Results 121 to 130 of about 72,215 (324)

Chromatin and nucleosome structure [PDF]

, 1976
Richard Mandel, Gerald D. Fasman
openalex   +1 more source

Nucleosomes Shape DNA Polymorphism and Divergence

PLoS Genetics, 2014
An estimated 80% of genomic DNA in eukaryotes is packaged as nucleosomes, which, together with the remaining interstitial linker regions, generate higher order chromatin structures [1].
Sasha A. Langley, G. Karpen, C. Langley
semanticscholar   +1 more source

Accurate and Efficient Detection of Nasopharyngeal Carcinoma Using Multi‐Dimensional Features of Plasma Cell‐Free DNA

Head &Neck, EarlyView.
ABSTRACT Background The incidence of Nasopharyngeal carcinoma (NPC) is rising in recent years, especially in some non‐developed parts of the world. Hence, cost‐efficient means for sensitive detection of NPC are vital. Methods We recruited 646 participants, including healthy individuals, patients with benign nasopharyngeal diseases, and NPC patients for
Song Zhang, Jiahui Tang, Pin Cui, Weihuang He, Xiaohui Lin, Shubing Wang, Yuanxian Liu, Xiaohua Tan, Shu Xu, Mingji Feng, Hanming Lai   +10 more
wiley   +1 more source

The nature of the interaction of nucleosomes with a eukaryotic RNA polymerase II [PDF]

, 1979
David M.J. Lilley, Melanie Jacobs, Michael Houghton   +2 more
openalex   +1 more source

A barrier nucleosome model for statistical positioning of nucleosomes throughout the yeast genome.

Genome Research, 2008
Most nucleosomes are well-organized at the 5' ends of S. cerevisiae genes where "-1" and "+1" nucleosomes bracket a nucleosome-free promoter region (NFR). How nucleosomal organization is specified by the genome is less clear.
Travis N. Mavrich, I. Ioshikhes, Bryan J. Venters, Cizhong Jiang, L. Tomsho, J. Qi, S. Schuster, I. Albert, B. Pugh   +8 more
semanticscholar   +1 more source

A hitchhiker's guide to single‐cell epigenomics: Methods and applications for cancer research

International Journal of Cancer, EarlyView.
Abstract Genetic mutations are well known to influence tumorigenesis, tumor progression, treatment response and relapse, but the role of epigenetic variation in cancer progression is still largely unexplored. The lack of epigenetic understanding in cancer evolution is in part due to the limited availability of methods to examine such a heterogeneous ...
Marta Moreno‐Gonzalez, Isabel Sierra, Jop Kind   +2 more
wiley   +1 more source

Chromatin Profiles of Chromosomally Integrated Human Herpesvirus-6A

Frontiers in Microbiology, 2019
Human herpesvirus-6A (HHV-6A) and 6B (HHV-6B) are two closely related betaherpesviruses that are associated with various diseases including seizures and encephalitis.
Anthony J. Saviola, Cosima Zimmermann, Michael P. Mariani, Sylvia A. Signorelli, Diana L. Gerrard, Joseph R. Boyd, Darren J. Wight, Guillaume Morissette, Annie Gravel, Isabelle Dubuc, Louis Flamand, Benedikt B. Kaufer, Seth Frietze   +12 more
doaj   +1 more source

Linking numbers and nucleosomes. [PDF]

, 1976
F H Crick
openalex   +1 more source

Phase separation directs ubiquitination of gene-body nucleosomes

Nature, 2020
Laura D. Gallego, Maren Schneider, Chitvan Mittal, Anete Romanauska, Ricardo M. Gudino Carrillo, Tobias Schubert, B. F. Pugh, A. Köhler   +7 more
semanticscholar   +1 more source

H3.3/H2A.Z double variant-containing nucleosomes mark ‘nucleosome-free regions’ of active promoters and other regulatory regions in the human genome

Nature Genetics, 2009
To understand how chromatin structure is organized by different histone variants, we have measured the genome-wide distribution of nucleosome core particles (NCPs) containing the histone variants H3.3 and H2A.Z in human cells.
C. Jin, C. Zang, Gang Wei, Kairong Cui, Weiqun Peng, K. Zhao, G. Felsenfeld   +6 more
semanticscholar   +1 more source