Results 31 to 40 of about 10,982 (239)
Nucleosome—nucleosome interaction in chromatin
FEBS Letters, 1979 The available data suggest that transcriptional activity of chromatin is connected with its structural changes [ 1,2]. According to the electron microscope evidence, the elementary 100 A chromatin thread can exist in two main states, i.e., in a compact state, which is characterized by tight packing of nucleosomes and in an extended state when the ...
Pospelov, V.A. +2 more
openaire +2 more sources
Nucleosomes indicate the in vitro radiosensitivity of irradiated bronchoepithelial and lung cancer cells [PDF]
, 2004 Nucleosomes, which are typical cell death products, are elevated in the serum of cancer patients and are known to rapidly increase during radiotherapy.
Mitlewski, Anke +7 more
core +1 more source
The Role of Histone Variants in the Epithelial-To-Mesenchymal Transition
Cells, 2020 The epithelial-to-mesenchymal transition (EMT) is a physiological process activated during early embryogenesis, which continues to shape tissues and organs later on. It is also hijacked by tumor cells during metastasis. The regulation of EMT has been the
Imtiaz Nisar Lone +4 more
doaj +1 more source
Nucleosomes in serum as a marker for cell death [PDF]
, 2001 The concentration of nucleosomes is elevated in blood of patients with diseases which are associated with enhanced cell death. In order to detect these circulating nucleosomes, we used the Cell Death Detection-ELISA(Plus) (CDDE) from Roche Diagnostics ...
Holdenrieder, Stefan +15 more
core +1 more source
Transcription Factor NF-κB Unravels Nucleosomes [PDF]
, 2021 NF-κB is a transcription factor responsible for activating hundreds of genes in mammalian organisms. To accomplish its function, NF-κB must interact with DNA occupied by nucleosomes, but how this interaction occurs is unclear.
Filliaux, Shaun +12 more
core +1 more source
Probing the (H3-H4)(2) histone tetramer structure using pulsed EPR spectroscopy combined with site-directed spin labelling [PDF]
, 2009 The (H3-H4)(2) histone tetramer forms the central core of nucleosomes and, as such, plays a prominent role in assembly, disassembly and positioning of nucleosomes.
Ward, Richard +7 more
core +1 more source
Dissociation rate compensation mechanism for budding yeast pioneer transcription factors
eLife, 2019 Nucleosomes restrict the occupancy of most transcription factors (TF) by reducing binding and accelerating dissociation, while a small group of TFs have high affinities to nucleosome-embedded sites and facilitate nucleosome displacement.
Benjamin T Donovan +4 more
doaj +1 more source
TRF2 controls telomeric nucleosome organization in a cell cycle phase-dependent manner [PDF]
, 2012 Mammalian telomeres stabilize chromosome ends as a result of their assembly into a peculiar form of chromatin comprising a complex of non-histone proteins named shelterin.
Giraud-Panis, Marie-Josèphe +45 more
core +2 more sources
Biomolecules, 2022 Background: Neutrophil extracellular traps’ (NETs’) formation is a mechanism of defense that neutrophils deploy as an alternative to phagocytosis, to constrain the spread of microorganisms.
Laure Morimont +14 more
doaj +1 more source
CENP-A confers a reduction in height on octameric nucleosomes [PDF]
, 2013 Nucleosomes with histone H3 replaced by CENP-A direct kinetochore assembly. CENP-A nucleosomes from human and Drosophila have been reported to have reduced heights as compared to canonical octameric H3 nucleosomes, thus suggesting a unique tetrameric ...
Colin J Fuller +26 more
core +1 more source