Results 151 to 160 of about 72,215 (324)
Association of DNA Polymerase with Nucleosomes from Mammalian Cell Chromatin [PDF]
, 1978 Ernst‐Jürgen Schlaeger +3 more
openalex +1 more source
Magnetic Resonance in Chemistry, EarlyView.The packing tools facilitate the handling of semisolid samples by enabling reproducible centrifugation‐based packing and controlled unloading into 3.2‐mm rotors used in cryogenic probes, thereby optimizing sample preparation for solid‐state NMR. ABSTRACT We present a compact, 3D‐printed device designed to facilitate the efficient packing of semisolid ...
Andrea Gelardo +1 more
wiley +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Outcomes for relapsed Ewing sarcoma remain consistently poor. Continued efforts to consider creative new approaches for the treatment of relapsed Ewing sarcoma are needed. The Children's Oncology Group Bone Tumor Committee convened a New Strategies for Ewing Sarcoma Task Force to systematically evaluate agents for inclusion in future Phase II ...
Jessica D. Daley +17 more
wiley +1 more source
Nucleosome structure studied with purified antibodies to histones H2B, H3 and H4 [PDF]
, 1978 D. R. Absolom, M.H.V. Van Regenmortel
openalex +1 more source
Key Regulators of Parasite Biology Viewed Through a Post‐Translational Modification Repertoire
PROTEOMICS, EarlyView.ABSTRACT Parasites are the leading causes of morbidity and mortality in both humans and animals, imposing substantial socioeconomic burdens worldwide. Controlling parasitic diseases has become one of the key issues in achieving “One Health”. Most parasites have sophisticated life cycles exhibiting progressive developmental stages, morphologies, and ...
Naiwen Zhang, Ning Jiang, Qijun Chen
wiley +1 more source
The isolation of nucleosomes from saline‐washed chromatin [PDF]
, 1976 L. Woodhead, E.W. Johns
openalex +1 more source
Small, EarlyView.Nano‐pulling induces stabilization, reorganization, and reorientation of the microtubule network. The nucleus of stretched cells experiences increased lateral tension, becomes more spherical, and develops surface grooves. At the level of gene expression regulation, changes in nuclear morphology induce global chromatin remodeling, leading to reduced ...
Alessandro Falconieri +7 more
wiley +1 more source
Supercoiling energy and nucleosome formation: the role of the arginine-rich histone kernel [PDF]
, 1977 R. Daniel Camerini‐Otero +1 more
openalex +1 more source
hTERT Increases TRF2 to Induce Telomere Compaction and Extend Cell Replicative Lifespan
Aging Cell, EarlyView.In contrast to the dogma that a subset of short telomeres initiates senescence, hTERT variants unable to maintain telomere length block senescence by stabilizing TRF2 via inhibiting upstream E3 ubiquitin ligases. This noncanonical hTERT function also compacts telomeres and blocks senescence‐associated DNA damage signaling. Cancer cells expressing hTERT
Nancy Adam +15 more
wiley +1 more source
Aging Cell, EarlyView.We performed the first integrative multiparametric analysis of plasma circulating cell‐free nucleic acids, including nuclear and mitochondrial DNA, as well as ribosomal, messenger, and micro‐RNAs, in a cohort of 139 healthy individuals. We focused on quantity, integrity, and DNA methylation using assays targeting highly repetitive DNA and highly ...
Nicolas P. Tessier +10 more
wiley +1 more source