Results 171 to 180 of about 109,383 (351)
Chemistry & Biology, 2010 In order to form a covalent complex with DNA inside human cells, cisplatin has to overcome the protective environment of a nucleosome, where DNA is complexed with histone proteins. Todd and Lippard (2010) expand our understanding of this process by describing the structure of a nucleosome containing a Pt-DNA adduct, which has important implications for
openaire +2 more sources
Optimized Cas‐SF01 gene‐editing toolbox shortens flowering timing in commercial maize inbred JING724
Journal of Integrative Plant Biology, EarlyView.The gene‐editing tool Cas‐SF01 was optimized to maximize its efficiency in maize. The Cas‐SF01‐TREX2 configuration was superior in enabling high‐purity gene mutations. This toolkit enabled commercial maize to flower seven days earlier without yield loss, thereby securing harvests and accelerating crop breeding.
Mengyuan Liu +11 more
wiley +1 more source
Pioneer transcription factors target partial DNA motifs on nucleosomes to initiate reprogramming.
Cell, 2015 A. Soufi +5 more
semanticscholar +1 more source
Epigenetic Regulation in the Pathogenesis of Periodontitis
Journal of Periodontal Research, EarlyView.The aim of this narrative literature review was to identify epigenetic marks associated with periodontitis and to place them in a biological context. The literature was reviewed based on pre‐defined criteria. Cell type specific chromatin and mRNA modifications were included.
Henrik Dommisch +3 more
wiley +1 more source
RNA inhibits dMi-2/CHD4 Chromatin Binding and Nucleosome Remodelling
, 2021 Ikram Ullah +14 more
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Single‐Cell CRISPR: An Efficient Strategy for Decoding Plant Cis‐Regulatory Complexity
Plant Biotechnology Journal, EarlyView.ABSTRACT The generation of complex traits involves the coordinated interplay of multiple gene networks. Elucidating the function of transcriptional cis‐regulatory elements (CREs) in regulating gene expression is crucial for understanding complex regulatory pathways and improving our ability to modify macro‐phenotypes.
Yuanhang Zhang +5 more
wiley +1 more source
H2B.W2, a Spermatocytes-specific Histone Variant, disrupts nucleosome stability and reduces chromatin compaction [PDF]
Thi Thuy Nguyen +11 more
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Histone Acetylation Status and DNA Sequence Modulate ATP-dependent Nucleosome Repositioning [PDF]
, 2002 Władysław Krajewski
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