Results 151 to 160 of about 10,982 (239)
Enhanced DNA repair synthesis in hyperacetylated nucleosomes
We have investigated the level of 'early' DNA repair synthesis in nucleosome subpopulations, varying in histone acetylation, from normal human fibroblasts treated with sodium butyrate. We find that repair synthesis occurring during the first 30 min after
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Tissue Resident Memory Cells: Friend or Foe?
Immunology, EarlyView.Tissue‐resident memory T cells (TRM cells) are specialised immune cells in barrier tissues like the lungs, skin and gut, providing rapid host defence and tumour surveillance. Their retention and differentiation are regulated by molecules such as CD69, CD103 and TGF‐β. Dysregulation of TRM cells can lead to chronic activation, driving conditions such as
Chidimma F. Chude +2 more
wiley +1 more source
Journal of Integrative Plant Biology, EarlyView.This review decodes the grammar of plant cis‐regulatory elements, revealing that their function emerges from sequence, chromatin accessibility, 3D topology, and cell type context. It highlights how single‐cell omics, CRISPR dissection, and AI‐driven design converge to enable predictive engineering and crop improvement. ABSTRACT Cis‐regulatory elements (
Libin Zhang, Maoteng Li
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A Systematic Study of Nucleosome Core Particle and Nucleosome-Nucleosome Stacking Structure [PDF]
Biophysical Journal, 2018 Nikolay Korolev +2 more
openaire +1 more source
Transcription of nucleosomes from human chromatin
, 1978 Nucleosomes (chromatin subunits) prepared by micrococcal nuclease diges-tion of human nuclei are similar in histone content but substantially reduced in non-histone proteins as compared to undigested chromatin.
Grady F. Saunders +3 more
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Journal of Microscopy, EarlyView.Abstract Since its introduction 40 years ago, atomic force microscopy (AFM) has transformed nanoscale imaging across the physical and life sciences. In biology, AFM has provided unprecedented insights into nanoscale biomolecular organisation under near‐physiological conditions, revealing structures and interactions inaccessible to many conventional ...
Yueqi Wang +5 more
wiley +1 more source
Journal of Anatomy, EarlyView.A well‐preserved 20 post‐conception week human brain was obtained and finely dissected into 18 anatomically distinct regions, including the pia mater. Each region underwent in‐depth proteomic analysis, encompassing both total protein content and post‐translational modifications.
S. Bandiera +9 more
wiley +1 more source
Epigenetic Regulation in the Pathogenesis of Periodontitis
Journal of Periodontal Research, EarlyView.The aim of this narrative literature review was to identify epigenetic marks associated with periodontitis and to place them in a biological context. The literature was reviewed based on pre‐defined criteria. Cell type specific chromatin and mRNA modifications were included.
Henrik Dommisch +3 more
wiley +1 more source
New Phytologist, EarlyView.Single‐nucleus transcriptome profiles of Heterodera schachtii–induced syncytium on Arabidopsis roots. Summary Plant‐parasitic cyst nematodes induce the formation of specialized feeding structures, known as syncytia, within host roots by orchestrating extensive transcriptional and epigenetic reprogramming.
Tarek Hewezi +5 more
wiley +1 more source