Nucleosome—nucleosome interaction in chromatin
FEBS Letters, 1979 The available data suggest that transcriptional activity of chromatin is connected with its structural changes [ 1,2]. According to the electron microscope evidence, the elementary 100 A chromatin thread can exist in two main states, i.e., in a compact state, which is characterized by tight packing of nucleosomes and in an extended state when the ...
S. B. Svetlikova +2 more
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Science Advances, 2015 Reestablishment of the nucleosome landscape behind the replication fork is fundamental for epigenetic memory during development.
Ramachandran, Srinivas, Henikoff, Steven
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Conserved substitution patterns around nucleosome footprints in eukaryotes and Archaea derive from frequent nucleosome repositioning through evolution. [PDF]
, 2013 Nucleosomes, the basic repeat units of eukaryotic chromatin, have been suggested to influence the evolution of eukaryotic genomes, both by altering the propensity of DNA to mutate and by selection acting to maintain or exclude nucleosomes in particular ...
Becker, Erin +4 more
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Nucleosomes indicate the in vitro radiosensitivity of irradiated bronchoepithelial and lung cancer cells [PDF]
, 2004 Nucleosomes, which are typical cell death products, are elevated in the serum of cancer patients and are known to rapidly increase during radiotherapy.
Al-Batran SE +14 more
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Evaluation of nucleosome forming potentials (NFPs) of forensically important STRs [PDF]
, 2011 Degraded forensic samples have proved difficult to analyze and interpret. New analysis techniques are constantly being discovered and improved but researchers have overlooked the structural properties that could prevent or slow the process of degradation.
Thanakiatkrai, Phuvadol, Welch, Lindsey
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Quantitative test of the barrier nucleosome model for statistical positioning of nucleosomes up- and downstream of transcription start sites [PDF]
, 2010 The positions of nucleosomes in eukaryotic genomes determine which parts of the DNA sequence are readily accessible for regulatory proteins and which are not.
A Flaus +46 more
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Histone modifications influence the action of Snf2 family remodelling enzymes by different mechanisms [PDF]
, 2007 Alteration of chromatin structure by chromatin modifying and remodelling activities is a key stage in the regulation of many nuclear processes. These activities are frequently interlinked, and many chromatin remodelling enzymes contain motifs that ...
Ferreira, Helder +2 more
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Mediator–Nucleosome Interaction [PDF]
Molecular Cell, 2000 Mediator, a multiprotein complex involved in the regulation of RNA polymerase II transcription, binds to nucleosomes and acetylates histones. Three lines of evidence identify the Nut1 subunit of Mediator as responsible for the histone acetyltransferase (HAT) activity. An "in-gel" HAT assay reveals a single band of the appropriate size.
Lawrence C. Myers +4 more
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Nucleosomes in colorectal cancer patients during radiochemotherapy [PDF]
, 2006 Apoptotic markers and tumor-associated antigens might be suitable to indicate the response to radiochemotherapy early. We analyzed the courses of nucleosomes, CEA, CA 19-9 and CYFRA 21-1 in 25 colorectal cancer patients during radiochemotherapy (4 ...
Andreas Kremer +19 more
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PuFFIN--a parameter-free method to build nucleosome maps from paired-end reads. [PDF]
, 2014 BackgroundWe introduce a novel method, called PuFFIN, that takes advantage of paired-end short reads to build genome-wide nucleosome maps with larger numbers of detected nucleosomes and higher accuracy than existing tools. In contrast to other approaches
Bunnik, Evelien M +3 more
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