The FEBS Journal, EarlyView.Under normoxic conditions, the SUMOylated fraction of TFAP2A cannot interact with the Ku70/Ku80 complex, nor it can bind to chromatin. The unSUMOylated fraction pre‐occupies the chromatin of a subset of hypoxia‐induced genes together with the Ku70/Ku80 complex for basal euchromatin formation. Under hypoxic conditions, the SUMOylation equilibrium shifts
Amalia Kanoura +8 more
wiley +1 more source
Histone packing in the nucleosome core particle of chromatin
, 1978 C. W. Carter
openalex +1 more source
Escherichia coli single-strand binding protein organizes single-stranded DNA in nucleosome-like units. [PDF]
, 1982 Susan A. Chrysogelos, Jack D. Griffith
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Transcription‐coupled repair: tangled up in convoluted repair
The FEBS Journal, EarlyView.In this review, we discuss recent findings derived from diverse genomic, biochemical and structural, imaging, and functional studies (B–E) that culminated in deep mechanistic insight (A) into the vital cellular process of transcription‐coupled nucleotide excision repair (TC‐NER).
Diana A. Llerena Schiffmacher +3 more
wiley +1 more source
Distribution of linker DNA in relation to core DNA in H1 depleted nucleosomes [PDF]
, 1981 Jean‐Jacques Lawrence +1 more
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Neocortical neurogenesis: a proneural gene perspective
The FEBS Journal, EarlyView.The neocortex is a mammalian‐specific brain region responsible for higher‐order cognitive functioning that shares fundamental similarities across species, but which is larger and more complex in humans. Proneural genes, encoding basic helix–loop–helix transcription factors (TFs), are evolutionarily conserved drivers of neurogenesis from fly to human ...
Lakshmy Vasan +3 more
wiley +1 more source
A Systematic Study of Nucleosome Core Particle and Nucleosome-Nucleosome Stacking Structure [PDF]
Biophysical Journal, 2018 Nikolay Korolev +2 more
openaire +2 more sources
Chromatin folding by the Polycomb group proteins and its elusive role in epigenetic repression
The FEBS Journal, EarlyView.Genes repressed by the Polycomb system display greater chromatin folding compared to ‘regular’ inactive genes. The associated chromatin compaction, driven by PRC1‐H3K27me3 interactions, is modest and dynamic. This questions traditional models where Polycomb proteins repress transcription by sheltering genes from transcriptional activators.
Ludvig Lizana, Yuri B. Schwartz
wiley +1 more source
Melbournevirus encodes a shorter H2B-H2A doublet histone variant that forms structurally distinct nucleosome structures. [PDF]
Nat CommunVillalta A +4 more
europepmc +1 more source
The dependence of the linking number of a circular minichromosome upon the shape and the orientation of its nucleosomes [PDF]
, 1981 Sergei A. Grigoryev, L. B. Ioffe
openalex +1 more source