Results 131 to 140 of about 159,382 (166)

Rhamnose biosynthesis is not impaired by the deletion of putative <i>rfbC</i> genes, <i>slr0985</i> and <i>slr1933</i>, in <i>Synechocystis</i> sp. PCC 6803. [PDF]

open access: yesAppl Environ Microbiol
Pissarra J   +11 more
europepmc   +1 more source

Position-specific ORF nucleoside-ribose modifications enabled by complete chemical synthesis enhance mRNA stability and translation. [PDF]

open access: yesNat Commun
Iwai H   +16 more
europepmc   +1 more source
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Synthesis of Nonnatural Nucleoside Diphosphate Sugars

European Journal of Organic Chemistry, 2011
AbstractRecently, we reported an efficient chemical method for the synthesis of a variety of naturally occurring nucleoside diphosphate (NDP) sugars. This method, which is based on the cycloSal approach, can also be used, in principle, for the preparation of rare or even nonnatural NDP sugars. Herein, the syntheses of sulfoquinovose‐, glucose‐6‐sulfate‐
Chris Meier
exaly   +2 more sources

A kinetic study on the chemical cleavage of nucleoside diphosphate sugars

Carbohydrate Research, 2010
Nucleoside diphosphate sugars serve in essential roles in metabolic processes. They have, therefore, been used in mechanistic studies on glycosylation reactions, and their analogues have been synthesised as enzyme and receptor inhibitors. Despite extensive biochemical research, little is known about their chemical reactions.
Satu Mikkola
exaly   +3 more sources

Efficient and Rapid Synthesis of Nucleoside Diphosphate Sugars from Nucleoside Phosphorimidazolides

European Journal of Organic Chemistry, 2013
AbstractWe describe a simple, efficient, and protecting‐group‐free, magnesium‐chloride‐promoted synthesis of nucleoside diphosphate sugars from the corresponding nucleoside 5′‐phosphorimidazolides and sugar phosphates in DMF. After optimization, nine different nucleoside sugars were synthesized and isolated in 63–92 % yield, demonstrating the ...
Jacek Jemielity   +2 more
exaly   +2 more sources

A Simple Synthesis of Sugar Nucleoside Diphosphates by Chemical Coupling in Water

Angewandte Chemie International Edition, 2012
The use of glycosyltransferases in chemoenzymatic oligosaccharide synthesis is attractive, provided that the enzymes are available, since it eliminates the tedious multistep protectiondeprotection and chemical glycosylation procedure that characterizes classic chemical synthesis.
Hidenori, Tanaka   +4 more
openaire   +2 more sources

An improved method for the isolation of some nucleoside diphosphate sugars from yeast

Biochimica et Biophysica Acta, 1957
Abstract An improved method is described for the simultaneous isolation of UDPG, UDPAG and GDPM from yeast. The method involves extraction with ethanol and chromatography on anion exchange resin columns. The nucleotides are obtained from the effluent by adsorption on charcoal and subsequent elution with aqueous ethanol. A washing of the charcoal with
H G, PONTIS, E, CABIB, L F, LELOIR
openaire   +2 more sources

The Mechanism of Phosphorylation of Natural Nucleosides and Anti-HIV Analogues by Nucleoside Diphosphate Kinase Is Independent of Their Sugar Substituents

ChemBioChem, 2002
The reaction mechanism of the phosphoryl transfer catalyzed by dinucleoside diphosphate kinase from Dictyostelium discoideum is investigated by semiempirical AM1 molecular orbital computation of an active site model system on the basis of various X-ray crystallographic structures.
Michael C, Hutter, Volkhard, Helms
openaire   +3 more sources

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