Results 121 to 130 of about 37,468 (260)

Advancements in Mass Spectrometry‐Based Glycomics in Food and Nutritional Science

Mass Spectrometry Reviews, EarlyView.
ABSTRACT This review highlights advancements in mass spectrometry (MS)‐based glycomics in food and nutritional science. Carbohydrates, which are vital for human health, exhibit complex structures, making their analysis challenging. MS has become an indispensable tool for elucidating the structures of carbohydrates, including glycans, through soft ...
JaeHui Song, HyunJi Lee, Youngshik Choe, Hyeyoung Lee   +3 more
wiley   +1 more source

Deciphering the functions of O-GlcNAc glycosylation in the brain: The role of site-specific quantitative O-GlcNAcomics [PDF]

, 2018
The dynamic posttranslational modification O-linked β-N-acetylglucosamine glycosylation (O-GlcNAcylation) is present on thousands of intracellular proteins in the brain.
Hsieh-Wilson, Linda C., Sorum, Alexander W., Thompson, John W.   +2 more
core  

The O-GlcNAc Transferase Intellectual Disability Mutation L254F Distorts the TPR Helix [PDF]

, 2018
O-linked β-N-acetyl-D-glucosamine (O-GlcNAc) transferase (OGT) regulates protein O-GlcNAcylation, an essential post-translational modification that is abundant in the brain.
Abraham, Battye, Berendsen, Borodkin, Bouazzi, Bussi, Cole, Connarn, Darden, Deplus, Feenstra, Francisco, Gorrec, Hess, Iyer, Joung, Jínek, Kappel, Kochinke, Lamb, Lazarus, Lindorff-Larsen, Lubas, McGibbon, Michaud-Agrawal, Miyamoto, März, Niranjan, Okuyama, Pathak, Pekkurnaz, Rafie, Ropers, Scheufler, Timbers, Vagin, Vaidyanathan, Willems, Winn, Yang, Yang, Zeytuni   +41 more
core   +2 more sources

Direct interaction between MreB and the RodA‐PBP2 complex organizes lateral cell wall synthesis in Escherichia coli

mLife, EarlyView.
Abstract The elongasome, or the Rod complex, orchestrates lateral peptidoglycan (PG) synthesis in many rod‐shaped bacteria. It consists of the actin‐like protein MreB, the PG synthase RodA‐PBP2 complex, as well as MreCD and RodZ. Although the loss or disruption of any elongasome component results in a loss of rod shape, previous studies found that a ...
Rui Zhan, Han Gong, Ying Li, Xiangdong Chen, Joe Lutkenhaus, Shishen Du   +5 more
wiley   +1 more source

The Chemical Neurobiology of Carbohydrates [PDF]

, 2008
The cell surface displays a complex array of oligosaccharides, glycoproteins, and glycolipids. This diverse mixture of glycans contains a wealth of information, modulating a wide range of processes such as cell migration, proliferation, transcriptional ...
Hsieh-Wilson, Linda C., Murrey, Heather E.   +1 more
core   +1 more source

The N‐Glycome to Differentiate Mesenchymal Stem Cells Upon Chondrogenic Differentiation, Dedifferentiation, and Senescence

PROTEOMICS, EarlyView.
ABSTRACT Mesenchymal stem cells (MSCs) are adult stem cells able to self‐renewal or differentiation into different cell types, including chondrocytes. N‐Glycans are post‐translational modifications of glycoproteins that contribute to vital cell functions.
Houda Montacir, Karina Biskup, Michael Sittinger, Rudolf Tauber, Véronique Blanchard   +4 more
wiley   +1 more source

Oct-2 DNA binding transcription factor: functional consequences of phosphorylation and glycosylation [PDF]

, 2017
Phosphorylation and O-GlcNAc modification often induce conformational changes and allow the protein to specifically interact with other proteins. Interplay of phosphorylation and O-GlcNAc modification at the same conserved site may result in the protein ...
Ahmad, Ishtiaq, Hoessli, Daniel C., Nasir-ud-Din,,, Rafik, Saleem M., Shakoori, Abdul R., Walker-Nasir, Evelyne   +5 more
core  

GALNT2 as a novel modulator of adipogenesis and adipocyte insulin signaling [PDF]

, 2019
Background/objectives: A better understanding of adipose tissue biology is crucial to tackle insulin resistance and eventually coronary heart disease and diabetes, leading causes of morbidity and mortality worldwide.
Antonucci, A., De Bonis, Maria Caterina, Di Paola, R., Mangiacotti, D., Marucci, A., Scarale, M. G., Trischitta, V.   +6 more
core   +1 more source

Comparison of Three Sympatric Desert Lizards: Digestive Tract Structure, Digestive Enzyme Activities, Gut Microbiota, and Metabolites

Integrative Zoology, EarlyView.
We performed 16S rDNA sequencing and metabolite profiling for three sympatric lizard species—Teratoscincus roborowskii, Phrynocephalus axillaris, and Eremias roborowskii—and compared their goblet cell and enzyme activities in the digestive tract. Our study suggests that the dietary niche may promote divergence or convergence of microbiota across host ...
Yi Yang, Ziyi Wang, Ruichen Wu
wiley   +1 more source

Catalytic deficiency of O-GlcNAc transferase leads to X-linked intellectual disability [PDF]

, 2019
O-GlcNAc transferase (OGT) is an X-linked gene product that is essential for normal development of the vertebrate embryo. It catalyses the O-GlcNAc posttranslational modification of nucleocytoplasmic proteins and proteolytic maturation of the ...
Allen, Andrew T. Ferenbach, Ariane C. Wilmes, Daan M. F. van Aalten, Dai, Das, Fourneau, Gundogdu, Han, Hwang, Koufaris, Marios P. Stavridis, Mehmet Gundogdu, Miura, Neri, Peng, Poonam S. Kakade, Shelagh Joss, Stevenson, Sui, Vasudha Vandadi, Veronica M. Pravata, Villo Muha, Vladimir S. Borodkin   +23 more
core   +2 more sources