Results 151 to 160 of about 69,179 (216)

Nanoscale analysis of human G1 and metaphase chromatin in situ. [PDF]

EMBO J
Chen JK, Liu T, Cai S, Ruan W, Ng CT, Shi J, Surana U, Gan L.   +7 more
europepmc   +1 more source

Comprehensive analysis of multi‐omics single‐cell data using the single‐cell analyst

iMeta, Volume 4, Issue 3, June 2025.
Single‐cell analyst is a user‐friendly, web‐based platform designed for comprehensive multi‐omics single‐cell data analysis. Supporting six single‐cell omics types and spatial transcriptomics, it eliminates the need for coding, making advanced data analysis accessible to researchers of all expertize levels.
Lu Pan, Bufu Tang, Xuan Zhang, Paolo Parini, Roman Tremmel, Joseph Loscalzo, Volker M. Lauschke, Bradley A. Maron, Paola Paci, Ingemar Ernberg, Nguan Soon Tan, Ákos Végvári, Zehuan Liao, Sundararaman Rengarajan, Roman Zubarev, Yuxuan Fan, Xu Zheng, Xinyue Jian, Ren Sheng, Zhenning Wang, Xuexin Li   +20 more
wiley   +1 more source

Replication-dependent histone labeling dissects the physical properties of euchromatin/heterochromatin in living human cells. [PDF]

Sci Adv
Minami K, Nakazato K, Ide S, Kaizu K, Higashi K, Tamura S, Toyoda A, Takahashi K, Kurokawa K, Maeshima K.   +9 more
europepmc   +1 more source

Phase Separation: A New Dimension to Understanding Tumor Biology and Therapy

MedComm – Oncology, Volume 4, Issue 2, June 2025.
Liquid–liquid phase separation (LLPS) facilitates the assembly of biomolecular condensates by leveraging weak multivalent interactions. The low‐complexity domains, foldable domains of proteins, and nucleic acids provide multivalent interaction sites among different molecules and contribute to the formation of condensates.
Xingwen Wang, Minqiao Lu, Yi Zhang, Jiangwen Ma, Ying Hu   +4 more
wiley   +1 more source

The SUV39 Family of H3K9 Methyltransferases in Skeletal Muscle Stem Cells

FASEB BioAdvances, Volume 7, Issue 6, June 2025.
The SUV39 family members are well known for methylating the Lysine 9 of the histone H3 (H3K9) in order to compact the chromatin and contributing to gene repression. We describe their active role in proliferating and differentiating muscle stem cells, how they prevent from inflammation and fibrosis during muscle regeneration and the future avenues ...
Pauline Garcia, Slimane Ait‐Si‐Ali, Fabien Le Grand   +2 more
wiley   +1 more source

Circulating Nucleosomes and Histones in the Development of Lung Injury and Sepsis. [PDF]

Curr Issues Mol Biol
Dutta S, Dutta S, Somanath PR, Narayanan SP, Wang X, Zhang D.   +5 more
europepmc   +1 more source

Abstracts

Molecular Oncology, Volume 19, Issue S1, Page 1-895, June 2025.
Abstracts submitted to the ‘EACR 2025 Congress: Innovative Cancer Science’, from 16–19 June 2025 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley   +1 more source

Phosphorylation of an RNA‐Binding Protein Rck/Me31b by Hippo Is Essential for Adipose Tissue Aging

Aging Cell, Volume 24, Issue 6, June 2025.
Evolutionary conserved Hippo/Mst1 signaling non‐canonically regulates the stability of mRNAs through directly phosphorylating a subset of RNA binding proteins to stabilize lipolytic mRNAs. Hpo pathway contributes to the regulation of Drosophila lifespan by modulating the expression and activity of Me31b/RCK, which subsequently affects mRNA levels of ...
Eunbyul Yeom, Hyejin Mun, Jinhwan Lim, Yoo Lim Chun, Kyung‐Won Min, Johana Lambert, L. Ashley Cowart, Jason S. Pierce, Besim Ogretmen, Jung‐Hyun Cho, Jeong Ho Chang, J. Ross Buchan, Jason Pitt, Matt Kaeberlein, Sung‐Ung Kang, Eun‐Soo Kwon, Seungbeom Ko, Kyoung‐Min Choi, Yong Sun Lee, Yoon‐Su Ha, Seung‐Jin Kim, Kwang‐Pyo Lee, Hyo‐Sung Kim, Seo Young Yang, Chang Hoon Shin, Je‐Hyun Yoon, Kyu‐Sun Lee   +26 more
wiley   +1 more source

Nucleosome dynamics render heterochromatin accessible in living human cells. [PDF]

Nat Commun
Prajapati HK, Xu Z, Eriksson PR, Clark DJ.   +3 more
europepmc   +1 more source

Population Genomics Provides Insights Into Genomic Features of Inbreeding Depression in Arma Chinensis

Evolutionary Applications, Volume 18, Issue 6, June 2025.
ABSTRACT Arma chinensis, a predatory insect renowned for its prey diversity in East Asia, is effective in controlling agricultural and forestry pests. However, after introducing field populations into indoor subcultures, features of inbreeding depression have surfaced within these populations.
Bin Li, Kangkang Song, Zixian Wu, Xiaohua Zhang, Haozhen Li, Long Yang   +5 more
wiley   +1 more source