Relaxin-3 Innervation From the Nucleus Incertus to the Parahippocampal Cortex of the Rat [PDF]
Frontiers in Neuroanatomy, 2021 Spatial learning and memory processes depend on anatomical and functional interactions between the hippocampus and the entorhinal cortex. A key neurophysiological component of these processes is hippocampal theta rhythm, which can be driven from ...
Cristina García-Díaz +10 more
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Control of locomotor speed, arousal, and hippocampal theta rhythms by the nucleus incertus [PDF]
Nature Communications, 2020 In addition to activation of locomotor circuits, navigation also requires regulation of arousal and spatial memory processes. Here the authors identify neuromedin B neurons in the nucleus incertus and their subcortical projections in controlling these ...
Lihui Lu +11 more
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Genetically defined nucleus incertus neurons differ in connectivity and function [PDF]
eLife, 2022 The nucleus incertus (NI), a conserved hindbrain structure implicated in the stress response, arousal, and memory, is a major site for production of the neuropeptide relaxin-3.
Emma D Spikol +4 more
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Involvement of the Nucleus Incertus and Relaxin-3/RXFP3 Signaling System in Explicit and Implicit Memory [PDF]
Frontiers in Neuroanatomy, 2021 Telencephalic cognitive and emotional circuits/functions are strongly modulated by subcortical inputs. The main focus of past research on the nature of this modulation has been on the widespread monoamine projections to the telencephalon.
Isis Gil-Miravet +8 more
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Functional Neuroanatomy of the Rat Nucleus Incertus–Medial Septum Tract: Implications for the Cell-Specific Control of the Septohippocampal Pathway [PDF]
Frontiers in Cellular Neuroscience, 2022 The medial septum (MS) is critically involved in theta rhythmogenesis and control of the hippocampal network, with which it is reciprocally connected. MS activity is influenced by brainstem structures, including the stress-sensitive, nucleus incertus (NI)
Agata Szlaga +11 more
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Nucleus incertus provides eye velocity and position signals to the vestibulo-ocular cerebellum: a new perspective of the brainstem–cerebellum–hippocampus network [PDF]
Frontiers in Systems Neuroscience, 2023 The network formed by the brainstem, cerebellum, and hippocampus occupies a central position to achieve navigation. Multiple physiological functions are implicated in this complex behavior.
Guy Cheron +7 more
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Fear memory recall involves hippocampal somatostatin interneurons. [PDF]
PLoS Biology, 2023 Fear-related memory traces are encoded by sparse populations of hippocampal principal neurons that are recruited based on their inhibitory-excitatory balance during memory formation.
Krisztián Zichó +8 more
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Relaxin ligand/receptor systems in the developing teleost fish brain: Conserved features with mammals and a platform to address neuropeptide system functions [PDF]
Frontiers in Molecular Neuroscience, 2022 The relaxins (RLNs) are a group of peptide hormone/neuromodulators that can regulate a wide range of physiological processes ranging from reproduction to brain function.
Anna Blasiak +6 more
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Involvement of the orexin 1 and 2 receptors in nucleus incertus (NI) on modulation of spatial reference memory in the Morris water maze [PDF]
Archives of Razi InstituteThe nucleus incertus (NI) is a distinct area within the brainstem near the posterior part of the tegmentum. This part of the brain consists of some heterogeneous neurons that play roles in different functions, including response to stress, arousal ...
Fatemeh Eslamisaravi +3 more
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Targeted viral vector transduction of relaxin-3 neurons in the rat nucleus incertus using a novel cell-type specific promoter [PDF]
IBRO Reports, 2020 Modern neuroscience utilizes transgenic techniques extensively to study the activity and function of brain neural networks. A key feature of this approach is its compatibility with molecular methods for selective transgene expression in neuronal circuits
Alexander D. Wykes +3 more
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