Results 141 to 150 of about 4,448 (184)

O-GlcNAcase promotes dendritic spine morphogenesis while downregulating their GluA2-containing AMPA receptors. [PDF]

J Biol Chem
Han L, Galizia S, Pan J, Bhattacharjee M, Lagerlöf O.   +4 more
europepmc   +1 more source

Intellectual disability and neurogenesis defects associated with increased turnover of an O-GlcNAcase variant

, 2023
Authier F, Attianese B, Bartual SG, Mitchell CW, Ferenbach AT, Doummar D, Charles P, Mignot C, Keren B, van Aalten DMF.   +9 more
europepmc   +1 more source

Extracellular Vesicle-Mediated O-GlcNAcase Transfer Drives Neuronal Necroptosis to Facilitate Gallbladder Cancer Perineural Invasion. [PDF]

Cancer Res
Zhao J, Zhu J, Yang Z, Zhai Y, Zhao C, Lu Z, Shen D, Tang Q, Song X, Jiang L, Dai W, Wang Y, Zhu Y, Shi L, Bao R, Geng Z, Wang Z, Liu S, Gong W.   +18 more
europepmc   +1 more source

Radiosynthesis and evaluation of a carbon-11 labeled PET ligand for imaging of O-GlcNAcase. [PDF]

Am J Nucl Med Mol Imaging
Li Y, Zhou X, Song Z, Zhao T, Rong J, Chen J, Zhao C, Hu Q, Li X, Li C, Sun Z, Gao Y, Patel JS, Chaudhary A, Yuan H, Liang SH.   +15 more
europepmc   +1 more source

Involvement of NDPK-B in Glucose Metabolism-Mediated Endothelial Damage via Activation of the Hexosamine Biosynthesis Pathway and Suppression of O-GlcNAcase Activity. [PDF]

Cells, 2020
Chatterjee A, Eshwaran R, Poschet G, Lomada S, Halawa M, Wilhelm K, Schmidt M, Hammes HP, Wieland T, Feng Y.   +9 more
europepmc   +1 more source

Erratum: “Isoforms of Human O-GlcNAcase Show Distinct Catalytic Efficiencies” [PDF]

Biochemistry (Moscow), 2010
Jing Li, Cai-luan Huang, Lian-wen Zhang, Lin Lin, Zhong-hua Li, Fu-wu Zhang, Peng Wang   +6 more
openaire   +1 more source

In vivo quantification of [¹¹C]BIO-1819578 in non-human primates, a novel radioligand for O-GlcNAcase. [PDF]

J Cereb Blood Flow Metab
Bolin M, Nag S, Arakawa R, Varrone A, Farde L, Martarello L, Kaliszczak MA, Halldin C, Morén AF.   +8 more
europepmc   +1 more source

Modification of the Thioglycosyl-Naphthalimides as Potent and Selective Human O-GlcNAcase Inhibitors. [PDF]

ACS Med Chem Lett, 2018
Shen S, Dong L, Chen W, Zeng X, Lu H, Yang Q, Zhang J.   +6 more
europepmc   +1 more source

Development of chemical tools for studying human O-GlcNAcase activity

, 2015
In recent years, the post-translational modification of nuclear and cytoplasmic proteins with O-linked N-acetylglucosamine (O-GlcNAc) has emerged as playing diverse roles in health and disease. Interestingly, this modification is regulated by only two enzymes, O-GlcNAc transferase (OGT) and O-GlcNAcase (OGA).
openaire   +1 more source

O-GlcNAcase Is an RNA Polymerase II Elongation Factor Coupled to Pausing Factors SPT5 and TIF1β. [PDF]

J Biol Chem, 2016
Resto M, Kim BH, Fernandez AG, Abraham BJ, Zhao K, Lewis BA.   +5 more
europepmc   +1 more source