Results 111 to 120 of about 69,179 (216)
ISDH‐seq: a robust methodology for profiling and characterization of open chromatin
Plant Biotechnology Journal, EarlyView.Summary Profiling of open chromatin is essential for understanding regulatory mechanisms that govern DNA‐templated events. However, methodology‐dependent detection of open chromatin sites (OCSs) has been reported in both humans and plants. Therefore, there is a pressing need for any reliable orthogonal methodologies to broaden the identification of ...
Zhaoguo Li +8 more
wiley +1 more source
Genomics‐assisted breeding for designing salinity‐smart future crops
Plant Biotechnology Journal, EarlyView.This review explores fast‐forward genomics‐assisted breeding tools to fast‐track the designing of salinity‐smart crops. Integration of various breeding tools can enhance salinity tolerance, ensuring sustainable agriculture and global food security. Summary Climate change induces many abiotic stresses, including soil salinity, significantly challenging ...
Ali Raza +6 more
wiley +1 more source
Factors determining chromosomal localization of transposable elements in plants
Plant Biology, EarlyView.We review transposon chromosomal niches, and the functional consequences of their specific chromosomal localization in plants. Abstract Transposable elements (TEs) constitute a significant part of plant genomes and shape their genomic landscape. While some TEs are ubiquitously dispersed, other elements specifically occupy discrete genomic loci.
E. Kejnovsky +3 more
wiley +1 more source
Integrated Disease Management, Adaptation and Genomics of Fungal Plant Pathogens in Cropping Systems
Plant Pathology, EarlyView.Knowledge of the fungal genome and multifaceted evolutionary forces need to be considered together in understanding and managing agricultural plant pathogen adaptation relative to integrated disease management (IDM) strategies. ABSTRACT Crop production systems contribute significantly to maintaining global food security. These systems often involve the
Hayley Wilson +5 more
wiley +1 more source
A Method for Constructing Nucleosome Arrays with Spatially Defined Histone PTMs and DNA Damage
Angewandte Chemie, Volume 137, Issue 24, June 10, 2025.This work advances methodology by addressing challenges in mimicking the complex in vivo spatial relationships of histone acetylation and DNA damage. The combination of an abiotic/enzymatic hybrid catalyst system (ABEHCS) and the plug‐and‐play method has constituted a versatile platform to construct nucleosome arrays with precise histone acetylation ...
Ziyun Liu +6 more
wiley +2 more sources
Veterinary and Comparative Oncology, EarlyView.ABSTRACT One of the primary objectives of the Oncology Pathology Working Group (OPWG) is for oncologists and pathologists to collaboratively generate consensus documents to standardise aspects of and provide guidelines for oncologic pathology in veterinary species.
Michael O. Childress +14 more
wiley +1 more source
A Systematic Study of Nucleosome Core Particle and Nucleosome-Nucleosome Stacking Structure [PDF]
Biophysical Journal, 2018 Nikolay Korolev +2 more
openaire +2 more sources
Experimental Physiology, EarlyView.Abstract Circulating cell‐free DNA (cfDNA), circulating tumour DNA (ctDNA) and inflammatory cytokines have prognostic and predictive value in oncology. However, the effects of acute exercise on cfDNA levels are unknown. Here, we explore the kinetics of cfDNA, ctDNA and cytokines upon an incremental exercise test in a pilot cohort of cancer patients ...
Elmo W. I. Neuberger +10 more
wiley +1 more source
Management of T‐cell malignancies: Bench‐to‐bedside targeting of epigenetic biology
CA: A Cancer Journal for Clinicians, EarlyView.Abstract The peripheral T‐cell lymphomas (PTCL) are the only disease for which four histone deacetylase (HDAC) inhibitors have been approved globally as single agents. Although it is not clear why the PTCL exhibit such a vulnerability to these drugs, understanding the biological basis for this activity is essential.
Ariana Sabzevari +7 more
wiley +1 more source
Rapid Communications in Mass Spectrometry, Volume 39, Issue 14, 30 July 2025.ABSTRACT Rationale Edaravone (EDA) is a radical scavenger and an antioxidant drug approved to treat amyotrophic lateral sclerosis and used as a research tool to explore treatment of neurodegenerative diseases and cancers. It is also a reactive agent, known as PMP (1‐phenyl‐3‐methyl‐5‐pyrazolone), used for the analysis of polysaccharides composition ...
Romain Regnault +5 more
wiley +1 more source