Results 141 to 150 of about 6,789 (241)

Obeticholic Acid Protects against Gestational Cholestasis-Induced Fetal Intrauterine Growth Restriction in Mice [PDF]

, 2019
Wei Chen, Xingxing Gao, Li Ma, Zhibing Liu, Li Li, Hua Wang, Lan Gao, De‐Xiang Xu, Yuan‐Hua Chen   +8 more
openalex   +1 more source

Cholecystectomy-related gut microbiota dysbiosis exacerbates colorectal tumorigenesis

Nature Communications
Cholecystectomy represents the most prevalent biliary surgical procedure for gallbladder abnormalities. Growing evidence suggests that cholecystectomy is associated with an elevated risk of colorectal cancer.
Bo Tang, Shengpeng Li, Xin Li, Jialin He, An Zhou, Lingyi Wu, Xu Xiao, Sumin Wang, Hongfei Jiang, Jincheng Jian, Zhanjie Hou, Yusong Ge, Yuanyuan Lei, Jianchun Zhou, Dianji Tu, Cheng Lu, Min Yang, Shiming Yang   +17 more
doaj   +1 more source

Post-translational modifications of lipid-activated nuclear receptors: Focus on metabolism [PDF]

, 2017
Post-translational modifications (PTM) occur to nearly all proteins, are catalysed by specific enzymes and are subjected to tight regulation. They have been shown to be a powerful means by which the function of proteins can be modified resulting in ...
Becares Salles, N, Gage, MC, Pineda-Torra, I   +2 more
core  

Safety and tolerability of obeticholic acid in chronic liver disease: a pooled analysis of 1878 individuals. [PDF]

Hepatol Commun, 2023
Ng CH, Tang ASP, Xiao J, Wong ZY, Yong JN, Fu CE, Zeng RW, Tan C, Wong GHZ, Teng M, Chee D, Tan DJH, Chan KE, Huang DQ, Chew NWS, Nah B, Siddqui MS, Sanyal AJ, Noureddin M, Muthiah M.   +19 more
europepmc   +1 more source

PTH-107 A Preliminary Study Of The Effects Of Obeticholic Acid, A Farnesoid X Receptor Agonist, In Patients With Chronic Diarrhoea Secondary To Crohn’s Ileal Disease [PDF]

, 2014
JD Nolan, Claire Vassie, IM Johnston, Д. А. Шапиро, Julian R.F. Walters   +4 more
openalex   +1 more source

A perspective study of the possible impact of obeticholic acid against SARS-CoV-2 infection. [PDF]

Inflammopharmacology, 2023
Batiha GE, Al-Kuraishy HM, Al-Gareeb AI, Youssef FS, El-Sherbeni SA, Negm WA.   +5 more
europepmc   +1 more source

Anti-Cholestatic Therapy with Obeticholic Acid Improves Short-Term Memory in Bile Duct-Ligated Mice. [PDF]

Am J Pathol, 2023
Gee LMV, Barron-Millar B, Leslie J, Richardson C, Zaki MYW, Luli S, Burgoyne RA, Cameron RIT, Smith GR, Brain JG, Innes B, Jopson L, Dyson JK, McKay KRC, Pechlivanis A, Holmes E, Berlinguer-Palmini R, Victorelli S, Mells GF, Sandford RN, Palmer J, Kirby JA, Kiourtis C, Mokochinski J, Hall Z, Bird TG, Borthwick LA, Morris CM, Hanson PS, Jurk D, Stoll EA, LeBeau FEN, Jones DEJ, Oakley F.   +33 more
europepmc   +1 more source

Predictors of serious adverse events and non-response in cirrhotic patients with primary biliary cholangitis treated with obeticholic acid. [PDF]

Liver Int, 2022
De Vincentis A, D'Amato D, Cristoferi L, Gerussi A, Malinverno F, Lleo A, Colapietro F, Marra F, Galli A, Fiorini C, Coco B, Brunetto M, Niro GA, Cotugno R, Saitta C, Cozzolongo R, Losito F, Giannini EG, Labanca S, Marzioni M, Marconi G, Morgando A, Pellicano R, Vanni E, Cazzagon N, Floreani A, Chessa L, Morelli O, Muratori L, Pellicelli A, Pompili M, Ponziani F, Tortora A, Rosina F, Russello M, Cannavò M, Simone L, Storato S, Viganò M, Abenavoli L, D'Antò M, De Gasperi E, Distefano M, Scifo G, Zolfino T, Calvaruso V, Cuccorese G, Palitti VP, Sacco R, Bertino G, Frazzetto E, Alvaro D, Mulinacci G, Palermo A, Scaravaglio M, Terracciani F, Galati G, Ronca V, Zuin M, Claar E, Izzi A, Picardi A, Invernizzi P, Vespasiani-Gentilucci U, Carbone M, on behalf of the Club Epatologi Ospedalieri (CLEO)/Associazione Italiana Gastroenterologi ed Endoscopisti Digestivi Ospedalieri (AIGO) PBC Study Group and, the Italian PBC Registry.   +66 more
europepmc   +1 more source

Metabolic Profile of Obeticholic Acid and Endogenous Bile Acids in Rats with Decompensated Liver Cirrhosis

, 2017
Aldo Roda, Rita Aldini, Cecilia Camborata, Silvia Spinozzi, Placido Franco, Massimiliano Cont, Antonietta D’Errico, Francesco Vasuri, Alessio Degiovanni, Lorenzo Maroni, Luciano Adorini   +10 more
openalex   +1 more source

Pharmaco-nutraceutical improvement of the response to obeticholic acid with omega-3 polyunsaturated fatty acids. [PDF]

Biochem J
Lavoie AA, Thérien A, Silva A, Paré E, Ciešlak A, Gagnon W, Desjardins C, Verreault M, Trottier J, Vohl MC, Drouin-Chartier JP, Corbeil J, Caron A, Barbier O.   +13 more
europepmc   +1 more source