Results 91 to 100 of about 678 (141)

Isatin-pyridine oxime hybrids as potential reactivators of A-242-inhibited acetylcholinesterase. [PDF]

Arch Toxicol
Pinto AMV, Bhattacharyya D, da Silva MCJ, Kitagawa DAS, Dos Santos MC, Cavalcante SFA, Islam ST, LaPlante SR, Forgione P, Diz JSF, França TCC.   +10 more
europepmc   +1 more source

Molecular modeling-guided optimization of acetylcholinesterase reactivators: A proof for reactivation of covalently inhibited targets. [PDF]

Eur J Med Chem, 2021
Wei Z, Yang J, Liu Y, Nie H, Yao L, Yang J, Guo L, Zheng Z, Ouyang Q.   +8 more
europepmc   +1 more source

Treatment efficacy in a soman-poisoned guinea pig model: Added value of physostigmine?

, 2011
Current treatment of organophosphate poisoning is insufficient, and survivors may suffer from long-lasting adverse effects, such as cognitive deficits and sleep-wake disturbances.
Joosen, M.J.A., Smit, A.B., Helden, H.P.M. van   +2 more
core  

A tale of three mimickers: Amitraz, fipronil, and 2,4-dichlorophenoxyacetic acid poisoning confounding organophosphate toxicity. [PDF]

Turk J Emerg Med
Bhimani KS, Shinde V, Kanani P, Birru JD, Salam MAA.   +4 more
europepmc   +1 more source

Assessing oxime reactivation efficacy using principal component analysis: Insights from nerve agents inhibited human butyrylcholinesterase. [PDF]

ADMET DMPK
Šinko G, Čadež T, Kovarik Z, Hrvat NM.   +3 more
europepmc   +1 more source

Molecular Modeling Studies on the Multistep Reactivation Process of Organophosphate-Inhibited Acetylcholinesterase and Butyrylcholinesterase. [PDF]

Biomolecules, 2021
Jończyk J, Kukułowicz J, Łątka K, Malawska B, Jung YS, Musilek K, Bajda M.   +6 more
europepmc   +1 more source

Predictors of intermediate syndrome after organophosphorus poisoning and its management in Nepal. [PDF]

Acute Crit Care
Khanal K, Poudel S.
europepmc   +1 more source

Nanodiamond mediated delivery of pyridinium oxime antidotes to central nervous system for potential treatment of exposure to nerve agents. [PDF]

Chem Biol Interact
Bondar D, Smirnova O, Nagappa NM, Heinmaa I, Soukup O, Kobrlova T, Opravil J, Hrabinova M, Jun D, Starkov P, Spuul P, Kuča K, Mochalin VN, Karpichev Y.   +13 more
europepmc   +1 more source

Click-chemistry-derived oxime library reveals efficient reactivators of nerve agent-inhibited butyrylcholinesterase suitable for pseudo-catalytic bioscavenging. [PDF]

Arch Toxicol
Čadež T, Maček Hrvat N, Šinko G, Kalisiak J, Radić Z, Fokin VV, Sharpless KB, Taylor P, Kovarik Z.   +8 more
europepmc   +1 more source

Acute tubular necrosis with secondary acute respiratory distress syndrome after organophosphate poisoning: A rare clinical case. [PDF]

Respir Med Case Rep
Bereda G.
europepmc   +1 more source