Role in the Storage of Excess Nucleoporins in Drosophila Embryos
, 2004 The nuclear pore complexes (NPCs), multiprotein assemblies embedded in the nuclear envelope, conduct nucleo-cytoplasmic traffic of macromolecules.
Kiseleva, E V, +14 more
core +1 more source
Intercompartmental communication in senescence
FEBS Open Bio, Volume 16, Issue 5, Page 837-856, May 2026.Senescent cells experience structural changes in the plasma membrane, endoplasmic reticulum, mitochondria, lysosomes, nucleus, and cytoskeleton. These alterations disrupt crosstalk among cellular compartments, impairing vesicular trafficking, contact sites, and molecular flow.
Krystyna Mazan‐Mamczarz +3 more
wiley +1 more source
Two structurally distinct domains of the nucleoporin Nup170 cooperate to tether a subset of nucleoporins to nuclear pores [PDF]
Journal of Cell Biology, 2009 How individual nucleoporins (Nups) perform their role in nuclear pore structure and function is largely unknown. In this study, we examined the structure of purified Nup170 to obtain clues about its function. We show that Nup170 adopts a crescent moon shape with two structurally distinct and separable domains, a β-propeller N terminus and an α-solenoid
Flemming, Dirk +5 more
openaire +3 more sources
Characterization of the cellular functions of the nucleoporins Nup153 and Nup88 [PDF]
, 2010 Characterization of the Cellular Functions of the Nucleoporins Nup153 and Nup88 PhD Thesis, Yvonne Christine Lussi, 2010, University of Basel Nuclear pore complexes (NPCs) and nuclear lamins are major constituents of the nuclear envelope (NE) in ...
Lussi, Yvonne Christine
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NUP155 and NDC1 interaction in NSCLC: a promising target for tumor progression
Frontiers in PharmacologyBackgroundNUP155 was reported to involve breast invasive carcinoma and hepatocellular carcinoma. We hypothesized that NUP155 and NDC1impacted the progression of NSCLC.MethodsThe dataset was analyzed to find differentially expressed genes.
Kai-Min Li +3 more
doaj +1 more source
Advanced Science, Volume 13, Issue 25, 4 May 2026.Tumor metastasis results from complex interactions between cancer cells and mechanical microenvironments. We propose a “nucleus‐centered, cross‐stage mechanical signal decoding” model, highlighting how nuclear mechanosensors interpret forces at different stages.
Linqi Song +4 more
wiley +1 more source