Results 91 to 100 of about 6,849 (214)

NLS‐mediated NPC functions of the nucleoporin Pom121 [PDF]

FEBS Letters, 2010
MINT‐7951306, MINT‐7951362: pom121 (uniprotkb:Q5EWX9) physically interacts (MI:0914) with nup155 (uniprotkb:Q7ZWL0), nup160 (uniprotkb:P83722), nup93 (uniprotkb:Q7ZX96), Importin beta (uniprotkb:P52297) and nup62 (uniprotkb:Q91349) by pull down (MI:0096)
Yavuz, Sevil, Santarella-Mellwig, Rachel, Koch, Birgit, Jaedicke, Andreas, Mattaj, Iain W., Antonin, Wolfram   +5 more
openaire   +2 more sources

The Genome and Population Structure of the Spruce Beetle, Dendroctonus rufipennis (Kirby, 1837), a Transcontinental Pest of North American Spruce

Molecular Ecology Resources, Volume 26, Issue 8, November 2026.
ABSTRACT The spruce bark beetle Dendroctonus rufipennis (Family: Curculionidae; Subfamily Scolytinae) is a major forest insect pest throughout the transcontinental range of spruce species (Picea spp.) in North America. Here, we present an annotated, near chromosome‐level, genome assembly of 271 Mb, with 86% of the assembly contained in 16 ...
Erin O. Campbell, Philip D. Batista, Véronique Lévesque‐Tremblay, Catherine Béliveau, Kathia Bernier, Kateryna Romanenko, Ward B. Strong, Katherine P. Bleiker, Dezene P. W. Huber, Christopher I. Keeling   +9 more
wiley   +1 more source

Nucleoporin Gene Fusions and Hematopoietic Malignancies [PDF]

New Journal of Science, 2014
Nuclear pore complexes (NPCs) are the sole gateways between the nucleus and the cytoplasm of eukaryotic cells and they mediate all macromolecular trafficking between these cellular compartments. Nucleocytoplasmic transport is highly selective and precisely regulated and as such an important aspect of normal cellular function. Defects in this process or
openaire   +2 more sources

Quizartinib Resistance Mutations and Treatment Outcomes in Relapsed or Refractory FLT3‐ITD–Positive AML

Cancer Science, Volume 117, Issue 11, Page 3108-3120, November 2026.
ABSTRACT Quizartinib is a FMS‐like tyrosine kinase 3 (FLT3) inhibitor indicated for FLT3 internal tandem duplication (FLT3‐ITD)–positive acute myeloid leukemia (AML). We aimed to evaluate quizartinib resistance mechanisms, in addition to efficacy and safety outcomes, in patients with relapsed or refractory FLT3‐ITD–positive AML.
Yuichiro Semba, Toshihiro Miyamoto, Senji Kasahara, Yoshikane Kikushige, Takahiro Maeda, Goichi Yoshimoto, Shuichi Ota, Akio Saito, Yuho Najima, Hiroki Hosoi, Daigo Niiya, Koji Kato, Koji Nagafuji, Takashi Akasaka, Tomohiko Kamimura, Atsushi Takita, Maiko Narahara, Tadashi Toki, Koichi Iwanaga, Koji Yonemoto, Mine Harada, Koichi Akashi   +21 more
wiley   +1 more source

Nuclear importin α1 AtIMPA1 regulates stomatal reopening to defend against Pst DC3000 by orchestrating ABA signaling

The Plant Journal, Volume 128, Issue 3, November 2026.
SUMMARY Importin α family proteins serve as essential carriers for transporting specific disease‐resistant proteins into the nucleus, enabling these proteins to function properly. However, whether importin α proteins are involved in plant immunity remains unclear.
Ting Zhang, Kang Wang, Yi Guan, Jingao Zhang, Charles Tetteh, Chenxi Liu, Cheng Zhang, Pinyuan Jin, Sheng Luo, Yiling Wang, Huajian Zhang   +10 more
wiley   +1 more source

Selective recruitment of nucleoporins on vaccinia virus factories and the role of Nup358 in viral infection

, 2017
Vaccinia virus (VACV), a member of the Poxviridae family, uses cytoplasmic factories for its replication. Recent studies indicated that VACV infection requires a set of nucleoporins.
Ashish Kamble, Renuka Nawadkar, Arvind Sahu, Singh, Aditi, Sahu, Arvind, Khuperkar, Deepak, Aditi Singh, Arya Ghate, Deepak Khuperkar, Kamble, Ashish, Ghate, Arya, Jomon Joseph, Nawadkar, Renuka, Joseph, Jomon   +13 more
core   +1 more source

Annulate Lamellae Play Only a Minor Role in the Storage of Excess Nucleoporins in Drosophila Embryos

, 2004
The nuclear pore complexes (NPCs), multiprotein assemblies embedded in the nuclear envelope, conduct nucleo-cytoplasmic traffic of macromolecules.
Kiseleva, E V,, Kieselbach, Thomas, Elena V. Kiseleva, Gubanova, Natalia V, Hallberg, Einar, Natalia V. Gubanova, Kieselbach, T,, Einar Hallberg, Kiseleva, Elena V, Hallberg, Einar,, Onischenko, Evgeny A, Evgeny A. Onischenko, Gubanova, N V,, Thomas Kieselbach, Onischenko, Evgeny A,   +14 more
core   +1 more source

Strategies for the Viral Exploitation of Nuclear Pore Transport Pathways

Viruses
Viruses frequently exploit the host’s nucleocytoplasmic trafficking machinery to facilitate their replication and evade immune defenses. By encoding specialized proteins and other components, they strategically target host nuclear transport receptors ...
Xin Zhang, Keesiang Lim, Yujia Qiu, Masaharu Hazawa, Richard W. Wong   +4 more
doaj   +1 more source

Single‐cell Transcriptome Profiling Reveals Gene Regulatory Networks and Key Genes in the Root Epidermis and Cortical Cells Associated with Early Nodulation in Glycine Max

Advanced Science, Volume 13, Issue 55, 5 October 2026.
Single‐cell transcriptomics of soybean roots soon after rhizobial inoculation reveals epidermal and cortical cell‐specific programs and gene‐regulatory networks acting in symbiosis establishment. We identify an ethylene‐driven regulatory circuit involving WRKY6.3/6.4 transcription factors targeting select Nod19 genes that promotes infection‐thread ...
Yongbin Zhuang, Yu Geng, Xinyu Guo, Chen Wang, Yongjing Sun, Luqi Liu, Li Liu, QianQian Gao, XinFang Zhu, Hongxiang Cao, Gengshuo Zhang, Yunxia Liu, Guobin Zhang, Baoyin Chen, Jinfei Zhang, Xin Hou, Xiaoming Li, Dajian Zhang   +17 more
wiley   +1 more source

The nucleoporin Nup88 is interacting with nuclear lamin A

Molecular Biology of the Cell, 2011
Nuclear pore complexes (NPCs) are embedded in the nuclear envelope (NE) and mediate bidirectional nucleocytoplasmic transport. Their spatial distribution in the NE is organized by the nuclear lamina, a meshwork of nuclear intermediate filament proteins. Major constituents of the nuclear lamina are A- and B-type lamins.
Lussi, Yvonne Y.C., Hügi, Ilona, Fahrenkrog, Birthe, Laurell, Eva Laurell E., Kutay, Ulrike   +4 more
openaire   +6 more sources