Results 31 to 40 of about 109,383 (351)
Reciprocal intronic and exonic histone modification regions in humans. [PDF]
, 2010 While much attention has been focused on chromatin at promoters and exons, human genes are mostly composed of intronic sequences. Analyzing published surveys of nucleosomes and 41 chromatin marks in humans, we identified histone modifications ...
Guthrie, Christine +3 more
core +5 more sources
Interaction of the pioneer transcription factor GATA3 with nucleosomes
Nature Communications, 2020 During cellular reprogramming, the pioneer transcription factor GATA3 binds chromatin, and in a context-dependent manner directs local chromatin remodeling and enhancer formation.
Hiroki Tanaka +7 more
semanticscholar +1 more source
Physical Review Letters, 2008 We present a statistical-mechanical model for the positioning of nucleosomes along genomic DNA molecules as a function of the strength of the binding potential and the chemical potential of the nucleosomes. We show that a significant section of the DNA is composed of two-level nucleosome switching regions where the nucleosome distribution undergoes a ...
David J, Schwab +3 more
openaire +2 more sources
Inter-nucleosomal potentials from nucleosomal positioning data
The European Physical Journal E, 2022 AbstractNo systematic method exists to derive inter-nucleosomal potentials between nucleosomes along a chromosome consistently across a given genome. Such potentials can yield information on nucleosomal ordering, thermal as well as mechanical properties of chromosomes.
Kunhe Li +3 more
openaire +2 more sources
Centromere-Specific Assembly of CENP-A Nucleosomes Is Mediated by HJURP
Cell, 2009 Daniel R Foltz +2 more
exaly +2 more sources
Scientific Reports, 2020 The nucleosome is the basic structural repeating unit of chromatin. DNA damage and cell apoptosis release nucleosomes into the blood circulatory system, and increased levels of circulating nucleosomes have been observed to be related to inflammation and ...
Huawei Wang +9 more
doaj +1 more source
A species-specific nucleosomal signature defines a periodic distribution of amino acids in proteins [PDF]
Open Biology, 2015 Nucleosomes are the basic structural units of chromatin. Most of the yeast genome is organized in a pattern of positioned nucleosomes that is stably maintained under a wide range of physiological conditions.
Luis Quintales +4 more
doaj +1 more source
Analysis of nucleosome repositioning by yeast ISWI and Chd1 chromatin remodeling complexes [PDF]
, 2006 ISWI proteins form the catalytic core of a subset of ATP-dependent chromatin remodelling activities in eukaryotes from yeast to man. Many of these complexes have been found to reposition nucleosomes, but with different directionalities.
Alen +33 more
core +4 more sources
Nucleosome Positioning, Nucleosome Spacing and the Nucleosome Code [PDF]
Journal of Biomolecular Structure and Dynamics, 2010 Nucleosome positioning has been the subject of intense study for many years. The properties of micrococcal nuclease, the enzyme central to these studies, are discussed. The various methods used to determine nucleosome positions in vitro and in vivo are reviewed critically.
openaire +2 more sources
EXTRACELLULAR DNA AND THE LEVEL OF ITS METHYLATION IN DIFFERENT RHEUMATIC DISEASES
Научно-практическая ревматология, 2012 Objective: to study the qualitative and quantitative composition of serum extracellular DNA (exDNA); apoptotic (nucleosomes) and necrotic fragmentation; complexification of monometinic proteins with exDNA; and the levels of exDNA methylation as compared ...
N O Shubayeva +4 more
doaj +1 more source